Description | Mediator-rna polymerase ii transcription subunit 21 |
Sequence | MGDRLTQLQDAVDQLAQQFVACLHYVNKRHDLEILSPNDKIREVKDIPKEVDSLPPDEFRAGMVELSQDLIVKEQQIEVLISSLPGLDNSEMDQERYIKELEEDLKVAEAQRQEAIKEKDQILAELDGVIRSIRRP |
Length | 136 |
Position | Middle |
Organism | Fusarium langsethiae |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Hypocreomycetidae> Hypocreales> Nectriaceae> Fusarium. |
Aromaticity | 0.03 |
Grand average of hydropathy | -0.582 |
Instability index | 60.39 |
Isoelectric point | 4.58 |
Molecular weight | 15662.58 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669 ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP05015 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 40.28| 12| 34| 65| 76| 1 --------------------------------------------------------------------------- 65- 76 (20.53/12.31) ELSQDLIVKEQQ 100- 111 (19.75/11.63) ELEEDLKVAEAQ --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 37.61| 13| 36| 3| 15| 2 --------------------------------------------------------------------------- 3- 15 (21.68/14.79) DRLTQLQD...AVDQL 39- 54 (15.93/ 9.09) DKIREVKDipkEVDSL --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) LIVKEQQIEVLISSLPGLDNSEMDQERYIKELEEDLKVAEAQR 2) VELSQ 3) VKDIPK | 70 64 44 | 112 68 49 |
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