<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05221

Description Uncharacterized protein
SequenceMSDVTRKTDDIMPPPKQIPTSVADDSKFVKPTGIPQKGKKFIYVEPKKEWNVMEYGLEGSEALIPPKSYQENLAEKASRINWKKIVGSNVTYDDPEEITDIDSDRANDLVDRILALKMHKNLSVPAAYVPNSGSKLIVKQSDLIVKNGSGLNDDELERQRINMLHKEANEKGIMMDVDENDYEEMAKCVDDKYANPYSGPIVINDVNKMIENNRIYENLRNQKYIEGEIPIEKKKKPKDSNSDDEEIGYMIGKTAVESFKEGRIMQELEYNNALSSKRVIDDPVVTSKIRYILQKRLSKKSLEYHFYGRPLQGDDAKNIFQILNPSLGNTFGMLPSEIGNGDFDPTTSDGLVKQLTDRQLDIAKKAWDTLELPEFEFKILEQLKNDVQEAKERGEDVKTVAIHFGSSKYIIPVVTKDAFTTEPRKSDEMSSDSEDDEDDEAMDVDNKAPEEAEHHDSTAPVAFYINRNGKLLGCKIDGESYSLEKPESLGNEITHQILEAIESNDHKKESVSEDEDNDNRSSRSRSIAKEMEPQHRLPSPVIPEAGPWHKVAKNLHEALQNVNYLLDQLRVMDTPYLKPLTVAETSGDEKTATNSKLYLWVAKRKALEDAVSILDIGMKHRKVDTESFEDKQAFFNELKSMREFYRLRKVGKFLTGDLGYHNFSGKYKQEEAFDVVRKSSALLEEEKKQKNEIGDTSPLAYLQVTVPCDLMRRTVMSVDIIIDNVVEKDKLTKKDDSDLEYMVVKPEDTTKIHWRKALLWAQESLICRDIFKILFTNATEANDIFSTQRENVLLISLYSNVILKIQLDFYPFKDGELPQPGIPVLNQILRQLFLSDLCIRPKQLQQFITLPMVDTQDYISGKSFVDCNKTMLKEMAQFSRNTTLLSRICKVASHYRLLQEVIEVLEKFSIMYPDPSLTWNFFRITTIETHINVVLSNKGVDAVPKQQFSIVVTDDNAIITIRIKDGKDTFECFRDPLLLQSTLRVIYGKFIINTVALHSKQWVWFVLSSNLRFAESNNTEEGNLSLVLSNVSGLYHIYFTVNYKNLSKTVTLKKNIRGDNDSTSSSSDCDDEDDGDNKAKHFKLDYESLIGSTLLRKFDFLFAVFR
Length1106
PositionHead
OrganismParastrongyloides trichosuri (Possum-specific nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Tylenchina> Panagrolaimomorpha> Strongyloidoidea> Strongyloididae> Parastrongyloides.
Aromaticity0.08
Grand average of hydropathy-0.551
Instability index43.42
Isoelectric point5.27
Molecular weight126432.90
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05221
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     243.91|      75|     156|     800|     887|       1
---------------------------------------------------------------------------
  809-  887 (123.25/112.64)	FYPFKDGELPQPGIPVlnqILRQLFLSDLCIRPKQLQQFI...TLPMVDTQDYISGK.SFVDCNKTMLKEMaQFSRNTTLLSR
  970- 1048 (120.66/80.08)	FECFRDPLLLQSTLRV...IYGKFIINTVALHSKQWVWFVlssNLRFAESNNTEEGNlSLVLSNVSGLYHI.YFTVNYKNLSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     236.58|      76|     353|     154|     258|       3
---------------------------------------------------------------------------
  167-  246 (118.89/101.85)	EANEKGIMMDVDeNDYEEMAKCVDDK.....YANpYSGPIVINDVNKMIENNRIYENLRNQkyIEGEI..PIEKKKKPKDSNSDDEE
  434-  516 (117.69/56.78)	EDDEDDEAMDVD.NKAPEEAEHHDSTapvafYIN.RNGKLLGCKIDGESYSLEKPESLGNE..ITHQIleAIESNDHKKESVSEDED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.79|      32|     670|       3|      35|       5
---------------------------------------------------------------------------
    3-   35 (52.32/36.42)	DVTRKTDDIMPPPKQIPTSVADDS..KFVKPTgIP
  674-  707 (46.47/27.21)	DVVRKSSALLEEEKKQKNEIGDTSplAYLQVT.VP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05221 with Med17 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) TTEPRKSDEMSSDSEDDEDDEAMDVDNKAPEEAEHHDSTAP
2) YSLEKPESLGNEITHQILEAIESNDHKKESVSEDEDNDNRSSRSRSIAKEMEPQHRLPSPVIPEAG
420
481
460
546










Molecular Recognition Features






MoRF SequenceStartStop




1) KGKKFIYV
37
44