<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05267

Description Uncharacterized protein
SequenceMIDTKFRDELASKRERVELLYSFRGSKIGRGTYGHVYKATPRFETPENKGKTYALKLIEGNGISMSSCREIALLRELSHPNLIKLNRVFLSPERKVWLLFDYAEHDLWHIIKFHRNAKQKKQAVMVPKSMVKSLLFQILDGIHYLHTNWILHRDLKPANILVMGDDPYERGRVKVADMGFARTFHTPVRPLADLDPVVVTFWYRAPELLLGAKHYTKAIDIWAIGCIFAELLTSEPVFFCREEDIKASSPYHKDQLSRIFQVMGYPQDADWPDLKKMPEYQRLSKDFKRQTFSECALYKYLEKHKVKTNDKGFSLLQKLLTFDPLKRISAIDAINDAFFKESPKPTLDVFRGGPIPYPRREFMQDENEEKIIGKHIPQQNIQIQQHMINNKLVQQGNNQIRQIPEPDIKSNQFSNITMANQPEFNHLNNHSGNLNQPPPQQVNVFNDGNQQNVVQMQQNQYNQQAIFTGHDQNRMIMQQQQQQPVVQNAIRGPNGQFISQQQSRIISQDQNRMMMPQNQHQFNQQQQQMFVSHDQNRMMMQQQNRMIQSQGQNNMMPMQQPYIQPQQQHQIPPQQQQQQQQQQQQMMQQQNFMWNQQQRYQ
Length601
PositionKinase
OrganismStrongyloides papillosus (Intestinal threadworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Strongyloides.
Aromaticity0.09
Grand average of hydropathy-0.812
Instability index49.82
Isoelectric point9.44
Molecular weight70883.12
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05267
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     142.76|      18|      18|     456|     473|       1
---------------------------------------------------------------------------
  456-  473 (35.88/12.54)	MQQN..QYNQQ..AIFTGHDQN
  515-  536 (25.41/ 6.83)	MPQNqhQFNQQqqQMFVSHDQN
  540-  553 (26.63/ 7.49)	MQQ......QN..RMIQSQGQN
  558-  575 (24.38/ 6.26)	MQQPyiQPQQQ....HQIPPQQ
  576-  591 (30.46/ 9.58)	QQQQ..QQQQQ..QMM..QQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     123.85|      33|      39|      98|     132|       2
---------------------------------------------------------------------------
   73-   97 (41.67/29.28)	LLRELSH..PNL......IKLNR.......VFLSPERKVW
   98-  132 (54.31/48.55)	LLFDYAE..HDL...WhiIKFHRNAKQKKQAVMVPKSMVK
  134-  163 (27.88/16.95)	LLFQILDgiHYLhtnW...ILHRDLKPANILVM.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.14|      23|      39|     191|     217|       3
---------------------------------------------------------------------------
  191-  217 (33.50/40.97)	LADL...DPVvvtFWYRAPELLlGAKHYTK
  228-  253 (37.65/29.47)	FAELltsEPV...FFCREEDIK.ASSPYHK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      89.27|      21|      24|     364|     385|       4
---------------------------------------------------------------------------
  364-  385 (31.45/14.76)	QDENEEKiIGKHIPQQNIQIQQ
  394-  412 (28.93/10.04)	QQGNNQI...RQIPEPDIKSNQ
  487-  507 (28.89/10.01)	QNAIRGP.NGQFISQQQSRIIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05267 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IQQHMINNKLVQQGNNQIRQIPEPDIKSNQFSNITMANQPEFNHLNNHSGNLNQPPPQQVNVFNDGNQQNVVQMQQNQYNQQAIFTGHDQNRMIMQQQQQQPVVQNAIRGPNGQFISQQQSRIISQDQNRMMMPQNQHQFNQQQQQMFVSHDQNRMMMQQQNRMIQSQGQNNMMPMQQPYIQPQQQHQIPPQQQQQQQQQQQQMMQQQNFMW
383
594










Molecular Recognition Features






MoRF SequenceStartStop




NANANA