<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05271

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMTTKNHKDIFDDYSNLFHKDSIANDVTLEDCHTNVLPLADISKLKWKCFRTNSRSTTKCKEAIKADLVLKAYSLCISENYICLWRRIPPDDFENDYPKGEFTLRSAKELWVFWFDKKEPRNLASYTCDLVVRDEYDGDHQNQIDVVRYDIRCLLFRAIHNLIERSLFTMGQKRFGKWFVATGTKEEVKQSMPQRNYSLAYGFSFFVHGEIMVCATINIQRQPLMKNRMLMSNFFAAYFAFILGPHGIRATLVADQIECVRREVVNISTKHKRDILVGKQYKEIETIAEEQYNDWRGFYPLPVYDSEDIKYRIPTVSEILPRMTLVEIDNLKMLWPTEYIGIIMDEYVCNGDRKCFYEKVVDEDQEVATIMANSKENSDLKPDNTNNRVMFDIERVDLECFCRHHNEDIDQNGRIFEDVIISSEYAVLPENDVEKPISNITSLPITENKEKDEKFENAMSFLMEIDNELKKEESKRMEIDDDDDIEKFLNFDNSIKGPNSKSPEKNSTESRNEKVDGNEKKDGDTKITKDKNDTIEEVKETVKIIVPKNVEPAVGNKWRYSNYCGKTDCVCPLCFKLGKMMLINPSKKFNKNDKNSTLKEELMNGDKEKENEPNVSTSYEKLVKQRLEAQTTIPKLPKRIPAPEKRVLEGKPIYGTGNFTLRDHTSNFQTMKNGDPKIFEEMKCLPEFNATKGTTSKELFPKFTPLIKTKFEYFRKKKYLLGRISHKKGKKKIYHTNNMMARLCLTPPTSRRNRLINKTRKRYLFPKEDTLMARDVTFYDKSIQHDTNEMLNSFISCIYDINNTKKYDYKIKIYKDFKISPSMDLKENYFDLLFQQFDNNDSDISGDTIYKRQLYKIKEKFLLNREESISLDSLDPFRWHSEGKETFESYYNLGDNESTLNHVPYYIIMNEYLYVIVDRKLERTKNEPNSMFSNERLFPISIDNDLTNNKKYFVGINNENEPQCDVVQKYFDNYLLNTKDECLEFNNKLNTFDATYEDKLPKTSFTKELVEGIYSGNIINELLESENEKEEDNNVNNHNKIVEIEDVEMASNFDVDEFLKEAGDSNSMEVDDSLFTTSNKKQNERDGVNLNEVENNITNSSSIDEDDDVIESILNDYRVKYDSNLDHYKMIYKNFICEKDNIIEDIGKENNSELSVILESINKEIGCSSSSIDYDVVTKNKKIKTNILGKNIFPGYLDDFCEWNRFFRDVDYDNIVPERLRPKKYDSFDLYRNTKHSCCDPFKQVLDEEKGVYGMPESYIRKNISKASVLTVIRKIVENVDIQRQAHERYINQLVKTSWKNIPLYSYFDSKNFPPKKILTDNFKNIVFIQEEKYIRNTNTSNIQEIISTVNGYKNDKTCRLSKSFEMSKVDQQSKRNLIRHRYERMLRAFEISNRFCPVRTADDSDITHMMFDYETQPSTMSMHNMSQHHPPNNDFFSHQQNFNIMDDFHGMGNNFNMNNSQHNQGFYNDPINYQNRHSNQFFSNQSGYPSLHPTITPFFDNFMNDNFDQMSNYNNLGSWNQMSHSNFPSRNSYQQNYLPNQNNVFGGNSNYGRNIPTALENDEEQTCIMKENETIEKTKNFKKSNKNNKYYHTTSDKFVGKNLLLKFNFRETIASETTNALNQNQYYTFTINDRLEGPFMNNSYDTINEDSTINEKKYFAKKFESQICINKNLKHIFTDEMGSFNALQHILNNYIFHNLYVEPTFYNTNYKKYTKKHYISKPTIESEQPTITSNDKLFEFNDLTYSDNGAKRRKIDLNLTNQENIHDMEVNNIPFFIEERSNVVRKQVNSYQGGSIFQIFPCTVGYSQVDYSNETSNDIEKWSEEMYKRINQEKSLLPTNISNPYNVNIRHLQYSIPHYSESYNDLITKYNNAKEIDKNYFVYSYDPETLENYRTDEFIKARYSSLNILFGSKNNINEIDEDGFVDDSLLGGMNNLDNNDQELIKSNKYIEHDYYTLMNEIAFRMVEKGDSEDFRNKVNHLCNMNRSPSLLSIVSFSGSDDDNEFIPPSKYNLNFSQNYFTYNSSNQHNPLDYNDIDEIYEVNDLDSSYEDDSNDSNSDGSNDSTDYDNSPINAFDEEMEIEIEKELKETEFNSSPNDSSEELVDSDSESESEVFNNTSNDDHFMVEDCEKCLKDNYQPLAVCRQLQNNWSGVNLIVQSIIPRYTNINDIYQLCLVADSQELFDNLRDSILKKIKKIKKNKLARESPDYYKIMRKIKEFGYTLPYESYILYREGPVVSYSHYLIHNDIDNCIHLPNCECCECLQLPPIPSYIDLDDPTSKNPYLFNYRNPKFINKGSTIYNISSTSKRYIPPMMSHHTFNNSLQLNDKLSCNIKYMNVIKCLNDKIDRTVRNKKYCNNGKIMGKEYPDAAAIIEVGRSTANIKVLNTSRPPDFLRLNEKGNPVTRDAYERLVTKKQYQKMKTKRLSLLKFKSPKIYFFKGYDSRSHEREGLYNNIISSSDRPFQYPDVIVEDSEKEDEYEEYYDLPSAHSYSEECPILENHADMSSNSLDSSSCNTSGINLLNPLTPGNPMTPSMNPLTPQMANPMTPGTSTLDGSQNINALTPNPGSISSSGPPSNYMNPGSNNYPNPGSNSYSNPGSNSYPNPGSNSYPNPGSNSYSNPASNTYPNPGSNSSVLQSIISQPNSQGNPQHFLPGNISSPSSFHGSGQMGQTMMQSPIMNSENQFMPNSGNYNFNRQMNQSCYNPMRDNYNSGMFQNMNNQNVFMGNDKHNVSYNNDGTNALYDHNQYNSNINQMASGDSMSNMRSEMNSNMSQMINSHYNNPMQQFNNSNNLPDRNSQHYPLETMNHQTSGNINQGYINSGSHHMVGGNQRVNYNNQMPDNQYYNKLPNMNYDNNSQNFVNNRNSYGDENNPNEVSYDSTFNNSVGNQHHQIPVNQGNEMFNAKNTSFNQSPGNNYPASNNYQMNYNQNNYMDSESNAQMFNNDDHEGSSMDGVYDDLLHPHSNRDNQQTFDNSPMPLLHNESNIAIEPLIIDSNTEYNCLYYKMEPETIPPASTLPLVETEKLAIDTNHILPMEPNKKVDVIRKDIISRREIKKDSIGISLLLHDSVFELHYDIIFDGCPICSCNSNIMSDDYGMYLRPPGILNKKGVTKSEWSGFYLAGDKNKCKCGFSALRHKLFSYNSGLFKEDAEEGSGLGAIYEQHPTKYHTFYNQLTEYDLSFINLIRIQSLNREMGAQIHSIESMLTKCNPPLTNAISNKYLSKCSNYMFSQVDINEKEHAIYNSLKASIEDDNESHLCIPNRNRKLIDYPSFLHPWSIQFPNNAKDATDADCFIILDNVSTFFKTLIHSTQCFGQEERKDVKTFTWSEFFKSATRSSKVQDECLQAPEPIPSVILASEKDLISSAPQIVCNWEKLGLSPIDQPKDVLYFVVTPDNDFVVEKTRLYFHELSKIYENYKLGRHIKLSKDIVEDGIFRVPIMIPDNCKIEGDSEQKYYDLFNEIISDKEYLDKMKSYAAFIEKQVFQFFEYNDILFDRRAYWECVKQELSGIPNISHDLSTTTSTISLQGIQDATSGNFPPGYYDHCSPPNMNRSGTEFDQQRPNSPIKDEDMTEMPHVIVIYIINPFNFGIKIKQPEQPKFALISLMRAFNVFLMKLNTTKRFRIQLEVINLQSIMDYAGYLCDKKRNERWYAPDPVYTRNKNFKFSAYEQLRNLSFAVYTHSRVYNTEDVRYVLAKSVTKFGYTSTVLDHVAEDIESGDKIFKLPCNLYRLSTQKRNPIQIIGKSLKRHIEDSVLFVSYCLVEDKWLVVTVSDHLGYLLDNCLINLQVTHKDNEIVKYKKGNRILDAISRLWVYIMGVLASETRNWRIVIGRFGRVGHTELKAWMHILSKSNIKRYNTKIKEACNLCAESLNSQSCPIIVSACFVSMEAEHNLRLFSNAVAKHKVMVPPISSNRSSKQKVIHSPDDVSVTHILVFPTTVDLSIDLTQGKDGQEKDDFENLMLDEGNDEIMELMKDGFDDVEDELKTAEPDNNHEENFFNIDAFEADASNQPMAIGYYISTAPTGKLPNWFWSQCPKAKDRCPVHLRNSLHIVTSNILQSDELMLNFKNTESTHPLDSTATDDVLRYVLKTYNALSWLNVDCVTSERRSCLPIHIQALARLCDAVETFMF
Length4128
PositionMiddle
OrganismStrongyloides papillosus (Intestinal threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.11
