<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04700

Description C-type lectin (Fragment)
SequenceMALMAVASAQFPNGRILEPPVPSQCVQRNIHERYADNKGYFFSWRDPALRGVEEDWLTARNYCRQRCMDLVSLETSDENEWVKARIVQDKVKYIWTSGRLCDFKGCNRPDLLPNEVNGWFWTAELQKLAPTTNRQQNDWSEGGGIGKPQPDNRELHQGGAAEHCVAILNNFYNDGVHWHDVACHHRKPFVCEENDALLKYVRYTNPNLRRPRLGPPDVYPQEPRQKEDELTSTNVKQGFSTTPHSGDEFGTARNCNYSAAKIGQFFSGILSKKEELNTLPDCGRKRQQVNPKDNFWPATVRTKPQIEAWFKDLAGNKPLSLLAKKAPNFNKKEEIFITLTEFQVSMPRAAWFIKLSSAYTVAVSEAKIKKRQLPDPTTVMMSQWSGEHRAFAIETFFKSNDSYEIARRQLFSHFGIRRISDGPKWTTTLIKFLKDQIPKLSEHYTSGAPGNQPARWLHSKQHMLGTESTDWRQSLKLWHYCCRLAKYMLDEGLLDRHDFLTLFLPLALQHTCEFVCCEGLSRRLATTCAKKAAAICSMLSDATLRTLNQPAAFVKLERNDGTPNPQLPVDVKEEPGSPSRDSKIKLQTVLNAALNPVYEAEQEIAARSKKAEMFANCAAPNKDNLDAKDPEWACSYAVVRVLCEWAENVRMDLDDSKIDDDLDKLLQHIKEDQQNSMDAPDSPKDPGEPSHSATSNITKAAVSRHYHYTMHFPLPPAEAEHTPHDANQQICKLFSKKFSIDVAEGGKIKKHSRSEFNFEAVTQ
Length763
PositionKinase
OrganismOperophtera brumata (winter moth)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Lepidoptera> Glossata> Ditrysia> Geometroidea> Geometridae> Larentiinae> Operophtera.
Aromaticity0.09
Grand average of hydropathy-0.657
Instability index45.97
Isoelectric point7.95
Molecular weight86841.27
Publications
PubMed=26227816

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
carbohydrate binding	GO:0030246	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP04700
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.54|      43|      96|     529|     574|       1
---------------------------------------------------------------------------
  529-  574 (67.84/47.64)	AKKAAAICSMlsdATLRTLNQPAAFVKLERNDGTPNPQLP...VDVKEE
  627-  672 (72.70/43.80)	AKDPEWACSY...AVVRVLCEWAENVRMDLDDSKIDDDLDkllQHIKED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.77|      14|      15|     336|     349|       4
---------------------------------------------------------------------------
  336-  349 (24.82/16.60)	FITL.TEFQVSMPRA
  352-  366 (17.95/10.30)	FIKLsSAYTVAVSEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.10|      11|      39|     236|     246|       5
---------------------------------------------------------------------------
  236-  246 (22.48/16.45)	KQGFS..........TTPHSG
  263-  283 (15.62/ 8.84)	GQFFSgilskkeelnTLPDCG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP04700 with Med12 domain of Kingdom Metazoa

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