Description | Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MASQDASMEEILWRSPPHVQMMGGFLHSNNILFYFAESPFFDSTSNNASLAIQANYNDAFRHFVETREAFEARLKTMQGLEFIVSYDPLQAAAQTDNRFAHEPSNIWVIRKQNRRKRSGMDDEVTVISTYFIVGDCIYMAPSVASVVGNRILSAVTSLTQLMKSAATLPTFTASHGHTYLPPGVRSKEGAGTSQASQSKEATPMPDVSFPTTEFSQSTSKSSLGGSTASSNYQDTRSLAESFSLLTRYGDEFMDESPLVGEPGSFILSRTGGEPTGSAVKGAPKVAVNAAPTGTPSALPVRASTPQVRVDTPSKVSEKSSPPSSTGDRGKKKKSRIVS |
Length | 338 |
Position | Head |
Organism | Penicillium nordicum |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Penicillium. |
Aromaticity | 0.08 |
Grand average of hydropathy | -0.384 |
Instability index | 53.14 |
Isoelectric point | 7.83 |
Molecular weight | 36430.30 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR013286 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP05062 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 60.02| 19| 20| 232| 251| 1 --------------------------------------------------------------------------- 232- 251 (29.57/24.72) YQDTRSL...AESFsLLTRYGDE 252- 273 (30.46/20.07) FMDESPLvgePGSF.ILSRTGGE --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 46.07| 15| 16| 295| 310| 2 --------------------------------------------------------------------------- 274- 288 (24.58/12.14) PTGSAVKGA.PKVAVN 295- 310 (21.49/14.21) PSALPVRAStPQVRVD --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 91.84| 29| 33| 165| 196| 3 --------------------------------------------------------------------------- 165- 196 (43.20/35.52) AATLPtfTASHGHTYLPPGVrSKEGAGTSQAS 201- 229 (48.64/28.61) ATPMP..DVSFPTTEFSQST.SKSSLGGSTAS --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) SLLTRY 2) SSTGDRGKKKKSRIVS | 243 323 | 248 338 |
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Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab