<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04921

Description Uncharacterized protein
SequenceMKSLSVVSWHHQTPERRPLKRSRLGPPDVYPQDTRQEEDNLGADRLKKGYQVAVTSYEHESIVWNVKVPRFDRPPEEAMTRGAQIVMQILNKKLELNANLDKERKRATKDGVFQNFSHTVRQADKSKERKEWFTDLAIGKSLAVLAKRPPFFRKKEDALEYLCDFKVPIQRALWFLKLIAIGQGIATNVNKQKKSTNDQLASEHASLFTKYIKVMLSQMSDSAKLDTNIVYTERWPHFVCICKHAYEDGMIERQEFLMDLCDIFADRFLQRSDKPHFLTLFRLFLTFFSQYTDQITQNLLLSRRCAFLVAKRLALNKKEMEDGVGRVVDMNEMFDEMIQCQNQRSIILILCGMLYAILIDCPGALIWNNFQVAEGRPPPLLHNLCGSPLDVLPCSIECLPIPQGHGNDKLSELIQLRVVEVKRRSRAVDNHWSINHSHKAGFALIVQTCLEILGALDAARLDQPRAIEKIYNQIFNNSYREKFDHEDAIRVKVLIHWAVTVEREGTYRALVVASVLALRVNHRKGFKFGERHLQDILLEYLDTEGPKFGDEYFHEEFANLMHLFMELQRAGVFSHDSYVKGLITTGEMSEQLPIMTLIKNRIQQSVSVLNQRNVNADNMFSGMNNDEKRFLMSSSTNLLVNMPLEADDEHPFMGYEVTSHERFLIHLSVPQTNEYRSECNQRALLLYGIGEQRDVIKNELKKVAREIAKIWTKRIVIEFSFSKPSEIRFKKRASRDQINEALQKFKSQTYYDQLVLCGWCCDNFILMITDFVDGHSAVLPAAEGFDVLLNMMEHCKNIYGIMELAEELLPLLASVEQVLSERRVDCVPSIVSTHLGYILCSYISHNYYYFIHSENAPEIVNGLYNLIENQLKSTESCLTGWGRSIGIFVLNAKQQLIECDLISNKLVDAKRDLLKRLLPSIQQTKFSTSITSAKYNAHLFKEFLDEPKRMFSFNDYRRINALINDEEARYSFVISALNAARQCGNDYDKLVELSNICSHLSSQANICNEWCGALQALCCSSVAGSNHGFADLFLVINVEDSKCHYSIATFYMLLASRNCFSMNALFYQLLQSVFSSLLKSDSSKTDVDAEAGVCLALLVIADMVCQNDEPIILSSLYTGEKEPRKHLSGMADKWALSEGHLHDIGESMFELLLTISIIADYTKNKLRDRIEDKGEHNFRREYISQISKGVLMAMCEQDWVTQRIYRVCEQTNMDVFNSHRLKKNCLGQQLLRMALRRKCERLIVQELTVCNGNSKKSLIDKLLSVLNIWNIRATYFDLKLMIKEISPEGSSSKHAQQGAIAADALIAEIGRCCRDLFTSKIDKKLTDAAIGKAFRLKHITNYWLISPLIRLCPKPGNLPASFPAVTVQAKFLKEAASMLDTATDCSRERIQQSAWLLSEEPFLNLVLTCLKGEDQQRDCLVGSLLKQLQDLVAKTKDNATLPYLRKFATEREGLLLRLSLIGGMFDSVCQQNSCDAWALLLFQLMLFGIVSRERDRFLFESCFDMLSTLLVWSITDPMNAVPVNSQDPDTKYRFTNYCVIVKKLRVSFKNRFIISLYSAILTVFNNHFVFLSFDCVMKVSLVIVIGNELKKELNERALIPELRCLMQFLPIPKPAFELITCEPYGTLPISPQKLSKGQIGSSPVKANKQGLQFAEKIKISSYDMVQNFNSESSLKRTWTWTMFQAVKLDRCPVAVQKHIQRLIQHAHYNEFVRPTICGMDRPPNLDIYLSPPTMDVSETPVSSVHHVSSNSTPATTTSTSVTAAQMSVPSQAPSNEPMIFAGQVGAVQQLPDMGRVQATASPRGSRGGRRKNAGGLSTRSQGTTRKKKTAEQLAAVVGAVSSNATASSQAVLTGTAPAVTAAASIAGGPGQGQAPAQAYGWGSVGPPGQAPPPSAQPPGGVNQATQSQLMHGAPPQQFPSNQQALEDSKTKIHTMILKRQAQAASGNTASQNFQGMASVSANQNQYGAMMMKMDGSSMRVDQQQSYPAGAPPQLSMTQDQNAQFGAQQRNYTAQQSQPNANSVFDSRMMSHHQAAAAAAAAAQQQAMQFQQQYQQQQY
Length2058
PositionKinase
OrganismAnisakis simplex (Herring worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Ascaridomorpha> Ascaridoidea> Anisakidae> Anisakis> Anisakis simplex complex.
