<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04807

Description Uncharacterized protein
SequenceMQFSPIEIKERLTRALDEDNNVSDIPAVLEVIATLESYPITREALEQTRLGKLVNELRKKTTNDDLARRAKRLVRSWQKLISPPTDGTTVNGERINTNSPSPGMTVLTGSAGSMPVSPASLRFSPGLVKSSPCGIAVSSKNNSPCLRVNATPGTPRLHPTSLKVDPNGIQRSNISPKSVCPLRGVAPLTSTPKGPISPKTMCPRRAGLPSSLTPKQHSPSIPLSSTPKGNCPNGPFKNSASSDGRCENNLMSNQTYSPTRSTERNCMSKEKNSLSKVGSLHPGKCSPIINHSRDRINAGTLNDQKPTPKGKLSNRKRTCNDSGGAPPAKRSVPADKYVKDLHSKEKTVNGISRNVCQNLETLEKKKSGNVLPKSKSVMDNLFTYMSGDSNDSFKSSTSKRNLTFHAKQDKTKTSKVKTTAQLIAELRAKSGSTGSQLRGDIIDKLKRQPSPNSLDVRLKSGKHKARPMLSQTKTELVERFLKNSIRPNLKDESEYLELDPCRLLECDLPNGQTPMERSLGSSSSTAQEVSSNSNHLSLLEIYNSLPPLNLDKIDWDDDKYEVTEHTEPITDSNIDRLHNEYWSGVNGQWDSTGSWRDWTHTMSVESFEGSKLDLLPYVNID
Length621
PositionUnknown
OrganismOctopus bimaculoides (California two-spotted octopus)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Cephalopoda> Coleoidea> Octopodiformes> Octopoda> Incirrata> Octopodidae> Octopus.
Aromaticity0.04
Grand average of hydropathy-0.776
Instability index48.64
Isoelectric point9.50
Molecular weight68215.23
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04807
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.13|      19|      19|     174|     192|       1
---------------------------------------------------------------------------
  153-  189 (25.47/11.35)	GTPrlhptslkvdpngiqrsnISPKSVCPLRGVAPLT
  190-  211 (28.66/13.81)	STP...............kgpISPKTMCPRRAGLPSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.68|      14|      17|     300|     313|       2
---------------------------------------------------------------------------
  300-  313 (24.94/13.90)	TLNDQKPTPKGKLS
  318-  331 (24.74/13.73)	TCNDSGGAPPAKRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.18|      31|      33|     425|     455|       4
---------------------------------------------------------------------------
  425-  455 (51.15/26.88)	ELRAKSGSTGSQLRGDIIDK.LKRQPSPNSLD
  460-  491 (47.03/24.21)	SGKHKARPMLSQTKTELVERfLKNSIRPNLKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.13|      17|      33|     122|     138|       5
---------------------------------------------------------------------------
  122-  138 (31.51/16.22)	RFSPGLVKSSPCGIAVS
  156-  172 (29.61/14.84)	RLHPTSLKVDPNGIQRS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.95|      15|      33|     225|     239|       7
---------------------------------------------------------------------------
  225-  239 (31.28/15.97)	STPKGNCPNGPFKNS
  261-  273 (23.63/10.33)	STER.NCMSKE.KNS
  279-  290 (18.04/ 6.21)	SLHPGKC..SPIIN.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.58|      19|      19|     341|     359|       8
---------------------------------------------------------------------------
  341-  359 (32.93/22.24)	LHSKEK.TVNGISRNVCQNL
  362-  381 (26.65/16.51)	LEKKKSgNVLPKSKSVMDNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.01|      31|      72|     518|     551|       9
---------------------------------------------------------------------------
  518-  551 (46.36/34.26)	SLGSSSSTAQEVSSNSNHLSLLEIynsLPPLNLD
  591-  621 (56.65/33.75)	STGSWRDWTHTMSVESFEGSKLDL...LPYVNID
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04807 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSQLRGDIIDKLKRQPSPNSLDVRLKSGKHKARPMLSQTK
2) NNSPCLRVNATPGTPRLHPTSLKVDPNGIQRSNISPKSVCPLRGVAPLTSTPKGPISPKTMCPRRAGLPSSLTPKQHSPSIPLSSTPKGNCPNGPFKNSASSDGRCENNLMSNQTYSPTRSTERNCMSKEKNSLSKVGSLHPGKCSPIINHSRDRINAGTLNDQKPTPKGKLSNRKRTCNDSGGAPPAKRSVPADKYVKDLHSKEKTVNGISRNVCQNLETLEKKKSGNVLPKSKSVMDNLFT
3) SFKSSTSKRNLTFHAKQDKTKTSKVKTTAQLIAELRAK
4) WQKLISPPTDGTTVNGERINTNSPSPGMTVLTGSAGSMPVSPASLRF
434
141
392
77
473
383
429
123










Molecular Recognition Features






MoRF SequenceStartStop




1) QLRGDIIDKLK
436
446