<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04805

Description Uncharacterized protein
SequenceMSKHLGVSSFPLPPMQYVRYCTDENMAKGIPAPPPTQEDYTVFGVPSNINDPIQTLESQGLTQLYPENCNRKKEMKKLNHSILVCFLDLIDILIQNPSSSDRNEKLNDLRLLFINLNHLINEIRPNQAREALRMMMMKQKCQTVELLNDLEKKLAEAKELIAKSIQNLQVSNPDDCEAFKLSGLLESGSCRLNENIEMTSECSVQDYTINTIEYLNEVCNFGREDSVIQSEVKMENIDCKSKVLAAQESNRDLGATGGKACFDSKLSVRNTADVKIENEDILTNTCANKNQKDMEFTDSMKVTADYIGLSNSLLAAKNGVQLALCEVKAMSEDLDLSECKQGVINNTNKTCIDVIENEECNVKLERKSKDSCSEDIGSSQSESVDVCFSQSKQDEDAQSKQEAERDSTHETGDDLPLLQGAENEVSLIHVKQGWERDASLERQAKDDASLVQSVGGDVSLMKSEQGGESNLQSKQGDVLFRQNKKEAEGDSRLVSPNRNLEDDTQFLLYKQGSEREMLLQETSDNLVAMESRKLLARDTNIEESKEEIYDKNIGENKEIYDDKNIGENKEIYDKNIGENKEIYDDKNIGENKETYDKNIGENKEIYDDKNIGENKEEIYDINIRESKEEIYEDTNVRKSKGEITDDTNMGESKGRDFGTNAKESKEDIHDDTNIWETKEVTNIDEGVVESKEEMPCGKILMTNQEETTGDMSATKNQEETANDSNVVESQEETACVTNEVESQEEADCDANEVENQETAYNINAESQKEMDSSVRGLESQDERGDGRGITESKKEWEGNINVAGSQEEMAGNARIMESQVPSKSNKTTDDDPDNVSTLQGKRKHDDDVGHEEMKKKLEDNFSN
Length863
PositionMiddle
OrganismOctopus bimaculoides (California two-spotted octopus)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Cephalopoda> Coleoidea> Octopodiformes> Octopoda> Incirrata> Octopodidae> Octopus.
Aromaticity0.04
Grand average of hydropathy-0.942
Instability index56.99
Isoelectric point4.47
Molecular weight97054.67
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04805
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     247.26|      22|      22|     547|     568|       1
---------------------------------------------------------------------------
  516-  544 (21.19/ 6.72)	EMLLQETSDNlvamesrK.L.LARDTNIEES
  547-  568 (47.04/23.16)	EIYDKNIGEN.......K.E.IYDDKNIGEN
  570-  591 (47.04/23.16)	EIYDKNIGEN.......K.E.IYDDKNIGEN
  593-  614 (46.29/22.68)	ETYDKNIGEN.......K.E.IYDDKNIGEN
  617-  639 (32.72/14.06)	EIYDINIRES.......KeE.IYEDTNVRKS
  642-  652 (21.52/ 6.93)	E....................ITDDTNMGES
  655-  677 (31.46/13.26)	RDFGTNAKES.......K.EdIHDDTNIWET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.86|      23|      24|     765|     787|       2
---------------------------------------------------------------------------
  741-  763 (36.29/16.94)	ESQEEADCDANEVENQET.AYNIN
  765-  787 (37.12/17.48)	ESQKEMDSSVRGLESQDE.RGDGR
  791-  814 (32.45/14.43)	ESKKEWEGNINVAGSQEEmAGNAR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     195.23|      40|      40|     412|     451|       3
---------------------------------------------------------------------------
  332-  375 (42.81/16.25)	.EDLDLsecKQGVINNTnkTCIDVIENEECNVKLERK....SKDSCSED
  383-  410 (35.02/12.26)	SVDVCF...SQSKQDED..A..QSKQEAERDSTHE..............
  412-  451 (66.78/28.56)	GDDLPL...LQGAENEV..SLIHVKQGWERDASLERQ....AKDDASLV
  455-  494 (50.62/20.27)	GGDVSL...MKSEQGGE..SNLQSKQG...DV.LFRQnkkeAEGDSRLV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.05|      25|      25|     130|     154|       4
---------------------------------------------------------------------------
  107-  127 (30.41/18.72)	NDLRLLFINLN....HLIN..EIRP.NQ
  130-  154 (40.78/27.68)	EALRMMMMKQKCQTVELLN..DLEK.KL
  156-  181 (24.86/13.92)	EAKE..LIAKSIQNLQVSNpdDCEAfKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.97|      19|      38|     678|     696|       5
---------------------------------------------------------------------------
  678-  696 (33.62/20.00)	KEVTNIDEGVVESKEEMPC
  704-  721 (25.19/13.07)	QEETTGDMSATKNQEETA.
  723-  735 (18.16/ 7.29)	......DSNVVESQEETAC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      82.19|      25|      58|     234|     258|       6
---------------------------------------------------------------------------
  249-  273 (38.40/25.06)	SNRDLGATGG........KACFDSKLSVRN..TAD
  277-  309 (23.20/12.07)	ENEDI.LTNTcanknqkdMEFTD.SMKVTAdyIGL
  310-  328 (20.59/ 9.83)	SNSLLAAKNG........VQLALCEVK........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.19|      20|      22|      11|      30|       7
---------------------------------------------------------------------------
   11-   30 (39.62/28.41)	PLPPM...QYVRYCTDENMAKGI
   31-   53 (33.57/22.95)	PAPPPtqeDYTVFGVPSNINDPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.28|      13|      22|     192|     204|       8
---------------------------------------------------------------------------
  192-  204 (22.57/13.53)	LNENIEMTSECSV
  215-  227 (21.71/12.69)	LNEVCNFGREDSV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04805 with Med7 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) CFSQSKQDEDAQSKQEAERDSTHETGDDLPLLQGAE
2) RDASLERQAKDDASLVQSVGGDVSLMKSEQGGESNLQSKQGDVLFRQNKKEAEGDSRLVSPNRNL
3) SKEEIYDKNIGENKEIYDDKNIGENKEIYDKNIGENKEIYDDKNIGENKETYDKNIGENKEIYDDKNIGENKEEIYDINIRESKEEIYEDTNVRKSKGEITDDTNMGESKGRDFGTNAKESKEDIHDDTNIWETKEVTNIDEGVVESKEEMPCGKILMTNQEETTGDMSATKNQEETANDSNVVESQEETACVTNEVESQEEADCDANEVENQETAYNINAESQKEMDSSVRGLESQDERGDGRGITESKKEWEGNINVAGSQEEMAGNARIMESQVPSKSNKTTDDDPDNVSTLQGKRKHDDDVGHEEMKKKLEDNFSN
387
436
544
422
500
863










Molecular Recognition Features






MoRF SequenceStartStop




1) NARIME
2) TLQGKRKHDDDVGHEEMKKKLEDNFS
3) TQFLLYKQ
812
837
504
817
862
511