<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04625

Description Putative cell cycle control protein Cwf15
SequenceMTTAHRPTFDPAQGKEALRGPAYHQRLLPAHTHLKTRQLGQGGEGEAQQRDLRAELLQAEAAHFAKKRGIPVDEPTVDNTAPKRQIEDGPSGGDPVGTEDEDPEAKRRRILEETRDIDADSDGSEDDSSEEESDDEEDEAAELMRELEKIKKERQEQKEKEERERAAEEEEKREYDIAKGNPLLNAQDFNLKRRWDDDVVFKNQAGEPKIREEKSLSTCLFPAQLPAIVQSQTPFTANTHGNFKHYYTFMSNGNVIMDRINTNISQLLQRFENIMATATVESTSHTSTAVETYQLDVESTALVRAAEDILSLTRTMKETWLFGKLNTLGEDESDVKRREELERDADAIQKAIEEGGLLKPAK
Length362
PositionHead
OrganismAspergillus nomius NRRL 13137
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.05
Grand average of hydropathy-1.017
Instability index60.27
Isoelectric point4.80
Molecular weight40929.57
Publications









Function






Annotated function

Involved in pre-mRNA splicing.



ECO:0000256	ARBA:ARBA00003777

GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
spliceosomal complex	GO:0005681	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
mRNA splicing, via spliceosome	GO:0000398	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04625
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.12|      35|      37|      65|     101|       1
---------------------------------------------------------------------------
   65-   98 (46.55/24.91)	......AKKRGIPvdEPTVDNTAPKRQIEDGPSGGDPVGT
   99-  136 (54.20/24.53)	EDEdpeAKRRRIL..EETRDIDADSDGSEDDSSEEESDDE
  330-  355 (28.37/10.06)	EDE.sdVKRREEL..E..RDADAIQKAIEEG.........
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04625 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MTTAHRPTFDPAQGKEALRGPAYHQRLLPAHTHLKTRQLGQGGEGEAQQRDLRAELLQAEAAHFAKKRGIPVDEPTVDNTAPKRQIEDGPSGGDPVGTEDEDPEAKRRRILEETRDIDADSDGSEDDSSEEESDDEEDEAAELMRELEKIKKERQEQKEKEERERAAEEEEKREYDIAKGN
1
181










Molecular Recognition Features






MoRF SequenceStartStop




1) LRGPAYH
2) PVGTEDEDPEAKRRRILEETRDI
18
95
24
117