<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04767

Description Uncharacterized protein
SequenceMILTKQLDLPCYEYPPYVSTSTPRTNLAKELEKYNRPPTEFQTYQSKLYPGKPIAPKPKDSSIDRPNILSKRPNYKPQYRYDPQVPVALNLSTKAAAAAAAAAAASTTASTTNTVNCVTNGSGLDLTMKPMPGASVAGVPASTSVNVTAGLTTTATTTIASITTTTSLPGGNMPLTSRSNTSNGSTNSSSPGNCAIAIAAATAAAAAAAASGGGGGGGGGSGGGGGAAGGVGGGGGAGTGLMETANVNVMQQQQQQQQQQQQQQQQQLQQQQHPHQNHHHQQQQQQQQQQQQHQQQPPPPPPPPPHQHQQQQQSPHHQQQQQHQQQQQPQHTVHQVSQPDTGTLSSHQTHHHQQQQPDDLMVSSSPSALSVVTSIPASLSSPPLNTAISSSSSSSKGDYNGLPVSPVNVPALEKTVCVNGIASPKSPSSLSKASPISSTPPRTSREGRELIHCPTPGCDGSGHVSGNYASHRSLSGCPLADRATVLASHVEQKCPTPGCDGSGHITGNYSSHRSLSGCPRAAKLKKILGKDGERKDDEPLR
Length541
PositionKinase
OrganismOctopus bimaculoides (California two-spotted octopus)
KingdomMetazoa
LineageEukaryota> Metazoa> Spiralia> Lophotrochozoa> Mollusca> Cephalopoda> Coleoidea> Octopodiformes> Octopoda> Incirrata> Octopodidae> Octopus.
Aromaticity0.02
Grand average of hydropathy-0.757
Instability index62.12
Isoelectric point9.08
Molecular weight56274.32
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04767
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.03|      19|      27|     256|     282|       1
---------------------------------------------------------------------------
  251-  267 (37.55/ 8.01)	QQ.......QQQQQQQQQQQQQQQ
  271-  294 (39.82/21.33)	QQhphqnHHHQQQQQQQQQQQQHQ
  316-  332 (34.66/ 7.62)	.......HHQQQQQHQQQQQPQHT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.89|      15|      18|     457|     471|       2
---------------------------------------------------------------------------
  457-  471 (34.30/21.01)	GCD..GSGHVSGNYASH
  476-  489 (17.98/ 7.47)	GCPlaDRATV...LASH
  498-  512 (33.61/20.44)	GCD..GSGHITGNYSSH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.11|      18|      40|     298|     315|       3
---------------------------------------------------------------------------
  298-  315 (40.82/14.63)	PPPPPPPPHQ.HQQQQQSP
  339-  357 (32.29/10.14)	PDTGTLSSHQtHHHQQQQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.85|      14|      17|     209|     222|       4
---------------------------------------------------------------------------
  181-  194 (21.11/ 7.28)	TSNGSTNSSSPGNC
  209-  222 (26.83/11.34)	AASGGGGGGGGGSG
  227-  240 (24.91/ 9.98)	AAGGVGGGGGAGTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.81|      10|     104|      95|     104|       5
---------------------------------------------------------------------------
   95-  104 (17.28/10.77)	AAAAAAAAAA
  199-  208 (17.53/11.02)	AAATAAAAAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.08|      23|      26|       3|      28|       7
---------------------------------------------------------------------------
    5-   27 (43.53/22.45)	KQL...DLPCYEYPPYVSTSTPRTNL
   29-   54 (35.55/14.00)	KELekyNRPPTEFQTYQSKLYPGKPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.19|      23|      41|     105|     135|       8
---------------------------------------------------------------------------
  105-  127 (41.62/16.93)	ASTTASTTNTVNCVTNGSGLDLT
  137-  154 (29.91/22.53)	AGVPAST..SVN.VT..AGLTTT
  156-  176 (34.66/11.95)	TTTIASITTT.TSLPGGN.MPLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.40|      19|      26|     363|     388|       9
---------------------------------------------------------------------------
  363-  385 (28.49/18.97)	SSSPSALSVVTSIPASlsspPLN
  390-  408 (32.90/11.66)	SSSSSSKGDYNGLPVS....PVN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04767 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAAAAASGGGGGGGGGSGGGGGAAGGVGGGGGAGTGLMETANVNVMQQQQQQQQQQQQQQQQQLQQQQHPHQNHHHQQQQQQQQQQQQHQQQPPPPPPPPPHQHQQQQQSPHHQQQQQHQQQQQPQHTVHQVSQPDTGTLSSHQTHHHQQQQPDDLMVSSSPSALSVVTSIPASLSSPPLNTAISSSSSSSKGDYNGLPVSPVN
2) PSSLSKASPISSTPPRTSREGRELIHCPTP
3) QSKLYPGKPIAPKPKDSSIDRPNILSKRPNYKP
4) TIASITTTTSLPGGNMPLTSRSNTSNGSTNSSSPGNCAIAIAAA
205
427
45
158
408
456
77
201










Molecular Recognition Features






MoRF SequenceStartStop




1) AATAAAA
2) EFQTYQSKLYPGKPI
3) IDRPNILSKRPNYKPQYRYD
4) KELEKY
5) LSGCPRAAKLKKILGKDGERKDDEPLR
200
40
63
29
515
206
54
82
34
541