<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05011

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMCNLLTSAMETKVTSKTSSLKALLLRAWRERWSDLQWGINIKTILPRGVSGDVYNLADCILQQALVGLGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCILSLLEFLESIQVGITCRGKPEEDLLAAAVLSIVHWLLQCYLHTLTKMPQNSPLTPQPTELMDKPASILKQMLNSDFLCAMMYLAKYDDKDLYIEVVKKCQEIETLLKTSSLKSSVPIEESLKKLCNLEVDCLTLSPEMSQMESITHCLQPLFAVQVLQNPSTETSVFVNQMLMVQRLKNYTNARLYCEIIRACLMCLHNVTSTFKESQWGAFTFLKVPLILKELHAVHTNGDDKLEYSQDILDAFELLLQFTPLLDIVDTACSCNSVECLLNALQKVNLVTEKQTKQLSSRREGVTATLQKLESSTSTSSIPKVIVRAEPTLSGILKTLNADYTKIHEALLSMLYQVLTGKSFELMLAVATVEGKLKTFVTKLIKFNECSKQINEPVPPKTAATRAMLFDISFLMLCSIVQTYGSDAVLEEGEGDSFFEQWVRECMPERNQPKSPQKMLQNVDPARVDALLAQINSPDSDLKSSNIKWHIACQSAMGAVKELLCAWESDVLGASDVKRALDGLRTTACCLPVCAAAWLCAYMSITHQDALLKPLNMVQHFLTPLPGDEVQDNLKERSSLMSQIIRKMQYDVHPPTQSKTKVLSMSHSIISRQPILEQLENEWGNINQRGWINIQATQSLESLLNTGGSLWFVTNIVKEVLKYRYQEELDQAVDLAFSIFHLNIENCTLDLINYIIPQYLYNSLQSEELVEPQSSVLAKLCVYCIFSTLEHNNSNPSRGNSRKRVRRDLDAEELDALGVPANKILRLNETGDSNTIFSSQSPQAQGPTNGQKSVVLRDPLLSALTGLFTIFTFLAGRDGEISQQTHFILQFLRLMVQCGKDRTRIVLQGMPQTLVPCLLKALPELFTTDILLRFYDIQTAVGRKATARDLCMLRNINLKPSK
Length999
PositionTail
OrganismMelipona quadrifasciata
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Apoidea> Apidae> Melipona.
Aromaticity0.07
Grand average of hydropathy-0.041
Instability index52.47
Isoelectric point6.45
Molecular weight112155.97
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05011
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     126.06|      57|     197|     107|     238|       1
---------------------------------------------------------------------------
  107-  134 (28.71/131.89)	...............CILSLLEFLESIQVGITCRGKPEEDLLA.........................................................................
  191-  207 ( 9.95/ 9.72)	...........................................aavlsivhwllqcylhtltkmpqnspltpqptelmdkpasilkqmlnsdflcammyLAKYDDKDLYIEVVKKC
  224-  301 (25.92/14.45)	PIEESLKKLCnleVD......................................cltlspemsqmesithclqplfavqvlqnpstetsvfvnqmlmvqrLKNYTNARLYCEIIRAC
  809-  848 (61.48/ 0.00)	PQSSVLAKLC...VYCIFSTLEHNNSNPSRGNSRKRVRRDLDA.........................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.32|      34|      85|      53|     102|       4
---------------------------------------------------------------------------
   53-   86 (58.13/46.40)	VYNLADCIL.......QQALVGLGPNQLV...LSYLKHSLSSQL
  141-  184 (51.19/18.30)	VHWLLQCYLhtltkmpQNSPLTPQPTELMdkpASILKQMLNSDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.19|      16|      17|     920|     935|      13
---------------------------------------------------------------------------
  920-  935 (29.60/20.65)	QQTHFILQFL.RLMVQC
  938-  954 (24.59/15.82)	DRTRIVLQGMpQTLVPC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05011 with Med24 domain of Kingdom Metazoa
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