<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04907

Description Uncharacterized protein
SequenceMIDYQFKEELVKTRERVEDLYSFEGSKVGRGTYGHVYKAQPRHPEQIAKNGAKEFALKLIEGQGFSMSACREIALLRELKHPNLIKLQRVFLTSERKVWLLFDYAEHDLWHIIKFHRAAKQKKQPVLVPKGMVKSLLYQILDGIHYLHSNWILHRDLKPANILVMGEGPGVERGRVKIADMGFARIFHNPLKPLAELDPVVVTFWYRAPELLLGAKHYTKVCYANCTLQRYMDKHKIKADTRSFSLLQRLLTMDPIKRVTAQDAMDDHYFKEDPRPTADVFSGCDIPYPKREFLSDENDDKSASASKTQQAPPPQQSQQQAIGVHPQQPIMEPAAKKMRMQQSQQMPPTQPQMETIVNAPTGGMFTGGGGGEYPAVGSGTSMNTKASVAFEQQPHGPMMQPQHMNPQLQQMQYTQHQQHIIGQQPNVYQQSQMGMGQQMSGAAQTQMAPRPMQMSTQQSMIPSSYQQQMMQPGMGQQMMSASGQSMMGEQPMAGPHPQMAPQASMMQPMRPQMQYMDQNGRLMQQTSGMMVPQPGQEMMPPQQGQYIMQQQQQWGPMQPRYQ
Length562
PositionKinase
OrganismAscaris lumbricoides (Giant roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Spirurina> Ascaridomorpha> Ascaridoidea> Ascarididae> Ascaris.
Aromaticity0.07
Grand average of hydropathy-0.685
Instability index54.02
Isoelectric point9.22
Molecular weight63946.06
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP04907
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     158.29|      32|      33|     447|     478|       1
---------------------------------------------------------------------------
  404-  439 (46.91/10.91)	MNPQLQQMqytQHQQHIIgqqPNVYQQSQM..GMGQQM
  447-  478 (68.70/18.87)	MAPRPMQM...STQQSMI...PSSYQQQMMQPGMGQQM
  493-  515 (42.68/ 9.37)	AGPHP.QM...APQASMM.........QPMRPQM..QY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.22|      14|      16|     254|     269|       2
---------------------------------------------------------------------------
  254-  269 (23.33/18.98)	DPikRVTAQ..DAMDDHY
  273-  288 (21.89/11.18)	DP..RPTADvfSGCDIPY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.65|      22|      33|     297|     326|       3
---------------------------------------------------------------------------
  297-  319 (33.42/11.40)	ENDDKSASASKTQQAPPPQqSQQ
  332-  353 (44.24/21.89)	EPAAKKMRMQQSQQMPPTQ.PQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.17|      34|      71|     105|     146|       6
---------------------------------------------------------------------------
  105-  146 (51.23/48.74)	AEHDLWHIikFHRAAK..QKKQPVLVpkgmvkSLLYQ....ILDGIHY
  179-  218 (52.94/31.22)	ADMGFARI..FHNPLKplAELDPVVV......TFWYRapelLLGAKHY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.89|      11|     139|     393|     403|       7
---------------------------------------------------------------------------
  393-  403 (26.62/11.32)	QPHGPMMQPQH
  533-  543 (23.26/ 8.83)	QPGQEMMPPQQ
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP04907 with CDK8 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) REFLSDENDDKSASASKTQQAPPPQQSQQQAIGVHPQQPIMEPAAKKMRMQQSQQMPPTQPQMETIVNAPTGGMFTGGGGGEYPAVGSGTSMNTKASVAFEQQPHGPMMQPQHMNPQLQQMQYTQHQQHIIGQQPNVYQQSQMGMGQQMSGAAQTQMAPRPMQMSTQQSMIPSSYQQQMMQPGMGQQMMSASGQSMMGEQPMAGPHPQMAPQASMMQPMRPQMQYMDQNGRLMQQTSGMMVPQPGQEMMPPQQGQYIMQQQQQWG
291
555

Molecular Recognition Features

MoRF SequenceStartStop
NANANA