<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05008

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceVIDMGAVVDVITALEKTTITKEVLEITRLGKYINELRRKTNNDALAKRAKDLVRRWRDMVLPSAHSTPQPTPADTAPPALNGAKPHSPALRCFKPQSPALRGLMPPQNPLLRDTNPLRVLSPVLSVHSDHSHSPNASSNKQSITVTSNHRTSSDVPPTLGSSSQHHSMEAVPRTHSSNKRLRKDDLKDQHNYQHHDSDSITESESFIKKQRLNGENISGNLNMQVPSPTFKERISDQFTESSTDPDESGPKKRGRKKGSKSMKKQPVLEDRVKEKLASISRNPKLKTTQELLADLRARGTNSSINSSAQPSQSVESSSMEDILRNSNEQVSKFLRGPQNNLSHRNTVSEASPESRLKPTENCHDVPSKCEESGVVYKEKSVTNVQNNQPEQCQDLTVEEILAKLPPIDPSSIDWSECETEPTEDQNTEYPPRQVTAEDIERLHVQCVEGLNGNFQPKLSSLTSTSNEKQEEPSEINGVNNVHSRPDEEFREWHQMLARPSCNGQILHILPYVIID
Length515
PositionUnknown
OrganismMelipona quadrifasciata
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Apoidea> Apidae> Melipona.
Aromaticity0.03
Grand average of hydropathy-0.916
Instability index61.80
Isoelectric point6.70
Molecular weight57523.41
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP05008
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.94|      19|      23|      78|     100|       1
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   82-  100 (37.90/25.12)	G.AKPHSPALRCFKP...QSPAL
  102-  124 (28.04/ 8.91)	GlMPPQNPLLRDTNPlrvLSPVL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.13|      15|      23|     324|     343|       2
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  324-  343 (11.31/27.36)	RN.....SNEqvSKfLRgPQNNlSH
  344-  363 (24.83/14.72)	RNtvseaSPE..SR.LK.PTEN.CH
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.55|      19|      23|     388|     406|       3
---------------------------------------------------------------------------
  388-  406 (33.41/17.65)	QP.....EQCQDLTVEEILAKLPP
  408-  431 (30.14/15.30)	DPssidwSECETEPTEDQNTEYPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.66|      23|      23|     257|     279|       6
---------------------------------------------------------------------------
  219-  241 (24.15/11.22)	.GNLNMQvPSPTFKE.RISDQFTES
  257-  279 (35.01/19.26)	KGSKSMK.KQPVLED.RVKEKLASI
  281-  304 (27.50/13.70)	RNPKLKT.TQELLADlRARGTNSSI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.10|      19|      26|     164|     182|       7
---------------------------------------------------------------------------
  164-  182 (34.98/19.03)	QHHSMEAVPRTHSSNKRLR
  193-  211 (31.12/16.18)	QHHDSDSITESESFIKKQR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP05008 with Med26 domain of Kingdom Metazoa

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