<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04938

Description Hpo
SequenceMSSNTNSHGELKKLSEESLLQPPEKVFDIMYKLGEGSYGSVFKALHKESSSIVAIKLVPVESDLHEIIKEISIMQQCDSPYVVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLKGLVYLHLRRKIHRDIKAANILLNTEGFAKLADFGVAGQLTDTMAKRNTVIGTPYWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGDIHPMRAIFMIPQKPPPSFREPDRWSTEFIDFVSKCLVKDPNERATATDLLDHEFIRNAKHRSILKPMLEETCAIREHQRANRAADMALNQAKLLATQDPSLMLQEEETDFNAGTDKTFFEDPGTLVPEKFNEYQQTSASDATMIAHPEQEIDEGTLGPGGLRPNMAKAAAKAAAVPADVAAVDSGTMVELESNLGTMVINSDSDDSTTAKRSEDQKPRNRYRPQFLDHFERKNASETRADDKSVSTPTEYSPAAAEQQLLQQQQQQQQQQQQQAQLLEQPQHDANWEQNMELHFQQISAINQYGLQQHQLQQQQQQQQQQQQPHLLVSHALMNEQLVALNNQQNLLRNNATPQQQQQQQQQQPSAPPAYQHQHLHTQSHPFVEGEFEFLKFLTFDDLNQRLSNIDHEMELEIEQLNKKYNAKRQPIVDAMNAKRKRQQNINNNLIKI
Length670
PositionKinase
OrganismDrosophila busckii (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.07
Grand average of hydropathy-0.691
Instability index54.82
Isoelectric point5.34
Molecular weight76292.85
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine kinase activity	GO:0106310	IEA:UniProtKB-EC
protein threonine kinase activity	GO:0106311	IEA:UniProtKB-EC

GO - Biological Process
signal transduction	GO:0007165	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04938
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     133.58|      32|      38|     515|     546|       1
---------------------------------------------------------------------------
  467-  519 (43.75/15.28)	VSTPTEYSpaaAEQQLLQQ....QQQQQQQQQQQaqlleqpqhdanweqnmeLHFQQ
  520-  558 (54.89/20.62)	ISAINQYG...LQQHQLQQ....QQQQQQQQQQP...........hllvshaLMNEQ
  559-  600 (34.94/11.05)	LVALNN......QQNLLRNnatpQQQQQQQQQQP........sappayqhqhLHTQ.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.20|      29|      34|     346|     379|       4
---------------------------------------------------------------------------
  346-  379 (43.45/37.66)	GTLVPEKFNEYQQTSASDATMIAhpeqeIDEGTL
  382-  410 (46.75/27.73)	GGLRPNMAKAAAKAAAVPADVAA.....VDSGTM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.69|      12|      17|     266|     280|       5
---------------------------------------------------------------------------
  266-  277 (19.92/ 6.35)	RATATDLLDHEF
  284-  295 (19.77/11.24)	RSILKPMLEETC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.85|      16|      17|      72|      87|       7
---------------------------------------------------------------------------
   72-   87 (31.58/20.96)	SIMQQCDSPYVVRYYG
   88-  103 (34.27/23.30)	SYFKQYDLWICMEYCG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04938 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALNNQQNLLRNNATPQQQQQQQQQQPSAPPAYQHQHLHTQ
2) DPGTLVPEKFNEYQQTSASDATMIAHPEQEIDEGTLGPGGLRPNMAKAAAKAAAVPADVAAVDSGTMVELESNLGTMVINSDSDDSTTAKRSEDQKPRNRYRPQFLDHFERKNASETRADDKSVSTPTEYSPAAAEQQLLQQQQQQQQQQQQQAQLLEQPQHDANWEQNMELH
561
344
600
516










Molecular Recognition Features






MoRF SequenceStartStop




NANANA