<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04931

Description Flt3-interacting zinc finger protein 1 (inferred by orthology to a human protein)
SequenceMSSQPQNIVSPFPQPPEYAKQYTDENIAKKVVLPPPPVPTEFTVFGEEYNFEEEMIRSLRTQEMQQLFSSNGDWRSELKKLNRSTVAAFLDLLDILIRSNTIYANIYLRGQFQDVIERFRFHLSAGRQALNQCIDEIVLPDEVPELDGSDGEEDAKKNRLEMMDGNGVDAAELDRCARHSMAERRRAFRKDIALCRFFDANKLSSSSPLGLSPNPDHPSTAIATQSGVLSSQQQQLIQSTSARAPHPLRRAFMCTECHKSFRLREELYVHAEMCFLEAFENEAVSVFSDMPSLDNPATSVGPIPSGITVKGDPQQPPKLDAIRSAHLVMLPSQSTTSAANIDYCYDDIDDIDNVNDEQIEFGEEPMNKLRRFDVDASCSIEDIRQPISYSTESETPAEMLNARTIEGSGGLKLVVSVEKCDSGSGGMGMGDESEDSADEQYTDFDDDQHPLPIGSRGTALMGSNGGMTSGVGIMNGSGKVIGALANAEDDTFRPKMECPTCGLVLYRHNFSTHYRIHTGEMPFSCHFCLKRFRTTSALKVHIRAHTGEKPYSCPKCSYACITKRNLDRHIINNHVREGERRGPRQRKSRYRNESDDEYFGIQDIVDEMEVDNPDHHYVVITENDVSLEAAEEPIETMEPIETELEEVNSTQETSTA
Length656
PositionMiddle
OrganismAnisakis simplex (Herring worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Ascaridomorpha> Ascaridoidea> Anisakidae> Anisakis> Anisakis simplex complex.
Aromaticity0.07
Grand average of hydropathy-0.595
Instability index63.89
Isoelectric point4.82
Molecular weight73459.08
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP04931
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.73|      16|      25|     513|     528|       1
---------------------------------------------------------------------------
  513-  528 (37.76/19.56)	HYRIHTGEMPFSCHFC
  541-  556 (35.97/18.36)	HIRAHTGEKPYSCPKC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.06|      50|      58|     287|     338|       3
---------------------------------------------------------------------------
  287-  338 (81.05/55.20)	FSDMPSLDN...PATSVGPIPSGITVKGDPQQPPKLDAIRSAhlVMLPSQSTTSA
  345-  397 (81.01/49.03)	YDDIDDIDNvndEQIEFGEEPMNKLRRFDVDASCSIEDIRQP..ISYSTESETPA
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP04931 with Med7 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) HHYVVITENDVSLEAAEEPIETMEPIETELEEVNSTQETSTA
2) SPLGLSPNPDHPSTAIATQSGVLSSQQQQLIQSTSA
615
207
656
242

Molecular Recognition Features

MoRF SequenceStartStop
1) EYAKQYTDENIAK
17
29