<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05236

Description Uncharacterized protein
SequenceMAAIIPMQQKNEEHHKEDEDYRKYKPCMSDCERLFRIIYRYLTSTAVDYLLENDVDGDIRNQKITILECYRLLEHMADNDRRGLALKFCIENLQLCDDISSKRHVYEEMITFIINKLYKNELIHHYHCFELHILNTDYKLKNPIDKRKFEFMEQNMHLLDYKEKRNIMKALLVERFEKIPINITENQREKAYPIEQFVLKIMDRENNYMPSLFTITEVFRLTSSATAYIFPRISRKLTNIILTFRPLAEMIIPIGRVWLFPIVSHIGYNSSNNTWKLADSEPYRFYLKPHLPYSTEFKANQSFFLYMMLKQPRGNAVIKTIFVKSVPLITNSKLNVTELLQLFILEAMYECESTTLPTHHPAVQYTWLNLQHLCEFCIFHNNASFLDLLRLLKKSLKEFNYKKARDELMWLFLQHVTINIRKFQRECMIEIAEIYKILYTGNEEWIGSSLDINKMVKFFAPAAIWMCYEKERKEDFPKPSPIIKNHMELFKKEAMKGGELHDGMLIVIGNAISTDKIDFQEKFYKVLLKQLQSNDEEEKWTLPYGRKVDKRLKAIELNSLDCFTFHAKDMIAKHLMCLFGPNNPNIYSVSPAIIESLVRIIMSVEVFDTTKIQFLNLLGYYISNQNLDLAYVIAEAICFKIIDLHMHSSQRHIVIRAAIDGLKRLSLMDQSNFLFSTLEQIVIRSFMWYNPHDMCHLFVKCFTDKNSDLASHVSLPVTEYTGDLNNISMLISPEMVKIMYFTYLKNLKLTGIEAPPETVRIINEXKYINQNTGEFVSRQEINENFLISLVETVHNDPMVKSLKMPEEYLGRTRNNYIIYCVIFKVLEDNLLPELNPCFYKILALLNPKELTLSCNTFIEYLILRFRNVEKEEEKLIKIVNDMIFKHHITTFDRFLLALIMHPDDDASMTISFNILYALLTNCNDLQHRLATCVTFIPRREFSCRADSEKMFKKMALYHKTYPEHAHKELIHKLDRKDDFSMPDVYLPIYYRNLAEIIIPIVDMMLTKAILLNYEFEKFVVILKVFYMVYAYHPAPLSFLYGVLFLLDCDHEKEPLHFQVLVKKIISVSQTIISFTANFYQKESFLYPSADETCTEIVGKLMEGCNIKLIPPKHVARDWRFHEFAPAGQALYTGAIELMFCNLPSKDIAENLLSIAVPRSGENYHEKINAACSLLTALPMSYQEHIFPFMFNAITSDEMVNCKDPKMIFSSIEDVLYHCHDFDSIPYLAVIQTYWQLAPMGMFVKGVEFFEEVMIDIIDNEAQLLYAARIILPFILKMSEAREKFKKDETTKCVSALYDMIGKICSNYEVPLAYESLICDIMYFIKYIFVGDVVRDKAEDVIKKMPPHLQEVMKYYNPASNTDEINRATHTTSISLLCNPLITFQNIPAPLDYEELCSNQNPELNNQYEVMNAFPVTGSTLQRMQQSYDYTNIKQENVENRAPQPNMQDFKPSQLQQQLQNPAMDIHMQQQGMHNFNPRTQNEMREEYANMMRNEATQIHMENQQKMSQMGMFPGQGANQQMNMTGVHQMHPGDPRFQGDMRMQQKFSQQHPMNMHPAMLNKQQPMSHQGGAGQAQPMNTFGNPPQYSNMMHQQGMPPYNQMMAGKQPQMMHPGRIPPNFNMASSINPYTNPQQFSNMPRHPNMPMQGNVPNPHGMAQPGMSPIYPQQSHMYQNMPNQSGFPMHMQGHGFNQQRM
Length1694
PositionTail
OrganismParastrongyloides trichosuri (Possum-specific nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Parastrongyloides.
Aromaticity0.11
Grand average of hydropathy-0.288
Instability index49.30
Isoelectric point6.40
Molecular weight198095.83
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05236
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     270.89|      40|      43|    1497|    1536|       1
---------------------------------------------------------------------------
 1432- 1464 (28.86/ 9.53)	IK....Q...................eNV.ENRA.PQPN...MQDFkP....SQ....L..QQ........QLQnpAMD
 1465- 1490 (23.90/ 6.62)	IHmqqqGM.HNF..NPR....T..QN.EMrEE.............Y............A..N..........M......
 1491- 1525 (62.60/29.41)	.......M.R....NEA....T..QI.HM.ENQQ.KMSQ...MGMF.P....GQ...GA..NQ........QMN..MTG
 1526- 1566 (54.69/24.74)	VH....QM.HPG..DPR....F..QG.DM.RMQQ.KFSQqhpMNMH.P..........AmlNK........QQP..MS.
 1567- 1609 (33.50/12.27)	.H....QG.GAG..QAQpmntF..GN.PP.QYSN.MMHQ...QGMP.P...yNQmmaGK..QP........QM......
 1610- 1647 (29.26/ 9.77)	.......M.HPGriPPN....F............nMASS...IN...P....YT...NP..QQfsnmprhpNMP..MQG
 1652- 1692 (38.09/14.97)	PH....GMaQPG.mSPI....YpqQS.HM...YQ.NMPN...QSGF.PmhmqGH...GF..NQ........Q.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.95|      36|      43|     805|     840|       2
---------------------------------------------------------------------------
  805-  840 (63.45/35.60)	PEEYLGRTRNNYIIYCVI.FKVL...EDNLLPELNPCFYK
  847-  885 (50.12/26.56)	PKE.LTLSCNTFIEYLILrFRNVekeEEKLIKIVNDMIFK
