<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05096

Description Uncharacterized protein
SequenceMGGDALEELLVCEGWPINGKQLSNFIGESISKIQDANQLKKQLLDADLREYAVPLLSDRINKQLGEFKGPLVVQVVKQRNVSYPKYNEITHTDGLIKIQLSDGFSSIQALLFEPIPKLNAETPPGTKVCLAGKIPIENGMLLINETNCQVLGGNVEKMIEKWNMEKNWQQKPIRNIESNAPKWTQFSKQRLPQSCLPVNATNEMFRANDIISGLNKKMIDERGDDFSAARKAQIDHVIENNAIKKFARSQLKPKPLENCASTSCNNNSKKDPVIKGKPDTENMDRRSFRDDKKNLLPVHRPSNPPTLYDFMQSKVPIPDGISTGYQNFGNLQFPMEKIETNQQSVETQGMDRPRRGRFNERGFRYQQTDDNTNGSHIIEISNSNRYRKHCNWRLEREKNYATNMVNDKVRVNHADDQLVSTANKELSALHLSSIDNGPLGVGKVHDVPQETVCFENKNHGYQQYAVHGPVYKQQQQQQRQQQRQQYQQQQHQQQYQQQYQQQQHQQQYQQQYQQQQQRQQQQQQQQQSFDNRMMNGGMLPVWKIGDKCLAPWSDGQFYPSTLVSMGPADMCTIEYDEYGNRSSVPVGRPVRTYMKLMISRHASTAARVIKGAIRRDMPSKIALWLTPEAVKRVKYLLSKQPETTALKISVRQRGCNGLTYTLDYAQQKAKFDEEVVQDGVRLWIDPKAQLSLLGSEMDYVEDRLSSEFVFRNPNIKGTCGCGESFSI
Length727
PositionKinase
OrganismBrugia pahangi (Filarial nematode worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Spiruromorpha> Filarioidea> Onchocercidae> Brugia.
Aromaticity0.07
Grand average of hydropathy-0.843
Instability index48.05
Isoelectric point9.02
Molecular weight83351.24
Publications









Function






Annotated function


GO - Cellular Component
cytoplasm	GO:0005737	IEA:InterPro
nucleus	GO:0005634	IEA:UniProtKB-KW

GO - Biological Function
iron-sulfur cluster binding	GO:0051536	IEA:InterPro
RNA binding	GO:0003723	IEA:InterPro

GO - Biological Process
iron-sulfur cluster assembly	GO:0016226	IEA:InterPro
mRNA processing	GO:0006397	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05096
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.32|      20|      40|     461|     490|       1
---------------------------------------------------------------------------
  461-  489 (33.55/25.74)	YQQYavhgpvYKQQQQQQRQqqrQQYQQQ
  492-  511 (43.77/16.17)	QQQY......QQQYQQQQHQ...QQYQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.19|      16|      16|     301|     316|       2
---------------------------------------------------------------------------
  301-  316 (31.43/18.02)	PSNPPTLY.DFMQSKVP
  318-  334 (26.76/14.38)	PDGISTGYqNFGNLQFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.78|      14|      22|     240|     255|       3
---------------------------------------------------------------------------
  240-  255 (20.63/16.72)	NNAIKKfaRSQLKPKP
  265-  278 (26.15/14.21)	NNNSKK..DPVIKGKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.43|      18|     138|     524|     542|       4
---------------------------------------------------------------------------
  524-  542 (31.27/22.19)	QQQQSFDNRMMNGGmLPVW
  666-  683 (32.17/17.82)	QQKAKFDEEVVQDG.VRLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.55|      15|     142|     220|     239|       7
---------------------------------------------------------------------------
  220-  239 (19.26/29.13)	DERGddFsaaRKAQID......HVIE
  359-  379 (24.28/15.83)	NERG..F...RYQQTDdntngsHIIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.52|      13|      18|      38|      55|       8
---------------------------------------------------------------------------
   38-   55 (16.73/23.67)	QLKKQlldadLREYAVPL
   59-   71 (23.80/16.16)	RINKQ.....LGEFKGPL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05096 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ATNMVNDKVRVNHADDQLVSTANKELSALHLSSIDNGPLGVGKVHDVPQETV
2) FGNLQFPMEKIETNQQSVETQGMDRPRRGRFNERGFRYQQTDDNTNGSHIIEIS
3) KPLENCASTSCNNNSKKDPVIKGKPDTENMDRRSFRDDKKNLLPVHRPSNPPTLYDFMQSKV
4) YAVHGPVYKQQQQQQRQQQRQQYQQQQHQQQYQQQYQQ
401
328
254
464
452
381
315
501










Molecular Recognition Features






MoRF SequenceStartStop




NANANA