<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05273

Description Uncharacterized protein
SequenceMPEQDIVFKIFNIVKCAALGTIKNSEFASTIKSAIENKTLTRKEMHQICGLIITAFFDEDNYGLKYLNPLESLINLCVISGDIVIGAILKTKFEKLDKKKIGNFFVLFKFVDFLVSKKKPTSSKGNDVMKVAEEILSIFNWYVELSTWDESETFTNYVAKRLFALLQNRYNCILLHATSKKSSECKKLLESRAVVLETKYPEISSYIRENVLIFKSTLERPYSSGLHHDFESISSMMTVYATLRTLESARDIAEAVYMASKNLQFTKIKMLYDMFKGVLYNFANNKTRREGRLFLGFAIIKFPKIIKSLICDLRVLDEIDIVATLAKIATESKLLCIVDFQCKYSFWELFISGLEREGVISESNMEQALYFRSLDYKENKETYENGLYLKPSINFPLNECINAWEYLIKLPLDNLSTVLTGLKHIIEKGGDVFGDSFGDSFGDSFTGILMTMWFKEELGNLSRLFSKINYLCQCKNDSLDDDSKAIRLELFDTTLILLFRIYFHFPDFTIEEFVGLPKKGEESENEESFLFYIWNTRIDKKINIPNDPEERTFEFDWDAPPIALIENPSDDVENELDQIINAISDGENSKNVKKSTEEDEKKVVQENDEKMDDTENLNLVGNDIKRDDINEGGEAKDDKENEGGEKMFEGSEVKIEGLKCASKVENDEEIDSQTRIIVDNLYKDKPFWNDEIDFAEAIKLIPKIAFTLYAIWCFRSMPSLVICLFQCLETGNNTHARNEVLDAIQIVLKKGEFDDKTVYDKWHFVYNIIGKKINDLVKIKAVQQPGTHFLISGFRKTLPVLEYKEIPHPHIIADAMIYTIKHNFVFPEALRIFDHYISVKGITSWCDSCFQELLRLETPDELDLASSLLLSIAFCRPSECFNEITKHIVDSILNADTWYMATHQPGRSALARLLVRSMCCMIWVSENRKHNEIYEKQLSFNEEDPNMNTLEIVFSRFYKETLSGHLKPTISFIIEFIYELAIAPQTPELSRLYSFVSRKFIFNLARLDPYSVTIDLYYRIFNFDDNGDNGLLQFATLHRFKGIL
Length1044
PositionTail
OrganismStrongyloides papillosus (Intestinal threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.11
Grand average of hydropathy-0.190
Instability index37.04
Isoelectric point5.15
Molecular weight120570.99
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05273
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     402.07|     134|     392|      50|     197|       1
---------------------------------------------------------------------------
   50-  197 (207.55/148.81)	GLIITAFFDEDnygLKYLNPLESLIN.LCVISGDIV...IGAIlktKFEKLDKKKIGNFFVLFKFVDFLVSK.....KKPTSSKGndvmkvaEEILSIFNWY......VELSTWDESETFT.NYVAKRLfALLQNRYNCI......LLHATS..KKSSECKKLLE..SRAVVLE
  447-  606 (194.52/111.60)	GILMTMWFKEE...LGNLSRLFSKINyLCQCKNDSLdddSKAI...RLELFDTTLILLFRIYFHFPDFTIEEfvglpKKGEESEN.......EESFLFYIWNtridkkINIPNDPEERTFEfDWDAPPI.ALIENPSDDVeneldqIINAISdgENSKNVKKSTEedEKKVVQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.47|      21|     143|     650|     670|       3
---------------------------------------------------------------------------
  621-  641 (33.92/23.94)	GNDIKRDDINEGGEAKDDKEN
  650-  670 (33.55/23.59)	GSEVKIEGLKCASKVENDEEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.78|      29|     426|     371|     408|       8
---------------------------------------------------------------------------
  371-  408 (48.45/47.31)	FRS....LDYKEnketyenglYLKPSI...........NFPLNECINAWEYLI
  794-  837 (42.33/24.34)	FRKtlpvLEYKE.........IPHPHIiadamiytikhNFVFPEALRIFDHYI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05273 with Med24 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISDGENSKNVKKSTEEDEKKVVQENDEKMDDTENLNLVGNDIKRDDINEGGEAKDDKENEGGEKMF
583
648










Molecular Recognition Features






MoRF SequenceStartStop




1) FEFDWDAPPIALIE
2) LFYIW
3) YYRIF
553
530
1017
566
534
1021