<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05130

Description Uncharacterized protein
SequenceLKINFSVEKGNNSDTAVKLRHLEASLEQLKDSIESIVDISRDENYQSAKIASLKSQLQLKDSLITSFKKDGCPSDQVKEKRTKLVCVRCKCVIIDSNSTKFTNDKPFDLPKCEMKNSVDIEKEMIMHWYIVESLFEFDNIGVTNPDGGVKYLACSECEYGPIGFYCNDALHYYLAAERICLSNC
Length184
PositionMiddle
OrganismDracunculus medinensis (Guinea worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Dracunculoidea> Dracunculidae> Dracunculus.
Aromaticity0.08
Grand average of hydropathy-0.353
Instability index38.89
Isoelectric point5.47
Molecular weight20856.63
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05130
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.87|      21|      25|     133|     157|       1
---------------------------------------------------------------------------
  137-  157 (41.68/24.92)	FDNIGVTNPDGGVKYLA....C.SEC
  159-  184 (35.19/13.18)	YGPIGFYCNDALHYYLAaeriClSNC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.46|      23|      29|       9|      36|       2
---------------------------------------------------------------------------
    9-   33 (30.03/32.78)	KGNNSDTAvKLRHLEASLeQLKDSI
   41-   63 (38.44/21.52)	RDENYQSA.KIASLKSQL.QLKDSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.61|      10|      31|      65|      75|       3
---------------------------------------------------------------------------
   65-   75 (14.81/12.34)	TSFKKDGcPSD
   99-  108 (19.80/10.28)	TKFTNDK.PFD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05130 with Med9 domain of Kingdom Metazoa
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