Grand average of hydropathy-0.750
Instability index47.79
Isoelectric point5.42
Molecular weight478634.01
Publications









Function






Annotated function

Component of the Mediator complex, a coactivator involved in
regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors. 


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05271
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.60|      15|      15|    2586|    2600|       1
---------------------------------------------------------------------------
 2586- 2600 (37.62/19.17)	YPNPGSNSY......SNPGSN
 2610- 2624 (36.11/18.01)	YPNPGSNSY......SNPASN
 2626- 2646 (24.88/ 9.45)	YPNPGSNSSvlqsiiSQPNSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.30|      17|      19|    2947|    2965|       3
---------------------------------------------------------------------------
 2706- 2722 (28.58/ 6.75)	MRDNYNSGMFQNMNNQN
 2952- 2968 (27.72/10.67)	MDGVYDDLLHPHSNRDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     128.10|      18|      19|    2910|    2928|       6
---------------------------------------------------------------------------
 1520- 1537 (34.95/14.93)	NQMSHS.NFPSRNSYQQNY
 2837- 2853 (27.88/ 8.98)	NQMPDNqYYNKLPN..MNY
 2910- 2927 (36.99/16.64)	NQSPGN.NYPASNNYQMNY
 2928- 2943 (28.28/ 9.32)	NQN..N.YMDSESNAQMFN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.63|      19|      19|     494|     512|       8
---------------------------------------------------------------------------
  494-  512 (31.56/19.30)	IKGPNSKSPEKNSTESRNE
  514-  532 (31.06/18.84)	VDGNEKKDGDTKITKDKND
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.79|      13|      19|    2325|    2337|       9
---------------------------------------------------------------------------
 2325- 2337 (25.94/14.86)	LNDKLSC...NIKYMN
 2342- 2357 (20.85/10.11)	LNDKIDRtvrNKKYCN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     149.29|      37|      37|    2032|    2068|      10
---------------------------------------------------------------------------
 1453- 1487 (29.83/ 9.15)	.........N.NFN....MN........NsqhnqgF...YNDPINyqnrH.SNQFFSNQSG
 2007- 2030 (35.77/12.72)	PPSKY....NlNFSQNYF....................TY....N....S.SNQHNP....
