<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04736

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMCNLLTSAMETKVTSKTSSLKALLLRAWRERWSDLQWGINIKTILPRGVSGDVYNLADCILQQALVGLGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCILSLLEFLESIQVGITCRGKPEEDLLAAAVLSIVHWLLQCYLHTLTKMPQNSPLTPQPTELMDKPASILKQMLSSNFLCAMMYLAKYDDKDLYIEVVKKCQEIEALLKTSSLKSSVPIEESLKKLCNLEVDCLALSPEMTQMESITHCLQPLFAVQVLLNPSTETSVFVNQMLMVQRLKNYTNARLYCEIIRACLMCLHNVTNTFKESQWGAFTFLKVPLILKELHVAHSNGDDKPCEYSQDILDSFELLLQFTPLLDIMDTACSCNSVECLLNALQKVNLVTEKQAKQLSSRRDGIAATLQKLEPSTTTPSIPKVIVRAEPTLSGILKTLNADYIKIHEALLSMLYQVLTGKSFELIMAVATVEGKLKTFVTKLIKFNECSKQVNEPVPPKTAATRGMLFDVSFLMLCSIVQTYGSDAVLEEGGGDSFFEQWVRECMPERNQPKSPQKMLQNIDPARVDALLAQINSPDPDFKSSNIKWHIACQSAMGAVKELLCAWESDVLGASDVKRALDGLRATTCCLPVCAAAWLCAYMSITHQDALLKPMNMVQHFLTPLPGDEMQDNLKERSSLMSQIIRKMQYDVHPPTQSKTKVLSMSHSIISRQPILEQLETVWRNINQRGWIDFQATQSLESLLSTGGSLWFVTNIVKEVLKYRYQEELDQAVDLAFAIFHLDIENCTLDLINHIIPQYLYNSLQSEELVEPQSSVLAKLCVYCTFSTLEYNNSNPSRGNNRKRVRRDLDADELDALGVPNKILRLNEAGDSNPIFGSQSPQAQGSTNGQKSVVLRDPLLSALNGLFTIFTFLAGRDGEVSQQTHFILQFLRLMVQCGKDRTRIVLQGMPQTLVPCLLKALPELFTTDILLRFYDIQTAAGRKATARDLCMLRNINLKPTK
Length999
PositionTail
OrganismHabropoda laboriosa
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Apoidea> Apidae> Habropoda.
Aromaticity0.07
Grand average of hydropathy-0.034
Instability index50.78
Isoelectric point6.67
Molecular weight112085.12
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04736
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     244.06|      68|     196|     147|     249|       1
---------------------------------------------------------------------------
   59-  100 (44.18/ 9.68)	CIL.......QQALVGLGPNQLV...LSYLKHSLSSQ.LVSyaaVLQRISKYD........................
  147-  218 (112.35/57.83)	CYLhtltKMPQNSPLTPQPTELMDKPASILKQMLSSN.FLC...AMMYLAKYDDKDLYIEVVKKCQEIEALLKT.SS
  285-  301 ( 1.13/28.80)	................................................LKNYTNARLYCEIIRAC............
  685-  747 (86.40/36.15)	.......KMQYD..VHP.PTQSKTKVLSMSHSIISRQpILE...QLETVWRNINQRGWID.FQATQSLESLLSTgGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.19|      16|      17|     920|     935|       4
---------------------------------------------------------------------------
  920-  935 (29.60/18.88)	QQTHFILQFL.RLMVQC
  938-  954 (24.59/14.48)	DRTRIVLQGMpQTLVPC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.47|      33|     308|     238|     273|       5
---------------------------------------------------------------------------
  238-  273 (55.22/40.12)	DCLalsPEMTQMESITHCLQPL..FAVQVLL......NPSTETS
  543-  583 (49.25/28.59)	ECM...PERNQPKSPQKMLQNIdpARVDALLaqinspDPDFKSS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04736 with Med24 domain of Kingdom Metazoa
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