<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05250

Description Uncharacterized protein
SequenceMVEGENEPAMTVSATAVGKDAERLQQMILNFVGFVLFDAVQMREIFWDIDADQGIGSVCYEALDLLKSMTDMKCSNCRKRIDEYVESGICFYLKFLHLIGFSECCEFLVTCTDFTLRHRIDAKKFEFMQEKLHLIDYKGLRSILKLLVVDRMQEMPTQISHYHRQMLLPLENILLTLIERQLNLLPCLFTITELQRMSTNSRAFLLPRVAKKFNELFISFRPLAEMVVVIGRPWLFPISTHISFVLVANSWKLEPGTTKIHQRAHLPYRSELFAPQSALLYTLLRQPRGKEALTWLMRPYSNAPRVQCDELLQMIILEAMSEMEKTDIRVDNPVNQYQWMNITHTVTYSLFHGFASFSRLLQILYESLTETVYRKGRAELMWIILQYVAVCLPQITTEDMQKIADIYNLLYKGEETFCGVDTDPLFFVRIFVPAAIWINFYTKDPGTTPKPSESLQSQIKFLKQMADADQNPALKNVADHNAVLAAVANAYSNDMETFTKLVLDNVESFLDCKADEREQLPYMVMCHGRRVPLSLILIDSLTIQSRYRLLQMLVTKLHTIIQMTPPVRYPSPAVVGFIIRTWLSFNVFFXXXXXXXXXXXXXXXTTDYEYAVKQLVGLVTCTLEQLNQINPGDLSGKADRAKDLLYILCEIFSYCLVNIPYPASNKSTILHTSYMALSSASVHVNGALYSAFEQVLLRFWMWNSPQEMYILNNQLIGKQGKLAYLVMSPDTFNEFQSGTYNDRVVNISPELIRCFLLSFFRCLKITGMPIHVIFRINKNFVWPLSTSQSFVAQIPNCTTDDGTDYAHMNEFCHCVMRDTRQIRDYLYSATGEEQIIKYFSENRNMDNLFCVIYLLLCEIKKCHPVFYSILKKMSARQIIIMTNKLAEYVIHTARFSLPDDASFRTMTNALNEMIFNYHLVSFERFLLSFVLHPTDDDSTQAALVIIHDLVGSYADLSTRLNFLFNVVPSNKLVSNNTVFFGKLVEYYAQYPELSYKEMEVKLRYGARLDVSMRRNDTCIDQSEHMPIYYGNLAERILPIVDVLLFRALEIGVADEIFDNLLSQFKCCYKYHPQPANFLYSVLYCLDKKLSHTLRAQKFVSEICSQVAERDGSNQLVVSIDQRLEPPELCMSLVDRILQGATYAHKPPSFACKDWRFAELPPAGQALTGACIELLASQHLPNVTVRALIEIAFVRPLRQPYAAINAITLILTSLPPSFQQKFFDHIVNVVACKELRDGDPSVCFESLESECFLLTESYLMTNLALCHAYMQHCTNYSLSVLPAFVQERLLPILETESQLIFVLRLVLPILQRFYDTKEKSKQLQDVSYYLLFWIMMNLLIYFLRGVNEIVGSFKYEDTVCDFLYHMKYMYVGDFIKNEAEQAIQKLSPSMREKLILSGGKKPNGHPFSQSMRIVRECSWYWGNISWQKAERLLLKQEPGTFLIRDSASDRYIFTLSYRTADSVLHTRLPRHGEYFCLGGLLLCPNTLVKANSLVTFVEESIRNCEKRGVCLLMHKKDVRTGTDMLALVKPLRRHEVLPSLNVPSVICSSQISIWTLRKFSTIYALSSGCLPSAIAVVRISGPDSKHCLQFLTGKKHFEPRKMFYTKLYTAEHEVIDRSMSVFLSGPNTYTGEDSVELFVHGSRALVHCLFQTLNQLKNVRPAKAGEFTKRAFLNSKMTFQDVTRLPYLISAQTGRQHSLATKGAEISSSVVSVRQKLVNTMAILEARIDFAEDIHFDFDDFIANVTTLTEELKCIKQRVMRGKLITSGLKAVIIGRTNAGKSSLFNRIAAKEIAIVSPQEGTTRDSLETAVEIAACPVIFTDTAGIRETSDLVERQGVLRTKNKVSEADLVIVVVDVTEVINPETYVRHLLLESEVKKDVPVVVVFNKVELLKEKPRYNLPWKNVFVSCLSGSGMDTLINLIGNVVDSLCGSIDTDAILSQERQRFLLETAISSLDIVSKANRTSDLAILSQTLRKAVDAVGEISGAIVNEEILDNIFANFCIGK
Length2004
PositionTail
OrganismSyphacia muris
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Oxyuridomorpha> Oxyuroidea> Oxyuridae> Syphacia.
