<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05036

Description Serine/threonine-protein kinase SSN3
SequenceMKRNTQAALEDEHGRSTGYTPKVRVTERYRIIGFISSGTYGRVYKAISRVGPNGSGVAAMKTSSGTVSSANAGGAEVAIKKFKPDKEGEQITYTGISQSAIREMSLCTELSHANVIRLVEILLEDKCIFMVFEYAEHDLLQIIHHHTQQPRHPIPPTAIKSIMFQLLNGCQYLHTNWVLHRDLKPANIMVTSAGEVKIGDLGLARRFDKPLHSLFSGDKVVVTIWYRAPELILGSYHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKMVPFQRNQMQKIVETMGMPTKDRWPLLPSMPEYHQLSTLQPMLPGNSGSSHHGGQQQQHHHHHHSHGHHGPHPHRYPTTSVLEKWYQNTVSNNSGAGTAANAPNGAPALASLGQEGYRLLSGLLEYDPVKRLTAAAALQTPFFSTGDRVSVNAFEGLRTEYPPRRVSQDDNDIRAGSLPGTKRTGVQDDTLLRQAKRVKE
Length472
PositionKinase
OrganismEscovopsis weberi
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Hypocreaceae> Escovopsis.
Aromaticity0.07
Grand average of hydropathy-0.451
Instability index35.40
Isoelectric point9.27
Molecular weight52442.11
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05036
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.48|      21|     186|     144|     165|       1
---------------------------------------------------------------------------
  144-  165 (39.61/26.84)	HHHTQQ....PrHP..IPPTAIKSIMFQ
  333-  359 (34.87/18.88)	HHHHSHghhgP.HPhrYPTTSVLEKWYQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.08|      10|      15|     297|     306|       2
---------------------------------------------------------------------------
  297-  306 (21.58/14.46)	PLLP..SMPEYH
  313-  324 (16.49/ 9.11)	PMLPgnSGSSHH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.56|      16|      16|     427|     442|       3
---------------------------------------------------------------------------
  431-  446 (29.80/21.59)	TEYPP..RRVS.QDDNDIR
  447-  465 (16.76/ 8.88)	AGSLPgtKRTGvQDDTLLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.64|      21|      33|     179|     199|       4
---------------------------------------------------------------------------
  179-  199 (35.78/23.69)	LHRDLKPANIMVT...SAGEVKIG
  211-  234 (29.86/18.73)	LHSLFSGDKVVVTiwyRAPELILG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05036 with CDK8 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AFEGLRTEYPPRRVSQDDNDIRAGSLPGTKRTGVQDDTLLRQAKRVK
2) STLQPMLPGNSGSSHHGGQQQQHHHHHHSHGHHGPHPHRYPTTSVLEKWYQNTVSNNSGAGTAANAPNGAPALASLG
425
309
471
385

Molecular Recognition Features

MoRF SequenceStartStop
NANANA