<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04714

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVAGPTEHGLQADVIFVIEGTAVNGAYLNDLKTNYLIPTLEYFSQGGIEDREYVSENSTTLYGIVVYHAADCLPAPCTETFGPYANPHKLLLVLDKLELVGGKGESFANIGEGLATGLQCFEDLQLRREPNTASQKHCILICNSPPYQIVIQESYKFAGHTIEQLASLYQERNINLSILSPRKIPALFKLFEKAGGDLQSSQTKNYAKDPRHLVLLRNYNLKERPVSPTIGGAVHNTPGTAAQIPLSPLQSNDSPNTNQVQQNITQPSQPQGPPFRNQTPQNITSVHQPVVPMAAAMNAGRPPYNPQISAPPTYHPTSVAARAGHTRWRPFVTPGTTGPANTQSSALIAQLNQPPPSMGLNVSQFGQRMDVANTNVMTANAQQQQQQQQQQQQQQLTQQQQLRLTMQLQQQQQQQQQQNVQQQGSMPITAQPTHGQAGPQLTVSCVSQSVPTQVPQTVTASQTQASASSVSQQQQVTHSQTQGNVPAGSVGPGPQISTPRERQTIWQGIIEWVEKAKTPADAQKQTRHLPCQVSANSKDGDPELKADTWPQKLIMQLMPKQLIGNIGGSYLKNSKSVLFHPTPCEALESLTKVMNSGFVSCVHFTFLQATAACDIKVLILLYTAERRTYLGFIPNDQTGFVDRLRKVIQQQKTSHASMRQGQAGAAQGNAITGPMPTTGTSQGGILMSQTNTIAMGGGQITQNVVSSNPQQQTLTSSAGPQNQINMQSGGITGPQVAPASGTMIGQQRPQFDDIEIARHQNLLKIQQLRQTLEAAQQQEAQYKSQLEVNIQQNLEVAQQQEMQYKQQLEAQQAQRALNPAGMTNQQANAPRLMRPVSNMGLRHLLQQPQPPYRQQVLGLQQQMVGPRGQMTTRPMAPGNPQNQQFEDVSNYDFLG
Length895
PositionUnknown
OrganismHabropoda laboriosa
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Apoidea> Apidae> Habropoda.
Aromaticity0.05
Grand average of hydropathy-0.562
Instability index55.48
Isoelectric point8.82
Molecular weight97875.09
Publications

Function

Annotated function
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP04714
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     281.95|      52|      57|     413|     467|       4
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  276-  320 (50.32/13.65)	..........................................RNQTPQNIT..svHQPVV..PMAAAMNAGRPpyNPQIS..AP......P......TYHPTSVA
  323-  370 (48.08/13.21)	AGHTR.......................................................wrPFVTPGTTGPA..NTQSSalIAQLNQPPPsmglnvSQFGQRMD
  371-  459 (66.09/20.85)	VANTNvmtanaqqqqqqqqqqqqqqltqqqqlrltmqlqqqqQQQQQQNVQ....QQGSM..PITAQPTHGQA..GPQLT..VSCVSQSVP......TQVPQTVT
  460-  514 (71.01/25.39)	ASQTQ..............................asassvsQQQQVTHSQ....TQGNV..PAGSVGP......GPQIS..TPRERQTIW......QGIIEWVE
  798-  842 (46.45/12.01)	..........................................QQQEMQYKQqleaQQ.....AQRALNPAGMT..NQQAN..APRLMRPV.......SNMGLR..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     143.51|      27|      28|     688|     714|       5
---------------------------------------------------------------------------
  651-  681 (36.97/13.48)	QKTShasmR..QGQAGAAQGNAITGPMPTTGTS
  682-  710 (39.88/15.12)	QGGI..lmS..QTNTIAMGGGQITQNVVSSNPQ
  711-  739 (33.15/11.32)	QQTL..tsSagPQNQINMQSGGITGPQVA..PA
  860-  881 (33.52/11.52)	...........QQQMVGPRGQMTTRPMAPGNPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.20|      19|      27|     515|     540|       6
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  515-  536 (31.05/26.72)	KAKT.PadaQKQTRHL.PCQVSAN
  545-  565 (26.15/ 7.29)	KADTwP...QKLIMQLmPKQLIGN
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Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP04714 with Med25 domain of Kingdom Metazoa

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