<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05122

Description Uncharacterized protein
SequenceMSNAVEVSGITGFQPSESAVGNEAEKLQAIIMNHVDSVQMREMFWNISRNVDMEEVTCNEAIKLLKTMTDEEKTQCCKSALNLLSNKDDPRYVHIERMLSAIFIAACNAGTLSLSECCELLILNTNFTLSTPLDTQKFEYMQKNLHLIDYKGLRNLLKLLVVERMQEIPPTITHSHRQMLLPVENMLLTMIDRKLNLLPCLFTITELHRVSNNSRAFLLPRVAKKFNEMFISFRPLTEMVTVIGRPWLFPLSAHVSYPSSASSWKLEIVTFRLHQRAHLPYKSELFAPQSSLLYTLIRQPRGKDAISHVMRQSTNVSPQRIQCDELLHMIILEAMSEMEKTEIRLDDPANQYQWMNVTHTVTFTLLHGNASFSRLLKMLYESLIETIYRKGRNELMWVILQYVAVYIAKVSNEDMMRIADIYSLLYSDEQTWSGADTDPLLFVRFLVPAAIWIHFYKKLGNQTDLLPKPSESLFRQIQFLQERTADSDPAIQNVADHNAVLAAVANAYSNDMPNFQKFVLSAVDIFLDGSGDDVGRLPYGVLCYPKKIPLPLPLIDSLTFHARSHLFQLCMVKITTLLSVQHNLKYPSPASIDTLVRLAATTEFEYGVKQLLSLMAKALTTITTNANMNPNSHTDRSRELLFILCEILSYRLIIYPVPAYSKVSVILQCYSAISCPQVQMNHTLYSSLEQVLLRYWLWNTPSELSVMCSVLFGKQGKFTALINSPNSFYEPQHISTVVHERTHSLHMSPEVLRYILLSLFRGLKMTGIEMPSEVLQRCNANFSWPASISRTFSGQIFGCTIDEGTDTTHLEELLHCVHQDVRHTQDFLFNQAITPEEQLIKFFTVEKRCTLFCVLYNIVYETKKVHPVFYGILGSLNAKEIIIMVNKFVDYFVYLLKKNLPEDSAFTAMVSVLNDMIFSFHLIPFDRLLISLVLHPTDDRSSEIAFLIIHSLVSTFPDLRARMAAISHYIPSNKIINTNLSYFNKLNEFYSQHPELTYRELELKLRREMQMEMGMRPMESTIISECHMPIYYSNIVERMLPVIDVLLMRAFEPVVSDQLFSSLLMGFKSAYRFHPQPTMFMYHVLYTHDKCMTLAGRARLFVSEICGQLEDKFSSILHRLLTFINPIYKNVLSDTKFAIVSPAFMNDNYQLIMPSQLCQTLVDRIIQSCFYAHQPPSFVCKDWRFAEMPPASQTLLGACIEILASPHPPNVITRALIDTVFVRPLHQPYATINTVALILTSLPSPYQSVFYEHIVSVLDSETLLQADPSICFDTLENECFLLTESQLLTNIALGHAYLQHCNTSALGALPEFVREQLAPKLITEAQLIFVLRLVVPILQRFYDAKERSKQIQDLAIDIYKMTVKVNEQVGTLQYEDSVCDLLYHMKYMYVGDFVKNEAEQAIQRLSPSMQEKLKYISHSQSNTSDFFHAWIKMPSKQADISFAQAMRSIRQCPWYWGNLTWIESELLLNHSQPGSYLIRDSASDRCIFTLSYRTEKSVHHTRLPQYGGLFCLGGLRISCIFGNFILLWVLLYLCGSRCSPNSLVKAKTLRAFVEEAIKSCEKRGICMLMHTKGDRSATENVALIRPLQRHEFLPPLKYLCRLVIRHSANPTALSSLPLPPTMLNYIQDRRYILPPFVLELR
Length1641
PositionTail
OrganismDracunculus medinensis (Guinea worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Dracunculoidea> Dracunculidae> Dracunculus.
Aromaticity0.10
Grand average of hydropathy0.026
Instability index48.10
Isoelectric point6.93
Molecular weight188310.07
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process
intracellular signal transduction	GO:0035556	IEA:InterPro
negative regulation of signal transduction	GO:0009968	IEA:UniProtKB-KW
regulation of growth	GO:0040008	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05122
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     122.96|      32|      35|    1142|    1176|       1
---------------------------------------------------------------------------
 1142- 1173 (48.06/35.24)	................PafMNDNYQLI...........MPSQLCQTLVDRIIQSCFYAH
 1175- 1207 (29.84/16.07)	PP.........................sfvckdwrfaeMPPA.SQTLLGACIEILASPH
 1208- 1253 (45.06/23.07)	PPnvitralidtvfvrP..LHQPYATI...........NTVALILTSLPSPYQSVFYEH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.58|      12|      35|     171|     182|       2
---------------------------------------------------------------------------
  171-  182 (23.15/16.10)	TITHSH......RQMLLP
  203-  220 (14.42/ 6.66)	TITELHrvsnnsRAFLLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.12|      19|      35|     859|     877|       3
---------------------------------------------------------------------------
  859-  877 (34.75/26.77)	VYETKKVHP...VFYGILGSLN
  893-  914 (27.37/19.18)	VYLLKKNLPedsAFTAMVSVLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.22|      11|      21|     249|     259|       4
---------------------------------------------------------------------------
  249-  259 (20.91/12.04)	FPL..SAHVSYPS
  271-  283 (16.30/ 7.52)	FRLhqRAHLPYKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.77|      31|      39|    1264|    1300|       5
---------------------------------------------------------------------------
 1281- 1317 (40.48/35.02)	LLTESQLLTNIALGHAYLQH..........................cntsaLGALPEFVrEQL
 1321- 1382 (35.29/11.42)	LITEAQLIFVLRLVVPILQRfydakerskqiqdlaidiykmtvkvneqvgtLQYEDSVC.DLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.15|      15|      40|     651|     669|       6
---------------------------------------------------------------------------
  651-  669 (18.15/18.77)	RLIIYPVPaySKVSVIlqC
  694-  708 (32.01/16.44)	RYWLWNTP..SELSVM..C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.02|      28|      40|     542|     569|       7
---------------------------------------------------------------------------
  542-  569 (51.70/36.06)	LCYPKKIPLPLPL.IDSLTFHARSHLF.....QL
  578-  611 (37.31/23.60)	LSVQHNLKYPSPAsIDTLVRLAATTEFeygvkQL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05122 with Med23 domain of Kingdom Metazoa
Unable to open file!