<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04623

Description Uncharacterized protein
SequenceMAPLLGSWTAPSAGGPSKAHLHTSPQKNILYVDAYDSFSYNVVAMLEEVLGVKVTVIMIDSEWPGGNKTEFLQCFEAVVLGPGPGDPNVPEDIGIMRDIWVLSDADLLPVFGICLGFQSLCLHHSIAIERLPYPLHGQVYRISTAEKDVFENLQDVEVTLYHSLYAKLDDSLEAALTEYSGEQIKANADLDLLAWLPIEQDNVSGRTIIPMAVRHSEKPFWGVQFHPESCKSDRAVCSELLKKWWELTLDYNKKHGRGGCGNLPEDIIRRQSDVASLPEIALTMLNWCASTSRSSAFRSLTTSKLNAEFICEHLNAPGSPTVLFQSNGRYSIISVPGPTSWRLEYYAQAETLLVERLQAHSNEYTDCSVKKSLSVHDLWETLRYLMDMKKVESGDDSVPFWGGFLGYFSYEMGLACLARPKTHSDDPHGSLPPQNCAAAPDPADVSLLWSERSVIVDNETGRITIQSTRNADNVSNGWLDETLQYITELSRAGVLENEDVSFDTGYLDTVLRQCVIHFPDEQTYKRQLEACKAELEAGESYELCLTCETSITLPSPSKDSERIAFPWELYKRLRKYNPAAFSAYARLGTVKVVSSSPECFLNWDRSFTLEMKPMKGTVRKSASMTMKKAKEILGSTKEMAENLMIADLIRHDLYGICGSGGVHVEKLLEVEDHGRVYQMITHVKGDVDPGRPGFAVRNVPHLRSSNMSAYGLTALQRCLPPGSMTGAPKERSCMHLSLIEARKRGIYSGVMGFLDLGGGGSFSVLIRTAFSCSDDKDNEQTWRIGAGGAVTILSTADGEWNEMLTKLTTVCGVFAPSDLQGSGKLSTIAIDFMASAQDGSMEEILWRSPAHVQMMGGFLHSNNILFYFAESPFFDATSNNASLAIQANYNETLRHFVETREAFEGRLKTMQGLEFVVAYDPLQAAAQSETSFAHEPSNTWVIRKQTRRKRAGQDDEVVVLSTYFVVGDCIYMAPSVASVVGNRLLSAVTSLTSLLKTASSLPSFTPSHGHTYMPPVPKPTDSSQPGTQSQQSKENTPMPDADSTKALLVGPQTANAGAVLQDTRTFAESFSLLARYGEEFMDENPLVGEPGSFILSKSGDTDRGAVSKQPPNVSAQGASLERLKSRSTRLAKHPRKEPLRRPSMITRCERRRPRLGVERTSPKIHDTLVLITLGTW
Length1176
PositionHead
OrganismAspergillus nomius NRRL 13137
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.08
Grand average of hydropathy-0.270
Instability index47.73
Isoelectric point5.65
Molecular weight129851.76
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
4-amino-4-deoxychorismate synthase activity	GO:0046820	IEA:UniProtKB-EC
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
folic acid biosynthetic process	GO:0046656	IEA:UniProtKB-KW
glutamine metabolic process	GO:0006541	IEA:UniProtKB-UniRule
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro
tetrahydrofolate biosynthetic process	GO:0046654	IEA:UniProtKB-UniPathway









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04623
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.43|      21|     252|     188|     209|       1
---------------------------------------------------------------------------
  188-  209 (33.99/25.90)	ADLDLLaW..LPIEQDNVSGRTII
  443-  465 (32.44/19.69)	ADVSLL.WseRSVIVDNETGRITI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     111.64|      38|     163|     629|     710|       2
---------------------------------------------------------------------------
  105-  149 (55.66/13.14)	ADLL..PVFGIClGfqSLCLHhsiaIER.LPYPLHGQVYRISTAEK.DV
  646-  687 (55.98/92.05)	ADLIrhDLYGIC.G..SGGVH....VEKlLEVEDHGRVYQMITHVKgDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.92|      28|     338|       6|      33|       5
---------------------------------------------------------------------------
    6-   33 (51.29/28.31)	GSWTAPSAGGPSKAHLHTSPQKNILYVD
  328-  355 (49.63/27.17)	GRYSIISVPGPTSWRLEYYAQAETLLVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.64|      18|     172|      81|     104|       7
---------------------------------------------------------------------------
   81-  104 (23.86/32.66)	GPGpGDPNVPEDIgIMRDiwvlSD
  256-  273 (37.78/21.90)	GRG.GCGNLPEDI.IRRQ....SD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.92|      47|     458|     466|     519|       8
---------------------------------------------------------------------------
  466-  519 (69.93/65.97)	QS.TRNADNVSNGWLdetLQYITELSRAGvlENEDVSFDTGYLdtVLRQCVIHFP
  927-  974 (80.98/53.98)	QSeTSFAHEPSNTWV...IRKQTRRKRAG..QDDEVVVLSTYF..VVGDCIYMAP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04623 with Med6 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FTPSHGHTYMPPVPKPTDSSQPGTQSQQSKENTPMPDADSTKALLVGPQTA
2) VGEPGSFILSKSGDTDRGAVSKQPPNVSAQGASLERLKSRSTRLAKHPRKEPLRRPSMITRCERRRPRLGVER
1004
1087
1054
1159










Molecular Recognition Features






MoRF SequenceStartStop




NANANA