<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04667

Description RNA polymerase II holoenzyme cyclin-like subunit
SequenceMATDFWSSSHYKRWIVDRATLRQARREDLKYVDDPDHLYFLAIYFGNAISKLGKKLGLRQRAIATASVFFRRFYLKNAYCETDPFMVIAACCYVAAKAEESPVHIKNVVTESRSLFSQDAYNAKYFPSDHTKLAEMEFYLVDDLECDLVVFHPYRTLLTLCKKETPESASLFGSEEENALQTAWFIINDTYRSDLCLLHPPHIIAIAALYLTFVIHSPPGKVPSPVSADISAFATHSPTPAPQPRRSSRQHPPLSVETKPEDKSQDPISFFAGLNVSLPLVATVVQEIISLYTLWERVSTPIEMDEAEGYSEEEYVTPKFMSRLLLRMREARLGEMAHLACGRPVAINKMLERAQAAG
Length358
PositionKinase
OrganismTermitomyces sp. J132
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Lyophyllaceae> Termitomyces> unclassified Termitomyces.
Aromaticity0.11
Grand average of hydropathy-0.171
Instability index62.95
Isoelectric point6.14
Molecular weight40568.00
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:InterPro
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP04667
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     133.66|      41|      44|     113|     153|       1
---------------------------------------------------------------------------
  113-  153 (72.71/60.30)	RSLFS....QDAYNAKYFPSDHTKLAEMEFYLVDD.LECDLVVFHP
  155-  200 (60.95/49.21)	RTLLTlckkETPESASLFGSEEENALQTAWFIINDtYRSDLCLLHP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.14|      15|      46|      25|      43|       2
---------------------------------------------------------------------------
   25-   43 (23.36/23.44)	RREDLK..YVD.DPdhlyFLAI
   71-   88 (22.78/11.77)	RRFYLKnaYCEtDP....FMVI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP04667 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
NANANA

Molecular Recognition Features

MoRF SequenceStartStop
NANANA