 2032- 2065 (54.56/24.02)	...DY....N.DIDEIYEVN........D......LDSSYEDDSN....D.SNSDGSNDST
 2066- 2112 (29.12/ 8.72)	DYD..nspiN.AFDEEMEIEiekelketE......FNSSPNDSSE....ElVDSDSESES.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     658.35|     216|     349|    2995|    3241|      11
---------------------------------------------------------------------------
 2995- 3241 (326.91/258.23)	SNTEYNCLyykMEPETIPP...ASTLPLVETEKLAIDTNHILPMEP.NKKVDVIRKDIISRREIKKDSigISLLLHD..SVFElHYDIifdGCPIcSCNSNIMSDdyGMYLRP...PGILNKKGVTKSEWSGFY..LAGDK...NKCKcGFSALRHK....LFSYNSGLFKEDA......EEGSGLGAIyeqhptkyhtfynqltEYDLS.FINLIRIQSLNREMGAQIHsiESMLTKCNPPLTNAISNKYLSKCSNYMFSQVDINEKEHAI
 3337- 3577 (331.44/192.47)	SKVQDECL...QAPEPIPSvilASEKDLISSAPQIVCNWEKLGLSPiDQPKDVLYFVVTPDNDFVVEK..TRLYFHElsKIYE.NYKL...GRHI.KLSKDIVED..GIFRVPimiPDNCKIEGDSEQKYYDLFneIISDKeylDKMK.SYAAFIEKqvfqFFEYNDILFDRRAywecvkQELSGIPNI................SHDLStTTSTISLQGIQDATSGNFP..PGYYDHCSPPNMNRSGTEFDQQRPNSPIKDEDMTEMPHVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     105.10|      22|      23|     889|     910|      12
---------------------------------------------------------------------------
  886-  906 (32.69/14.11)	.FES.Y.YNLG.DN..ESTLNHVPYYI
  907-  930 (26.69/10.07)	IMNE.YlYVIV.DRklERTKNE.PNSM
  931-  953 (24.91/ 8.87)	FSNErL.FPISiDN..DLT.NNKKYFV
  955-  969 (20.81/ 6.11)	INNE.........N..EPQCDVVQKY.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.25|      19|      61|    1429|    1451|      13
---------------------------------------------------------------------------
 1429- 1451 (31.89/26.46)	HPPNNDFFshqQNFnIMDDFHGM
 1492- 1510 (40.36/20.06)	HPTITPFF...DNF.MNDNFDQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.25|      42|      61|     581|     640|      14
---------------------------------------------------------------------------
  594-  635 (67.18/46.44)	NSTLKEELMNGDKEKENEPNVSTSYEKLVKQRLEAQTTIPKL
  657-  698 (69.07/36.18)	NFTLRDHTSNFQTMKNGDPKIFEEMKCLPEFNATKGTTSKEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.49|      21|     348|    2115|    2138|      15
---------------------------------------------------------------------------
 2115- 2136 (37.05/27.26)	FNNTS................NDDH..FMVEDCEKcLKDN
 2147- 2185 (25.45/ 6.82)	QNNWSgvnlivqsiiprytniNDIYqlCLVADSQE.LFDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     172.13|      67|     349|     778|     877|      16
---------------------------------------------------------------------------
  753-  829 (98.98/63.12)	RLINKTRKRYLFPKEDTL.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................mardvtfYdKSIQHDtNEMLNSFISCIYDInNTKKYDYKIKIYKD......FKISPSMDLKENYF
  851-  868 ( 4.98/19.20)	RQLYKIKEKFLLNREESI........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 1827- 1881 (68.17/22.92)	..................sldsldpfrwhsegketfesyynlgdnestlnhvpyyiimneylyvivdrklertknepnsmfsnerlfpisidndltnnkkyfvginnenepqcdvvqkyfdnyllntkdeclefnnklntfdatyedklpktsftkelvegiysgniinellesenekeednnvnnhnkiveiedvemasnfdvdeflkeagdsnsmevddslfttsnkkqnerdgvnlnevennitnsssidedddviesilndyrvkydsnldhykmiyknficekdniiedigkennselsvilesinkeigcssssidydvvtknkkiktnilgknifpgylddfcewnrffrdvdydnivperlrpkkydsfdlyrntkhsccdpfkqvldeekgvygmpesyirkniskasvltvirkivenvdiqrqaheryinqlvktswkniplysyfdsknfppkkiltdnfknivfiqeekyirntntsniqeiistvngykndktcrlsksfemskvdqqskrnlirhryermlrafeisnrfcpvrtaddsdithmmfdyetqpstmsmhnmsqhhppnndffshqqnfnimddfhgmgnnfnmnnsqhnqgfyndpinyqnrhsnqffsnqsgypslhptitpffdnfmndnfdqmsnynnlgswnqmshsnfpsrnsyqqnylpnqnnvfggnsnygrniptalendeeqtcimkenetiektknfkksnknnkyyhttsdkfvgknlllkfnfretiasettnalnqnqyytftindrlegpfmnnsydtinedstinekkyfakkfesqicinknlkhiftdemgsfnalqhilnnyifhnlyveptfyntnykkytkkhyiskptieseqptitsndklfefndltysdngakrrkidlnltnqenihdmevnnipffieersnvvrkqvnsyqggsifqifpctvgysqvdysnetsndiekwseemY.KRINQE.KSLLPTNISNPYNV.NIRHLQYSIPHYSEsyndliTKYNNAKEIDKNYF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     