<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05060

Description Uncharacterized protein
SequenceMPEPGSAAPQAYSLSAPDWRPAWHHRDQLGTPGLRTAPTHTIVGPYAARAGAPFVSPVPVDVGSSADLWYTRLSRDSVRTLLGDMVDAIRTRRRHGAPTPIRDLAACDMPTRVTLPDAHLDTFVRALADPAQPLSVLAQAVPHGFRGERLLDMLWQGCVPGLPRARSVPLSRALWLIQVVGASDLQAGRARGLTPLAYTYEWTDNVLAWLASMLTHAPFTPEERATWTARWRYAMRLIDTLLSQSLLVPYLYYAWLVESLPRAPGNTRACLLQQVARHYKSICAHTALASGLVGALRTMADSKTSTESVSGTVSWLREQAQDLLRRCVMLAPTTVWVHPACIALGMLPAIPDFERAKATSQALRTALAAYLDGVDAWDAACWRQLDDNQTGSTALFVEYFLPRHASAPMARRRLHSLCTWACTLHRVGVHRLYVAAALAHLLDECQAQRLLLPDGRRLSCPWPPFSLSEAVMQWLDTLSESVPLRPAYVARLFGLFARDGVLSYPYFLQRLMARGWIRASGDTRTQRHTTHIHMRLLRSMPVPPVSVNMQQQRRFAIYGARTSESYEEATERRALRELKRVLEWATDDPSTLSAPATPSAAPSSPLPSSPIALASPRSTPAVTAPTSTATFHMADTLQWPTRAPHVWAASPYIQARLVERITPMLLHEVPTMPADRFVLVATLLTSMHAMDTLGRMVCALLDGHDLACLVPVCHIVATYARVWDALDMAILMAERLAPYAFGEASVLPGAPRVLPLVGRGMVVPMARTALTALGALDVPVATYAPMPMADVSVPSCATDEATRIVYTLLHDPWPADDLCLPLISAYSLEQATTLLVRAAFTALTSTDMVVPMTLVTCLATLAGTAGIKLDTVIHTCIRTVWDGPSTGALTWTALVVHLVTFGLVDASTLLQDVLAPFIATAPRTHHGWPACRELVYAIAATTSQAGHVCSMPTLGEATWFALHMQQQRLPLRDGLLPLLSAMDACDVPAHDELVMAVQPHTRTWFAQWLAHPDVVWSQVRTWPADTRMQKWTRLVAWLEPEVVWDLQSASHGALSLLPWRLQWDTEAWPSSFFATCLEMPAELGGSPMDVLLQWDAPPSLWEAAQRWALEAWVHALDAQHGHAQTQAIHALARLVHAAFTNESAVPSSTWPRHSAYALRVLERFAQAWSSATPALVRYAGTLCLLHSTSLTHSAWPTILTHLVQEPSHAWVLPVTTYVMAHMDSTKLVAWLRAQAQTSAVVSSWAKPLLHYQGVPPTPSHLPSPWHRRDACLPSKDALATSAQTTSRDPWDVPLSLPSTIPCAPFTPQTTREWMLVDAPDAPWTHLPSERSYGDGDDAASIYPRMTGATFKRAHTSPTRSMKRMRTY
Length1367
PositionKinase
OrganismMalassezia pachydermatis
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Malasseziomycetes> Malasseziales> Malasseziaceae> Malassezia.
Aromaticity0.08
Grand average of hydropathy0.026
Instability index50.51
Isoelectric point7.83
Molecular weight150567.75
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05060
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     207.87|      43|      43|     842|     884|       1
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  684-  725 (38.20/13.41)	.LTSmhaMDTLGRM.....VC.AL..L....DGHDLACL.VPV...CHivaTYAR.VWDA.
  755-  801 (46.08/17.66)	PLVG...RGMVVPMarTALTALGA..LdvpvATYAPMPMaDVS...VP...SCAT...DEA
  842-  884 (79.13/35.48)	ALTS...TDMVVPM..TLVTCLAT..L....AGTAGIKL.DTV...IH...TCIRTVWDGP
  888-  929 (44.45/16.78)	ALTW...TALVVH........LVTfgL....VDASTLLQ.DVLapfIA...TAPRTHHGWP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     246.16|      40|      43|     984|    1023|       2
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  949-  977 (26.72/ 7.46)	.....................C.SMPTLGE.........ATWFAlhmqqQRLPLRDGLLP
  978- 1017 (71.89/33.30)	LLSAMD.........A.....C.DVPAHDELVMAVQPHTRTWFA.....QWLAHPDVVWS
 1018- 1045 (48.33/19.82)	QVRTWP.........A...........DTRM....QKWTR..LV.....AWL.EPEVVWD
 1064- 1102 (48.45/19.89)	DTEAWP.........SsffatClEMPAE....LGGSPM..DVLL.....QWDAPPS.LWE
 1103- 1151 (50.77/21.22)	AAQRWAleawvhaldA.....Q.HGHAQTQAIHALARLVHAAFT.....NESAVPSSTWP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      83.07|      18|      43|     208|     225|       3
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  162-  175 (20.10/ 6.78)	....LPRARSVPLSRA............................LW
  210-  255 (19.99/ 6.69)	LASMLTHAPFTPEERAtwtarwryamrlidtllsqsllvpylyyAW
  256-  269 (20.37/ 6.98)	LVESLPRAP..GNTRA..............................
 1296- 1309 (22.61/ 8.70)	LPSTIPCAPFTPQT................................
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.13|      39|      43|     591|     633|       4
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    2-   39 (34.01/10.05)	....PE.PGSAAPQAYSLSAPDWRPAwhHRdqlGTPGL.rTAPT...
  591-  629 (68.11/35.39)	TLSAPA.TPSAAPSSPLPSSPIALAS..PR...STPAV..TAPTSTA
  636-  674 (55.01/19.73)	TLQWPTrAPHVWAASPYIQARLV.....ER...ITPMLlhEVPTMPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     186.13|      59|     232|      62|     138|       5
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   69-  133 (85.76/65.62)	WYTRLSRDSVRTL.....LGDMVDAIRTRRRHgAPTPiRDLaACDMPTrVTLPDA...HLDTFVRALadPAQP
  420-  486 (100.38/38.76)	WACTLHRVGVHRLyvaaaLAHLLDECQAQRLL.LPDG.RRL.SCPWPP.FSLSEAvmqWLDTLSESV..PLRP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     184.46|      57|     912|     313|     378|       7
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  313-  378 (92.16/57.24)	VSWLREQAQDllrrcvmLAPTTVWVHPACIALGMLPA...IPD.FERAKA...TSQALrtALAAYLDGVDAWD
 1228- 1291 (92.30/41.71)	VAWLRAQAQT.......SAVVSSWAKPLLHYQGVPPTpshLPSpWHRRDAclpSKDAL..ATSAQTTSRDPWD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.95|      20|     102|     185|     206|      12
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  186-  205 (37.71/27.85)	QAGRARGLTPLAYTYEW.TDN
  568-  588 (30.24/10.49)	EATERRALRELKRVLEWaTDD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05060 with Med12 domain of Kingdom Fungi
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