<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04609
Description |
Mediator of RNA polymerase II transcription subunit 4 |
Sequence | MGSLLEPNDHQPLTNQFELFLNQFNQITQTVFNQIASSSLLSSSSSSATSSNQLHEISMLQEIIQLKSYLYNLLEITSKHGRNSKKIQNLYLTLSKLNSNHFKKKLDQIFAIKNKLNTICSDGQNEKICFEEHKNLALTPNHIMSYARLIAPYTSAPPAPSTADQDQPINPSTGLDLQDPSLRFLMPFPTEDVIRRGRMGQEMSAPVNGAIEPLNSGNEIGALLGEIRTADGARPTQNQANAHLAAYPTMPPRRLPPPPLPEADDDLFDLDLNPDL |
Length | 276 |
Position | Middle |
Organism | Puccinia striiformis f. sp. tritici PST-78 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina>
Pucciniomycetes> Pucciniales> Pucciniaceae> Puccinia.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.472 |
Instability index | 49.50 |
Isoelectric point | 5.48 |
Molecular weight | 30615.22 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364141
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP04609
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 47.64| 16| 18| 73| 90| 1
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73- 90 (21.20/22.59) LLEITSKHGRnsKKIQNL
94- 109 (26.44/19.44) LSKLNSNHFK..KKLDQI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 109.42| 30| 100| 142| 171| 2
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142- 171 (55.95/24.08) HIMSYARLIAPYTSAPPAPSTADQ..DQPINP
243- 274 (53.47/22.77) HLAAYPTMPPRRLPPPPLPEADDDlfDLDLNP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 40.41| 12| 18| 30| 41| 3
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30- 41 (19.51/13.27) TVFNQIASSSLL
49- 60 (20.90/14.69) TSSNQLHEISML
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