197.31|      64|      67|    1040|    1105|      17
---------------------------------------------------------------------------
 1040- 1105 (99.61/79.64)	IVE..IEDVEMASNFDVDEFlkEAGDSNSMEVDDSLFTTSNKKQNERDGVNLNEVENNIT.NSSSIDED
 1108- 1174 (97.70/71.36)	VIEsiLNDYRVKYDSNLDHY..KMIYKNFICEKDNIIEDIGKENNSELSVILESINKEIGcSSSSIDYD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.62|      42|     348|     183|     232|      20
---------------------------------------------------------------------------
  183-  232 (71.70/61.43)	TKEEVKQSMP...QRNYSLAYG....FSFFVHGEIMVCatiniqrqPL.MK.NRMLMSN
  533-  583 (58.92/35.84)	TIEEVKETVKiivPKNVEPAVGnkwrYSNYCGKTDCVC........PLcFKlGKMMLIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.61|      16|      16|    2480|    2495|      23
---------------------------------------------------------------------------
 2480- 2495 (29.38/13.53)	EEYYDLPSAHSYSEEC
 2499- 2514 (23.23/ 9.06)	ENHADMSSNSLDSSSC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.63|      14|      19|    1909|    1922|      25
---------------------------------------------------------------------------
 1909- 1922 (24.42/13.64)	LFGSKNNINEIDED
 1929- 1942 (25.21/14.40)	LLGGMNNLDNNDQE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.48|      13|      37|    2768|    2780|      26
---------------------------------------------------------------------------
 2768- 2780 (25.90/17.74)	MNSNMSQMINSHY
 2806- 2818 (24.58/16.30)	MNHQTSGNINQGY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.26|      22|     348|      28|      49|      28
---------------------------------------------------------------------------
   28-   49 (41.24/32.42)	LEDCHTNVLPLADISKLKWKCF
  379-  400 (40.03/31.16)	LKPDNTNNRVMFDIERVDLECF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.27|      14|      21|    3260|    3273|      30
---------------------------------------------------------------------------
 3260- 3273 (25.68/14.35)	PNRNRKLIDYPSFL
 3281- 3294 (25.59/14.27)	PNNAKDATDADCFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.96|      25|      37|    1568|    1593|      31
---------------------------------------------------------------------------
 1568- 1593 (39.93/28.26)	IMKEN..ETIeKTKNFKKSNKNNKYYHT
 1604- 1630 (38.03/21.77)	LLKFNfrETI.ASETTNALNQNQYYTFT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     196.24|      81|     503|    1727|    1818|      33
---------------------------------------------------------------------------
 1727- 1767 (50.67/30.47)	......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EQPTITSNDKLFEFNDLTYSDNGAKRRKIDLNLTNQENIHD
 1774- 1818 (41.94/29.89)	PFFIEERSNvvrKQVNsyQGGSIFQIFPCTVGYSQVDYSNETSND..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 2282- 2321 (54.61/25.62)	PYLFNYRNP...KFIN..KGSTIYNISSTSKRYIPPMMSHHTFNN..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................
