Description | Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MADESQQRAVNTAFAPPPPLWKHFTRENIDKVEQIKAEAFKKEDGRSNKNKQWSSAELRALELPSELRYLVPPDVPEGQYSVFGELQTMSTTLPSLQEQGIEQLYPEPAAAGTEQNSQPSPPLNHAYYLLKISKSLLLNFLEFTGILSVSPEQFESKVEDLRNLFINAHHLLNLYRPHQARESLIMMMEEQLNHSREEMRQMDKVKAEVESVLEQLQAEGNRVSATGSEDDTDQAKALKEKADEHSRLIWDLLDKEN |
Length | 257 |
Position | Middle |
Organism | Penicillium nordicum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Penicillium. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.733 |
Instability index | 56.86 |
Isoelectric point | 4.96 |
Molecular weight | 29383.61 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364060 ECO:0000256 ARBA:ARBA00003669 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP05064 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 43.07| 13| 179| 26| 38| 1 --------------------------------------------------------------------------- 26- 38 (21.73/14.26) RENIDKVEQIKAE 196- 208 (21.34/13.88) REEMRQMDKVKAE --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) ALKEKADEHSRLIWDLLDKE 2) PLWKHFTRENIDKVEQIKAEAF | 237 19 | 256 40 |
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