<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05142

Description Uncharacterized protein
SequenceMATGSQLQPSAVSAFPQPPEYAKQYTDENIEKKTVLPPPPVPNEFTVFGEDYDFDEEVVRTLQSQKLQQLYSNTANWREELKKLNRSAVAAFLDLLDILIRCPSHPERHEKLQNLRLLFINMHHLINEYRPIQARDTIQTIMKAQIESINEVTIRLRDFLDAGRRLLNECYGEMRCFADTVEVNPVLMTDVGSERFDEVSENLRRFAEEANKPKEARFSAEERWEALKMDMAVYVTLVRFYVLLTLMYGKNVWVVVHSVVVNFLWVFRMTESCAVPQEATEMMARFERTGVRRGLMCTECHKYFRSREELFIHAEGCLLEAFESEVVTVFSDMPLLKVPPPAIGPVPSGITVKSDNLSGPPHLDPEHGQSVVILPSTSSHKSLQNVGSSEDSGLAGPPPKLSRYQTDSLEAEEIRSPIAYETLDLKWVLFSASTSVAETSNARTIESSNGLRLLVSVEKPPVFHESIDDFPDEDSDDPGEEVDEDVTTIGFGILVIFSEMPVLLLYHLFFFFGNLILYFTGTEKRLQNFSATSGSPILGGISGKVIGALANADDDPYRPKMECPTCGLILYRHNFSTHYRIHTGEMPFACQFCSKRFRTTSALKVHIRAHTGEKPYCCPKCTYSSITKRNLDRHIINNHIREGERRGPRQRKSRYRDDTDEYYTFGELAESMDGDPVDHHYILLGDNVFVSILQSSLLGGPRDDGVVVQRLNDDEEVEIYGAAELERI
Length728
PositionMiddle
OrganismEnterobius vermicularis (Human pinworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Oxyuridomorpha> Oxyuroidea> Oxyuridae> Enterobius.
Aromaticity0.09
Grand average of hydropathy-0.335
Instability index58.77
Isoelectric point5.19
Molecular weight82635.74
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05142
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.16|      23|      25|     571|     593|       1
---------------------------------------------------------------------------
  571-  593 (49.01/34.60)	YR..HNFSTHYRIHTGEMPFACQFC
  597-  621 (41.91/28.49)	FRttSALKVHIRAHTGEKPYCCPKC
  632-  644 (17.24/ 7.27)	DR..HIINNHIR..EGE........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      58.81|      13|     357|      28|      40|       3
---------------------------------------------------------------------------
   28-   40 (23.78/11.70)	ENI...EKKTVLPPPP
  366-  378 (18.03/ 7.31)	EHG...QSVVILPSTS
  384-  399 (17.00/ 6.53)	QNVgssEDSGLAGPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.62|      25|      25|     668|     692|       4
---------------------------------------------------------------------------
  668-  692 (45.09/23.96)	LAESMDGDPVDHHYIL..LGDNVFVSI
  693-  719 (37.54/18.91)	LQSSLLGGPRDDGVVVqrLNDDEEVEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.20|      26|      26|     153|     178|       5
---------------------------------------------------------------------------
  153-  178 (47.48/28.60)	TIRLRDFL..DAGRRLLNECYGEMRCFA
  180-  207 (38.71/22.08)	TVEVNPVLmtDVGSERFDEVSENLRRFA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05142 with Med7 domain of Kingdom Metazoa
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