Aromaticity0.08
Grand average of hydropathy-0.246
Instability index42.61
Isoelectric point8.52
Molecular weight232029.08
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04921
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.81|      16|      41|     128|     143|       1
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  128-  143 (29.52/21.08)	ERKEWFTDL.AIGKSLA
  170-  186 (25.30/16.85)	QRALWFLKLiAIGQGIA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     398.15|     105|     123|    1769|    1889|       2
---------------------------------------------------------------------------
 1744- 1836 (135.68/83.10)	VHHVSSNSTPA.......TTTSTSVTAA.........Q...MSVPSQ..............aPSNEPmifAGQVG.AVQ.QLPDMGRV........QATASPRGSRGGRRKNAGGLSTRSQGTTRKKKTAEQLAAV
 1837- 1955 (162.97/103.91)	VGAVSSNATASSQAV..LTGTAPAVTAAASI.AGGPGQ...GQAPAQAYGwgsvgppgqappPSAQP...PGGVNqATQsQLMHGAPP........QQFPSNQQALEDSKTKIHTMILKRQAQAASGNTASQNFQG
 1956- 2044 (99.50/51.45)	MASVSANQNQYGAMMmkMDGSSMRVDQQQSYpAGAPPQlsmTQDQNAQFG......................................aqqrnytaQQSQPNANSVFDSR.....MMSHHQAAAAAAAAAQQ....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     324.09|      93|     123|     892|    1014|       3
---------------------------------------------------------------------------
  828-  891 (66.88/80.88)	.......PSIVSTHLGYILCS.......YISH....NYYYF......IHSENAPEIVNGLYNLIENQLKSTESCLTGwGRS.IGifvlN.......................................
  912- 1014 (136.45/123.65)	DLLkrLLPSIQQTKFSTSITS.....AKYNAH....LFKEFLdepKRMFSFNDYRRINALINDEEARYSFVISALNA.ARQ.CG....NDyDKLVeLSNICS.......HLSSQAnicNEWC...GAL
 1031- 1141 (120.77/76.23)	DLF..LVINVEDSKCHYSIATfymllASRNCFsmnaLFYQLL...QSVFS..SLLKSDSSKTDVDAEAGVCLALLVI.ADMvCQ....ND.EPII.LSSLYTgekeprkHLSGMA...DKWAlseGHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.53|      14|      31|     339|     352|       6
---------------------------------------------------------------------------
  339-  352 (26.96/15.79)	QCQNQRSIILI..LCG
  371-  386 (22.57/11.96)	QVAEGRPPPLLhnLCG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.08|      14|      36|     230|     243|      11
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  230-  243 (30.06/17.64)	VYTERW......PHFVCICK
  263-  282 (20.02/ 9.28)	IFADRFlqrsdkPHFLTLFR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.02|      16|      35|     620|     635|      12
---------------------------------------------------------------------------
  620-  635 (29.27/19.79)	FSGMN.NDEKRFLMSSS
  652-  668 (25.75/16.46)	FMGYEvTSHERFLIHLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.61|      24|      81|     419|     442|      13
---------------------------------------------------------------------------
  419-  442 (41.78/31.46)	VEVKR....RSRAVDNHWS..INHSHKAGF
  456-  483 (27.86/18.04)	LDAAR..ldQPRAIEKIYNqiFNNSYREKF
  499-  526 (28.97/19.10)	VTVERegtyRALVVASVLA..LRVNHRKGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.69|      31|      37|    1404|    1434|      14
---------------------------------------------------------------------------
 1404- 1434 (49.62/34.97)	NLVLTCLKGEDQQRDCLV..GSLLKQLQDLVAK
 1438- 1470 (45.07/30.98)	NATLPYLRKFATEREGLLlrLSLIGGMFDSVCQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.60|      21|      41|    1293|    1313|      15
---------------------------------------------------------------------------
 1293- 1313 (35.76/26.96)	KHAQQGAIAADALIAEIGRCC
 1314- 1334 (28.51/19.67)	RDLFTSKIDKKLTDAAIGKAF
 1337- 1352 (27.33/18.48)	KH.....ITNYWLISPLIRLC
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04921 with Med12 domain of Kingdom Metazoa
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