Aromaticity0.10
Grand average of hydropathy0.038
Instability index43.18
Isoelectric point6.85
Molecular weight227046.22
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GTP binding	GO:0005525	IEA:UniProtKB-KW
GTPase activity	GO:0003924	IEA:InterPro

GO - Biological Process
tRNA modification	GO:0006400	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05250
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     346.62|     123|     141|    1694|    1832|       1
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 1694- 1831 (163.52/168.65)	RQHSLATKG....AEISSSVVSVRQkLVNTMAILEaRIDFAEDIHFDFDDFIA.NVTTLTEE...LKCIKQRVMRGKLITSGLKAVI..IGRTnagKSSLFNRIAAKeiAIVSpQEgTTRDSLETAveIAACPVIftdtAGIRETSDL
 1834- 1966 (183.11/128.67)	RQGVLRTKNkvseADLVIVVVDVTE.VINPETYVR.HLLLESEVKKDVPVVVVfNKVELLKEkprYNLPWKNVFVSCLSGSGMDTLInlIGNV...VDSLCGSIDTD..AILS.QE.RQRFLLETA..ISSLDIV....SKANRTSDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.49|      27|     316|     755|     788|       2
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  755-  788 (33.07/42.52)	FLLSFFRCL..KITgmpiHVIfRINKnFVWPLsTSQ
 1077- 1105 (45.42/26.63)	FLYSVLYCLdkKLS....HTL.RAQK.FVSEI.CSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.04|      31|     140|    1464|    1499|       3
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 1464- 1499 (45.54/36.83)	HTRLPRHGEYFcLGGlllcPNTLVKANSLVTFVEES
 1611- 1641 (55.49/28.92)	HEVIDRSMSVF.LSG....PNTYTGEDSVELFVHGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     474.53|     152|     187|     203|     368|       4
---------------------------------------------------------------------------
  143-  202 (26.76/ 8.03)	.....................................................................................................................ILKLLVVDRMQEM.P.TQI.....................SHYHrqmllpLENILLTLierQLNLL....PCLFTITELQRMSTNSR
  203-  368 (246.20/234.90)	AFLLPRVA....KKFNELFISFRPLAEMVVVIGRPWLFPISTHISFVLVANSWKLEPGTTkihqrahlPYRSELFAPQSALLYTLL...RQPRGKEAL..TWLMRPYSNAPRvqcdeLLQMIILEAMSEMEK.TDIRVDN...............PvNQYQ......WMNITHTV...TYSLF....HGFASFSRLLQILYESL
  389-  557 (201.57/159.96)	AVCLPQITtedmQKIADIYNLLYKGEETFCGVDTDPLFFVRIFVPAAIWINFYTKDPGTT........PKPSESLQSQIKFLKQMAdadQNPALKNVAdhNAVLAAVANAYS...............NDMETfTKLVLDNvesfldckadereqlP...YM......VMCHGRRV...PLSLIlidsLTIQSRYRLLQMLVTKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.52|      33|     315|     896|     931|       5
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  898-  930 (57.11/44.08)	PDDASFRTMTNALNEMIFNY.HLVSFERFLLSFV
  934-  967 (49.41/25.81)	TDDDSTQAALVIIHDLVGSYaDLSTRLNFLFNVV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.80|      50|     147|    1358|    1417|       9
---------------------------------------------------------------------------
 1358- 1417 (74.67/72.01)	VCdFLYHMKYMYVG.DFIkneaeqAIQKlsPsMREKLILSGGKKPNGHPFSQ.SMRIVRECS
 1508- 1559 (81.12/50.33)	VC.LLMHKKDVRTGtDML......ALVK..P.LRRHEVLPSLNVPSVICSSQiSIWTLRKFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.01|      17|     338|     802|     820|      10
---------------------------------------------------------------------------
  802-  820 (31.36/24.42)	GTDYAHMNEFCHCvmRDTR
 1139- 1155 (35.64/21.00)	GATYAHKPPSFAC..KDWR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.90|      36|    1006|      18|      60|      11
---------------------------------------------------------------------------
   18-   60 (55.52/56.05)	GKDAERlqqmILNFVGFVLFDAVQM...REIFwdiDADQGIGSVCY
 1030- 1068 (60.38/39.65)	GNLAER....ILPIVDVLLFRALEIgvaDEIF...DNLLSQFKCCY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.89|      21|      60|    1585|    1605|      12
---------------------------------------------------------------------------
 1585- 1605 (42.07/28.74)	HCL.QFLTGKKHFEPRKM.FYTK
 1646- 1668 (29.83/18.12)	HCLfQTLNQLKNVRPAKAgEFTK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05250 with Med23 domain of Kingdom Metazoa
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