<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04608
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MSSPGSSSSSDSSASSSSNPFDPSTLTQLQQQQHPRTTTTDLEQAINNLDPTTIEANSQATTTFTLSGFTNNNSNPMQSQNTDLTSIINTQTTNGPSQPISKTAHHVITAPSRGWMSQRKGRAVHIEDDPQSSLRNEIEGEFEDLDQSSEQHLYTSSHSSQRIIELGIVEEQLSQLLNLASDVLGSLGPPLDEDESTTTAIKSFSSSINEYFELLNKIQSRLRSSMSYLRVARISTRSLFEPAHVTIPNCPVGLGDLNLTATHSLSSINQTAPVGTTDPTFNFSAPNHHQSAGKGIQESSPTLSLGSLVAERNAWKDLVDSLELIKAQQRSNPV |
Length | 334 |
Position | Head |
Organism | Puccinia striiformis f. sp. tritici PST-78 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina>
Pucciniomycetes> Pucciniales> Pucciniaceae> Puccinia.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.575 |
Instability index | 65.81 |
Isoelectric point | 4.99 |
Molecular weight | 36163.09 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP04608
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 78.01| 19| 21| 70| 88| 1
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36- 54 (27.80/11.79) RTTTTDLEQAI....NNLDPTTI
55- 77 (23.77/ 9.19) EANSQATTTFTlsgfTNNNSNPM
78- 100 (26.45/10.92) QSQNTDLTSIIntqtTNGPSQPI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 39.78| 13| 19| 118| 133| 2
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118- 133 (18.88/22.20) QRKGravHIEDDPQSS
137- 149 (20.89/13.95) EIEG...EFEDLDQSS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 39.08| 14| 16| 206| 221| 3
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206- 221 (15.48/18.82) SSINeYFElLNKIQSR
224- 237 (23.60/15.35) SSMS.YLR.VARISTR
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 58.73| 17| 21| 251| 270| 4
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251- 267 (29.86/15.98) PVGLGD..LNLTATHSLSS
273- 291 (28.87/ 9.03) PVGTTDptFNFSAPNHHQS
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