<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05272

Description Uncharacterized protein
SequenceMNDSKKVDECMPPPKTIPSSTTLTSDDSKFVKPIGIPNKSRKYVYVEPKKEWNVIEYSLEGTEALMPPKSFQESLAEKALRIDWKKIVGSNVTYDDPELVYDVESDKALDLVDKILTLKIHQKSYNPPTHHTNNSSKLVVKPNDLQINKSNGLHNEDKERIRFNKLVKEANEAGLELNDDNMDYEELSKHVDGASIDKIDGPISVTEVEQMVENNIVYENYRNRKFIEGETNLEKKKKSKDKESDDEDIGYMIGKAAIETFKEGRIVQELEDQGLPSAKKIIHNSQVASKIRYLVQKRLQRKTLEYHFIGMPLQNDEPKTIYQILKPSSNNAFGILPHDTSSEVFDPTKCDEFVKELTDRQIEAAKKAWDALELQTNEFDIFSQFKNDALEAKNRGEDIKTMSIHFGSTKIMIPVIVKDSFSSEPRKSDEMSSDSEDEDEDFQMEVDKESDGGDHVEPIPSVAFYINRSGKLLGCKIDGESYSLDKPEFLSNELTNRMLEAIENSEGNKKDEEMASEDGSLDSRGRNKEKDRDSSSRAQSPIVPEAGPWHKVAKNLHEALQHVNYLLDQLRVMDTSYMKPLTVAENTGDENTAINSKLYLWVAKRKALEESVGILETGTKHRKVDTESFEDKQAFFNELKSMREFWRLRKVGKFLTGDLGYRIFGSNFIPSESFDVTRKSSAILEEEKKHKSETGDTSPLSYLQVVVPYDLMRRTVMSVDIIIDHNAVTEGSLSKRKDNSDLEYMVVKPEDAMKVHWRKALLWAQESLICRDILKILFSDAAQATDIFSMQRENVLMVSLFSNVILKIQLDFYPFKDENLPQPGIPVLNTLLRHLFLSDLCIRPKLLQQFVTLPLIDSQDYIAGRTFSDASKSEMKEMINYTKHTTLLSRICKVASHYKLVQEVINELQNFSIQYSDPSLSWKFYRITSIESFINVVLSNRGFVDIIPKQSFTISITHDNILISIRAKEGKDLFECGHDLEIFVKSLKMVYCRYIINSIAIQSKHWVWYVLSSNLRFSESHYSDACDLTLYVSNVSGLYHIHFFINYVTLEKNITVERNIDLKWQENENSNSETDKDNEKYIYLDYNSLIGDSLLKKFDFLFAILR
Length1106
PositionHead
OrganismStrongyloides papillosus (Intestinal threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.09
Grand average of hydropathy-0.544
Instability index42.84
Isoelectric point5.39
Molecular weight127101.47
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05272
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.68|      27|     193|      55|      92|       1
---------------------------------------------------------------------------
   57-   85 (43.10/26.33)	YSLEGTEALMPPKSFQESLaeKALRIDWK
  626-  647 (32.95/13.58)	.....TESFEDKQAFFNEL..KSMREFWR
  661-  675 (18.63/ 6.62)	YRIFGSN.FIPSESFD.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     193.00|      60|      80|     426|     504|       3
---------------------------------------------------------------------------
  426-  486 (97.55/86.28)	RKSDEMSS.DSEDEDEDFQMEVDKESDGGDHVEPIPSVAFYiNRSGKLLGCKIDGESYSLDK
  509-  569 (95.45/50.48)	KKDEEMASeDGSLDSRGRNKEKDRDSSSRAQSPIVPEAGPW.HKVAKNLHEALQHVNYLLDQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.30|      14|      85|     267|     280|       5
---------------------------------------------------------------------------
  267-  280 (24.27/15.09)	VQELEDQGLPSAKK
  354-  367 (23.03/13.96)	VKELTDRQIEAAKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.44|      10|      34|     767|     776|       6
---------------------------------------------------------------------------
  767-  776 (18.33/12.81)	SLICRDILKI
  799-  808 (17.11/11.41)	SLFSNVILKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.60|      14|      35|     179|     193|       7
---------------------------------------------------------------------------
  179-  192 (24.08/17.70)	DDNMDYEELSKHVD
  200-  213 (21.52/ 8.49)	DGPISVTEVEQMVE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05272 with Med17 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ELTNRMLEAIENSEGNKKDEEMASEDGSLDSRGRNKEKDRDSSSRAQSPIVPEAGP
2) QKSYNPPTHHTNNSSKLVVKPNDLQINKSNGLH
3) SSEPRKSDEMSSDSEDEDEDFQMEVDKESDGGDHVEPIP
493
122
422
548
154
460










Molecular Recognition Features






MoRF SequenceStartStop




1) KSRKYVYV
2) SKFVKPIGI
39
28
46
36