<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP05004

Description Dorsal root ganglia homeobox protein (Fragment)
SequenceGRSWIPRGARRTVQGYGGRWTVIREGAEEIGKVLGPGLGCRPLPRVTDRLFYAVHGVVTSSRRYVRISKVLSYPTPFYFGVQQLRAGNATKATTFVEPCRRNASRLTPGHLLRNNQEACSLEITGHDNGETRLSLQLQIGSVHTHQPNNNHHHHTHHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSQSQVPGAGGGGGPGGGTVARPGGMFCYHCPPGLPTPRLPPTLEYPFAATHPYTSYSAYHPALHGVGEDSFVRRKQRRNRTTFTLQQLEELESAFAQTHYPDVFTREDLAMKINLTEARVQGAIGKQQHTRGMSESTKRRRTAGYNKVYFSWYYVKLGSLVELELFKKHSAAVVAVGSLNMHAGKRPNVWFQNRRAKWRKSERLKEEQRKREGNGGAGALETTGLAPPTSSSAGPSPTGHDPEGTTSSSAPDAEDAGPDGAGGSRSPSTTSASVSPRPQQSQPSLGGVSTPPPTPIRAPPPPSSTVGGLGPPGESGSAASRAAGVYALLRSFLPSSQLKKTERPVPCAVDVSRGIGADSATAEGAPGLAAGFRPVEPPTSLFFSPHLAAQFSPPLFGNKVVSSAPTSLTSTTPSLWTSSDHRPGSLQDMLSWSPAGWPGSLCGCCKPGTGDLHRNSSLAELRRKAQEHSTASALLGGLAGFPGGLPLPLPLPLLPPLLGLSRRPEHHHHHLPSMVHQIQPTTKEDP
Length716
PositionTail
OrganismMelipona quadrifasciata
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Apoidea> Apidae> Melipona.
Aromaticity0.06
Grand average of hydropathy-0.678
Instability index69.00
Isoelectric point9.93
Molecular weight77181.39
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP05004
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.11|      15|      15|     158|     172|       1
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  158-  172 (32.55/15.88)	QQQQQQQQQQQQQQQ
  174-  188 (32.55/15.88)	QQQQQQQQQQQQQQQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.11|      17|      18|     466|     482|       2
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  209-  227 (25.71/ 8.49)	VARPGGMFCYHCPPglPTP
  469-  485 (32.40/13.04)	QQSQPSLGGVSTPP..PTP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     504.98|     141|     186|     312|     459|       3
---------------------------------------------------------------------------
    1-  110 (120.89/44.63)	...GRSWIPRG.....ARRTVQG.YG..G...RWTVIR.....EG..........AEEIG..KVLGPGL..GCRPlprvtdrlfyavhGVVTSSRR.YVRISKVLSYPtpfyfgvQQLRAGN....ATKATTFVEPCR.....................RNASRLTPGH......................................
  312-  459 (239.42/106.69)	GAIGKQQHTRGMSESTKRRRTAG.YN..KVYFSWYYVK.....LGSLVELEL.FKKHSAAvvAVGSLNMHAGKRP.............NVWFQNRRaKWRKSERLKEE.......QRKREGNggagALETTGLAPPTS.....................SSAGPSPTGHDPEGTTSS.....SAPDAEDAGPDGAGGS....RSPST
  497-  639 (144.68/54.74)	GGLGPP....GESGSAA.SRAAGvYAllRSFLPSSQLKkterpVPCAVDVSRgIGADSAT..AEGAPGLAAGFRP.........................................................VEPPTSlffsphlaaqfspplfgnkvvSSAPTSLTSTTPSLWTSSdhrpgSLQDMLSWSPAGWPGSlcgcCKPGT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.75|      32|     543|     123|     154|       4
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  123-  154 (59.66/31.68)	ITGHDNG.ETRLSLQLQIGSVHTHQPNNNHHHH
  668-  700 (57.09/29.98)	LAGFPGGlPLPLPLPLLPPLLGLSRRPEHHHHH
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.83|      18|      23|     258|     278|       7
---------------------------------------------------------------------------
  258-  278 (25.72/22.85)	EDSFVrrkQRRNRTTFTLQQL
  282-  299 (32.11/19.45)	ESAFA...QTHYPDVFTREDL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP05004 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ETRLSLQLQIGSVHTHQPNNNHHHHTHHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSQSQVPGAGGGGGPGGGTVARPGGMFCYHCPPGLPTPRLPPTLEYPFAATH
2) GKRPNVWFQNRRAKWRKSERLKEEQRKREGNGGAGALETTGLAPPTSSSAGPSPTGHDPEGTTSSSAPDAEDAGPDGAGGSRSPSTTSASVSPRPQQSQPSLGGVSTPPPTPIRAPPPPSSTVGGLGPPGESGSAASR
3) KKTERPVPCAVDVSRGIGADSATAEGAPGLAAG
4) PLLGLSRRPEHHHHHLPSMVHQIQPTTKEDP
5) TKATTFVEPCRRNASRLTPGHLLRNNQEACSLEITGHD
130
374
529
686
90
241
511
561
716
127










Molecular Recognition Features






MoRF SequenceStartStop




NANANA