<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05159

Description Uncharacterized protein
SequenceMGVSWVFEHDKTAKEVERLLEGGGAEQIGTYTVDCLPYTPNDKVEYEPSQVAAQSAHMMTEMMQMFFPLYHILKMTSSNPMWRVVFEHIDEFRASVNRHCSHLESWQIMSYTVATCFFIMWIRRINHSDKPFFQRARSSIYSIIRSLPWVKRRVKADLERARREIEEEVHQYDQKRDFYKFLPEHPLGGEELLSEARQYAAMGERRYMEHYDPRTRNQDLSLCAKIYDLFSHSDPHRSDAFPGARKMEAEILRMCLSMFHGGQEACGVVAGGGTEVMLLACLAYRNRGIARGMYHPEIVAPSTAHPALDKAAELFGMTIRRVPVREDDRVHAAAVKRAIGPHTCMIVASAPNHTTGTVDPIERLSEIAQQFGVPLHVDCCLGGFLLPFMEYCDYSIPTFDFRLPGVTSISIDLHRYGQAPRSCSVLMYRDQSMLRHQCFCNSDWAGGVYATPTLAGGRDGGAVATAWATLLGKGRDGYITACHRVVETTRRLADLLSDIDGITLRGAADLCIVAFETTLGDIYVLVDFMTTKGWHVDPLLSPEAARVPITLRMCEEGVLEAFVEDVIEGLRYLGENPTKTTKTSAFYHMLQTVADRSLVDELSLIRLQAHYSIPPPLDREHRSVRALSEYGRKMSTLEREGLTKEKLSAEKAQ
Length653
PositionHead
OrganismHaemonchus placei (Barber's pole worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Strongylida> Trichostrongyloidea> Haemonchidae> Haemonchus.
Aromaticity0.09
Grand average of hydropathy-0.249
Instability index49.60
Isoelectric point6.24
Molecular weight73868.80
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
carboxy-lyase activity	GO:0016831	IEA:InterPro
pyridoxal phosphate binding	GO:0030170	IEA:InterPro

GO - Biological Process
carboxylic acid metabolic process	GO:0019752	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05159
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.16|      32|      78|       5|      36|       1
---------------------------------------------------------------------------
    5-   36 (59.53/40.99)	W..VFEH.DKTAKEVERLLEGGGAEQIGTYTV.DCL
   82-  117 (51.63/34.59)	WrvVFEHiDEFRASVNRHCSHLESWQIMSYTVaTCF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.58|      15|     297|     226|     255|       3
---------------------------------------------------------------------------
  232-  251 (19.82/32.66)	HSDPHRSdafPGARKMEaeI
  535-  549 (27.76/ 7.76)	HVDPLLS...PEAARVP..I
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.27|      12|     253|      46|      57|       4
---------------------------------------------------------------------------
   46-   57 (22.42/16.08)	YEPSQVAAQSAH
  294-  305 (23.85/17.60)	YHPEIVAPSTAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.24|      29|     253|     131|     160|       5
---------------------------------------------------------------------------
  131-  160 (47.68/35.12)	PFFQRARSSIYSIIRSLPWVkRRVKADLER
  387-  415 (55.55/36.60)	PFMEYCDYSIPTFDFRLPGV.TSISIDLHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.74|      32|     183|     257|     288|       8
---------------------------------------------------------------------------
  257-  288 (60.23/35.30)	SMFHGGQEACGVVAG...GGTEVMLLACLAYRNR.G
  442-  477 (49.51/27.83)	SDWAGGVYATPTLAGgrdGGAVATAWATLLGKGRdG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05159 with Med20 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) TKEKL
643
647