 3595- 3635 (49.02/17.97)	.............................................slqlndklscnikymnvikclndkidrtvrnkkycnngkimgkeypdaaaiievgrstanikvlntsrppdflrlnekgnpvtrdayerlvtkkqyqkmktkrlsllkfkspkiyffkgydsrshereglynniisssdrpfqypdvivedsekedeyeeyydlpsahsyseecpilenhadmssnsldssscntsginllnpltpgnpmtpsmnpltpqmanpmtpgtstldgsqninaltpnpgsisssgppsnymnpgsnnypnpgsnsysnpgsnsypnpgsnsypnpgsnsysnpasntypnpgsnssvlqsiisqpnsqgnpqhflpgnisspssfhgsgqmgqtmmqspimnsenqfmpnsgnynfnrqmnqscynpmrdnynsgmfqnmnnqnvfmgndkhnvsynndgtnalydhnqynsninqmasgdsmsnmrsemnsnmsqminshynnpmqqfnnsnnlpdrnsqhypletmnhqtsgninqgyinsgshhmvggnqrvnynnqmpdnqyynklpnmnydnnsqnfvnnrnsygdennpnevsydstfnnsvgnqhhqipvnqgnemfnakntsfnqspgnnypasnnyqmnynqnnymdsesnaqmfnnddhegssmdgvyddllhphsnrdnqqtfdnspmpllhnesniaiepliidsnteynclyykmepetippastlplveteklaidtnhilpmepnkkvdvirkdiisrreikkdsigislllhdsvfelhydiifdgcpicscnsnimsddygmylrppgilnkkgvtksewsgfylagdknkckcgfsalrhklfsynsglfkedaeegsglgaiyeqhptkyhtfynqlteydlsfinliriqslnremgaqihsiesmltkcnppltnaisnkylskcsnymfsqvdinekehaiynslkasieddneshlcipnrnrklidypsflhpwsiqfpnnakdatdadcfiildnvstffktlihstqcfgqeerkdvktftwseffksatrsskvqdeclqapepipsvilasekdlissapqivcnweklglspidqpkdvlyfvvtpdndfvvektrlyfhelskiyenyklgrhiklskdivedgifrvpimipdnckiegdseqkyydlfneiisdkeyldkmksyaafiekqvfqffeyndilfdrraywecvkqelsgipnishdlstttstislqgiqdatsgnfppgyydhcsppnmnrsgtefdqqrpnspikdedmtemphviviyiinpfnfgikikqpEQPKFALISLMRAFNVFLMKLNTTKRFRIQLEVINLQSIMD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.22|      22|      39|    1178|    1199|      38
---------------------------------------------------------------------------
 1178- 1199 (38.33/20.01)	KNKKIK....TNILGKNIFPGYLDDF
 1202- 1227 (35.90/18.25)	WNRFFRdvdyDNIVPERLRPKKYDSF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.32|      10|      25|    3300|    3309|      39
---------------------------------------------------------------------------
 3300- 3309 (18.47/ 9.96)	STFFKTLIHS
 3327- 3336 (17.85/ 9.35)	SEFFKSATRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.20|      15|      21|    1656|    1675|      40
---------------------------------------------------------------------------
 1666- 1681 (21.08/11.40)	QICINKNLKH..iFTDEM
 1688- 1705 (20.12/12.35)	QHILNNYIFHnlyVEPTF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.53|      10|      16|    3859|    3868|      53
---------------------------------------------------------------------------
 3859- 3868 (18.56/10.84)	IKEACNLCAE
 3878- 3887 (17.98/10.25)	IVSACFVSME
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.10|      17|      31|    2202|    2218|      55
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 2201- 2217 (30.88/22.52)	K...........LARESP....DYYKIMRKIK
 2218- 2249 (18.21/ 8.90)	EfgytlpyesyiLYREGPvvsySHYLIHNDID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.72|      19|      25|    3636|    3660|      56
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 3636- 3660 (20.63/27.12)	YAGYlcDKKRNERwYApdpVYTRNK
 3664- 3682 (34.09/15.79)	FSAY..EQLRNLS.FA...VYTHSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      25.53|       8|      28|    2442|    2452|      58
---------------------------------------------------------------------------
 2442- 2452 (10.22/13.03)	DSrshEREGLY
 2472- 2479 (15.31/ 6.79)	DS...EKEDEY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05271 with Med13 domain of Kingdom Metazoa
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