<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04569

Description Mediator of RNA polymerase II transcription subunit 30
SequenceMSGQYPGGYNNPLAGHRGQFNPQQQQQQQLMNQMQMGSSAGAGGMMPGAGGGPGGGGMMSMGGAGGYGQGGMMTQQGNPMQQQGMQGMAGSVGGGGMGPGVMNPVGMQSPSHVQQQLMQQQQQMQQQMGPMGPQMTMGMAGHVGIVGGSGAGGGGGSPQVSNLMPQQQQMQQNVGMQQGHQMQAGPSSSNMSAMLAQQQQQQSLQQTSQQSPAGQLQQSSLQTQSQQMPQTSGQHQQQQQQQPQPSSNNVLSISQQPHKEINIVTLSRVGQETVQDITSRFQEIFTALKVIQPTSSRDNGTVKKVQEHFRTIRLLFKRMRLIYERCSDGYPQGMEYTHVESLIPYKDETDHRNLEGTQCEEYRKALQENQELIDTVKLKNRQLREIIDRTRIIVWEINTMLSMRRS
Length406
PositionHead
OrganismLucilia cuprina (Green bottle fly) (Australian sheep blowfly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Oestroidea> Calliphoridae> Luciliinae> Lucilia.
Aromaticity0.03
Grand average of hydropathy-0.815
Instability index65.02
Isoelectric point9.10
Molecular weight44252.33
Publications
PubMed=26108605

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04569
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     355.88|      81|      84|      20|     103|       1
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    3-   89 (154.84/34.33)	GQYPGGYN..NPLAGH.rgqFNP...QQQ..QQQQLMNQMQMGSSAGAGGM.MPGAGGGPGGGGmmsMGGAGGYGQ.GGMMTQ.......QGNPMQQQ.GMQGMA
   90-  178 (122.44/23.38)	GSVGGGGM..GPGVMNpvgmQSPshvQQQlmQQQQQM.QQQMGPMGPQMTMgMAGHVGIVGGSG...AGGGGGSPQvSNLMPQ.......Q.QQMQQNvGMQ.Q.
  179-  245 (78.60/12.40)	....GHQMqaGPSSSN.msaMLA...QQQ..QQQSL.QQTSQQS...............P..........AGQLQQ.SSLQTQsqqmpqtSGQHQQQQ.QQQPQP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.97|      20|      26|     265|     284|       2
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  253-  268 (21.06/13.96)	ISQQPHKEI.....NI........vTLSR
  269-  297 (25.06/18.19)	VGQETVQDITSRFQEIftalkviqpTSSR
  298-  314 (17.85/10.56)	.DNGTVKKVQEHFRTI.........RL..
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04569 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSGQYPGGYNNPLAGHRGQFNPQQQQQQQLMNQMQMGSSAGAGGMMPGAGGGPGGGGMMSMGGAGGYGQGGMMTQQGNPMQQQGMQGMAGSVGGGGMGPGVMNPVGMQSPSHVQQQLMQQQQQMQQQMGPMGPQMTMGMAGHVGIVGGSGAGGGGGSPQVSNLMPQQQQMQQNVGMQQGHQMQAGPSSSNMSAMLAQQQQQQSLQQTSQQSPAGQLQQSSLQTQSQQMPQTSGQHQQQQQQQPQPSSNNVLSISQQP
1
257










Molecular Recognition Features






MoRF SequenceStartStop




NANANA