<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05228

Description Uncharacterized protein
SequenceMIDTKFRDELATKRERVELLYSFRGSKIGRGTYGHVYKATPRFETQENKGKIYALKLIEGNGISMSSCREIALLRELSHPNLIKLNRVFLSSERKVWLLFDYAEHDLWHIIKFHRNAKQKKQAVMVPKSMIKSLLFQILDGIHYLHNNWILHRDLKPANILVMGDDPYERGMVKVADMGFARTFHTPVRPLADLDPVVVTFWYRAPELLLGAKHYTKAIDIWAIGCIFAELLTSEPVFFCREEDIKASSPYHKDQLSRIFQVMGFPQDTDWPDLKKMPEYQRLTKDFKKQTFSDCELSKYLEKHKVKTNDRGFNLLQKLLTFDPIKRISSNDALNDIYFKESPKPTLDVFRGGPIPYPRREFMQDENEDKVIGKQQNVQLQQHMVNTIGTNKMFQQQRNNQISGNDIKSNKFQNISITNQIEFNSTNNLNQSLPQQTNTFNNGNHQNIRIQQNQYNPQMIFHGHDPNRVISQHEQSFTQVPIRVSNSQYVNQHQSHVNSQDHSRIMGQQIFSGYDQNRLMIQQQGQNNIIQIHPPNMQQHYIQSNQTASQQQMMQSQNFMWNQQQHYQ
Length568
PositionKinase
OrganismParastrongyloides trichosuri (Possum-specific nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Parastrongyloides.
Aromaticity0.10
Grand average of hydropathy-0.724
Instability index45.57
Isoelectric point9.33
Molecular weight66699.05
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05228
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     180.69|      35|      35|     448|     482|       1
---------------------------------------------------------------------------
  378-  432 (29.09/11.33)	VQLQqhmvntigtnkmfQQQRNNQ..ISGNDiksnkfQN..ISIT....NQiefnsTNNLNQS
  448-  482 (62.90/32.92)	IRIQ.............QNQYNPQMIFHGHD......PNRVISQH....EQ.....SFTQVPI
  497-  520 (25.00/ 8.72)	VNSQ............dHSRIMGQQIFSGYD......QNRLM.....................
  521-  553 (42.08/19.63)	..IQ.............QQGQNN..IIQIHP......PN..MQQHyiqsNQ.....TASQQQM
  554-  568 (21.63/ 6.57)	MQSQ.............NFMWNQQ...................QH....YQ............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     119.97|      27|      37|      98|     125|       2
---------------------------------------------------------------------------
   73-   97 (38.70/27.46)	LLRELSH.....PNL...IKLNRVFLSSERKVW
   98-  125 (43.62/38.28)	LLFDYAE.....HDLWhIIKFHRNAKQKKQAVM
  134-  163 (37.66/26.51)	LLFQILDgihylHNNW.IL..HRDLKPANILVM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.14|      23|      39|     191|     217|       3
---------------------------------------------------------------------------
  191-  217 (33.50/34.22)	LADL...DPVvvtFWYRAPELLlGAKHYTK
  228-  253 (37.65/24.54)	FAELltsEPV...FFCREEDIK.ASSPYHK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.37|      41|      76|     254|     294|       4
---------------------------------------------------------------------------
  254-  294 (74.52/45.89)	DQLSRIFQVMGF.PQDTDWPDL...KKMP.EYQRLTKD.FKKQTFSD
  295-  327 (33.02/16.50)	CELSKYLEKHKVkTNDRGFNLL...QKL......LTFDpIKR.....
  332-  369 (49.83/28.41)	DALNDIY....F..KESPKPTLdvfRGGPiPYPR..RE.FMQDENED
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05228 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FNSTNNLNQSLPQQTNTFNNGNHQNIRIQQNQYNPQMIFHGHDPNRVISQHEQSFT
2) VFRGGPIPYPRREFMQDENEDKVIGKQQNVQLQQHMVNTIGTNKMFQQQRNNQISGNDIKSNK
3) VPIRVSNSQYVNQHQSHVNSQDHSRIMGQQIF
423
349
480
478
411
511










Molecular Recognition Features






MoRF SequenceStartStop




NANANA