  982- 1007 (46.37/24.02)	PDVYLPIY...........YRNL...AEIIIPIVDMMLTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     111.28|      34|      43|    1342|    1375|       4
---------------------------------------------------------------------------
 1342- 1362 (29.95/12.76)	.....................KKMPPHL..QEVMKYYNPASNTD
 1363- 1406 (45.69/23.28)	EINRATHTTSISLlcnplitfQNIPAPLdyEELCSNQNPELNNQ
 1408- 1431 (35.64/16.56)	EVMNAFPVTGSTL........QRM......QQSYDYTN......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.58|      18|      38|      18|      35|       5
---------------------------------------------------------------------------
   18-   35 (36.24/21.74)	DEDYRKYKPCMSDCERLF
   56-   73 (32.34/18.62)	DGDIRNQKITILECYRLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.29|      17|      38|     292|     308|       6
---------------------------------------------------------------------------
  292-  308 (33.37/18.68)	PYSTEFKAN.....QSFFLYMM
  327-  348 (23.92/11.42)	PLITNSKLNvtellQLFILEAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.81|      15|      38|    1010|    1024|       7
---------------------------------------------------------------------------
 1010- 1024 (25.73/19.16)	LLNYEFEK....F.VVILKV
 1045- 1064 (17.08/ 9.66)	LLDCDHEKeplhFqVLVKKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.79|      60|     108|     458|     519|       8
---------------------------------------------------------------------------
  458-  519 (101.22/66.54)	FFAPAAI...WMCYEKERKEDFPKPSP.IIKNHMELFKK.EAMKGGELHdgMLIVIGNAISTDKIDF
  565-  629 (88.57/51.99)	FHAKDMIakhLMCLFGPNNPNIYSVSPaIIESLVRIIMSvEVFDTTKIQ..FLNLLGYYISNQNLDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.42|      10|      22|     137|     146|       9
---------------------------------------------------------------------------
  137-  146 (19.26/12.41)	DYKLKNPIDK
  160-  169 (19.16/12.30)	DYKEKRNIMK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.75|      17|      44|     212|     228|      12
---------------------------------------------------------------------------
  212-  228 (25.86/17.61)	LFTITEVFR.....LTSSATAY
  237-  258 (21.05/12.77)	LTNIILTFRplaemIIPIGRVW
  259-  275 (29.84/21.62)	LFPIVSHIG.....YNSSNNTW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.74|      18|     271|     439|     457|      14
---------------------------------------------------------------------------
  439-  457 (27.72/22.62)	YTGNEEWIgSSLDINKMVK
  720-  737 (31.02/20.00)	YTGDLNNI.SMLISPEMVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.11|      26|      45|    1244|    1269|      16
---------------------------------------------------------------------------
 1244- 1259 (18.66/ 8.96)	...............................KGVEFFEEVMIDIIDN
 1260- 1306 (31.06/20.43)	EAQLLYAARIilpfilkmsearekfkkdettKCVSALYDMIGKICSN
 1308- 1335 (22.39/12.41)	EVPLAYESLI..............cdimyfiKYI.FVGDVVRD....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05236 with Med23 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QQSYDYTNIKQENVENRAPQPNMQDFKPSQLQQQLQNPAMDIHMQQQGMHNFNPRTQNEMREEYANMMRNEATQIHMENQQKMSQMGMFPGQGANQQMNMTGVHQMHPGDPRFQGDMRMQQKFSQQHPMNMHPAMLNKQQPMSHQGGAGQAQPMNTFGNPPQYSNMMHQQGMPPYNQMMAGKQPQMMHPGRIPPNFNMASSINPYTNPQQFSNMPRHPNMPMQGNVPNPHGMAQPGMSPIYPQQSHMYQNMPNQSGFPMHMQGHGFNQQRM
1424
1694










Molecular Recognition Features






MoRF SequenceStartStop




NANANA