<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05160

Description Uncharacterized protein
SequenceMIDYAFKQELARSRENVDDLFYYDGHKVGRGTYGHVFKAQPKVPSAKYPAKEYALKLIEGQGFSMSACREIALLRELKHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHIIKYHRGAKAKKMPVMVPKGMVKSILYQILDGIHYLHSNWVLHRDLKPANILVMGDAPGVHRGRVKIADMGFARIFYNPLKPLAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPVFFCKEEDIKAQSPYHYDQLKRIFTVMGYPQESEWTDFKKMPDYHKLQTDIKSSQTAFPNCSMTRYMEKHKIESDSPQFKLLVKLLTMDPNKRISCKEAMEEPYFKMDPKPTEDVFYKFEIPYPKHADIKKSLAMNIVDDQNQQATNPQVNQAMNQQLDSEPVNKRLRMGGQQVDLVLWSF
Length418
PositionKinase
OrganismHaemonchus placei (Barber's pole worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Strongylida> Trichostrongyloidea> Haemonchidae> Haemonchus.
Aromaticity0.11
Grand average of hydropathy-0.406
Instability index55.23
Isoelectric point8.88
Molecular weight48612.97
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05160
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.59|      19|      89|     231|     252|       2
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  231-  252 (30.74/27.56)	ELLTAEP..VFFCKEEdikAQSPY
  321-  341 (31.85/19.83)	KLLTMDPnkRISCKEA...MEEPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.33|      27|      36|     122|     157|       3
---------------------------------------------------------------------------
  122-  157 (40.58/53.30)	MPVM.....VPKGMVKsilyqILDgihyLHSNWVLHRDLKP
  160-  191 (41.75/28.63)	ILVMgdapgVHRGRVK.....IAD....MGFARIFYNPLKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      29.34|       9|      23|     282|     292|       4
---------------------------------------------------------------------------
  282-  292 (11.91/15.38)	HKLQTDikSSQ
  307-  315 (17.42/12.57)	HKIESD..SPQ
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05160 with CDK8 domain of Kingdom Metazoa

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