<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04566

Description Protein bric-a-brac 1 (Fragment)
SequenceEKKKHTKQHSLLSLVIMSVQQFCLRWNNHQPNFISVCSSLLHNGTLVDVTLAAEGRQLQAHKIVLSACSSYFQTLFTTNPCQHPIVILKDVQYDDLKTMVDFMYYGEVNVSQEQLPHILKTAEMLKIKGLAEMPTDPANLTKSDSKSSNDATELVGSGGNNGQLGGGNSGGGSNAGGGGNTSSGGLGSSSGGGSVSDSIWGSTESQFQQQQQQQQQQQQQQQQQQQHQQHHQQLQQHHHQQQQQQQQQLHTQLQNSQTQTSQQQQQQQQQQQQHHQQQLRRTPSPLGAGASPATRRKRLRKSSNNGSGERTNSEDHNTSLDAATAGGLTLSQMSQMSFGGAATNSALSGLAAHSLHTAKLLKEASNNDLETNPQDSDSLDDTHGHVHMQIKPEVDMSGVPQSMPLDISGATTPSEHDAPNSQSAHSGLQWTVVEPNYSRFSLSSCPTNLIGNNNNQNQSNNNNNNSSSSDQQQQQQQQQQHQRQQQEAVASQQQQQQQQQQQQQHLQQLQQYQHQQNSAYSPQIITVSGYTNAAAAAVAAAQNLSPPSPNDGNMVQSVYSQGPTPTQSPVGNASGSVGGNNMASINSANNANIKRKRSVNPQGDENFIRALEAVRSGGIGFCKAARLYGVNNRTLWLEYKKRGYPVSRPSIKSRVVKQEPNLSPSPTPPANATDDTNENYDHMAAAVAAAQTAALNMQIPPTSETPTPSLMCTPHHAGTAAGATTHPTMGVMSFLDTRHLDFPASLHSMSRQRYIDASAGGGGAGAGTINNSMSTSSAHSATVVATETVPTTIIPMHLHQHHHQSQHPHSHTSSHSHEPQQQEQQHQSHHQNIQQHSHPTLIQPSPNQSSQANTSSSSSIVTTSSAAAAASALLQQTTLSCDTQTPNAATNHHHSLVAAPQPQATTIYVQNYATATPIIVHPTDNTTTTYMAKLTALPPTKPTCALKVFHMEITIRQQAYNSFNGNSYYDQNKTVNKFISFFSKTEDTKASLGLSLAQSPQQQHQQQLEPHQPPQPAQMGTKRNRVLTRQPRVKRDSDSLSNNQISPEPTTGSLDFEPFGASQTLYSSAVHGLHHMPTHHHPHHHGHGHGHHHLLTVPPRIERHSSEPAPSLSPNSPHLLSVPQTTPFLVKQHSDPLLPSQHSAHLASGSGGSGNLTNPFAPLHRQYSHPLTGAAGTYLASSAPLQHSHHISLPESIYETASPPPAGSSQYIVPQTNTQPPQASSSSSNNNNATSTSSASPTKSISLPQFTTTYMGNERSNSSNVACSPPIPRVPTVQLAERSASEDNASSATAQTSASSSSTSSSTVNTNKFRNSKSASAVMLTERAGGTSSSGGQSGSFEHLPTLRVRNEELQRSVSSPQTNREIITLENPRSSHCPVIRPGPALGCNFCWNTIDGHGRILRRKTKYHCPECQTNLCIVPCFQEYHERLNNEIEAATASSSSTNNTTNTSRANNSSSSSSANASSNNNNTSNNNSQQQETRTNVQQTSSNATSTTSRHYTKTETF
Length1507
PositionKinase
OrganismLucilia cuprina (Green bottle fly) (Australian sheep blowfly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Oestroidea> Calliphoridae> Luciliinae> Lucilia.
Aromaticity0.04
Grand average of hydropathy-0.838
Instability index64.52
Isoelectric point7.99
Molecular weight162669.42
Publications
PubMed=26108605

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-UniRule

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04566
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     221.31|      20|      20|     216|     235|       1
---------------------------------------------------------------------------
  204-  223 (38.43/11.66)	ESQFQQQQQ....QQQQQQQ....QQQQ
  224-  243 (48.12/16.58)	QQQHQQHHQ....QLQQHHH....QQQQ
  244-  267 (33.75/ 9.28)	QQQQQLHTQlqnsQTQTSQQ....QQQQ
  479-  498 (33.04/ 8.92)	QQHQRQQQE....AVASQQQ....QQQQ
  823-  846 (33.94/ 9.38)	EQQHQSHHQ....NIQQHSHptliQPSP
 1001- 1016 (34.02/ 9.42)	QQQHQQ.......QLEPH.Q....PPQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.97|      13|      19|    1071|    1083|       2
---------------------------------------------------------------------------
 1071- 1083 (31.78/13.63)	HGLHHMPTHHHPH
 1133- 1145 (22.20/ 7.14)	HSDPLLPSQHSAH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     108.61|      19|      19|    1166|    1184|       3
---------------------------------------------------------------------------
  918-  939 (24.05/ 8.03)	IIVHPTDNTTTTYmakLTALPP
 1166- 1184 (31.34/12.96)	QYSHPLTGAAGTY...LASSAP
 1186- 1204 (31.49/13.07)	QHSHHISLPESIY...ETASPP
 1210- 1226 (21.73/ 6.46)	QYIVPQTNTQPPQ...ASSS..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.70|      19|      23|    1430|    1452|       4
---------------------------------------------------------------------------
  436-  454 (30.51/12.18)	NYSRFS..LSSCPTNLIGNNN
 1450- 1470 (29.19/12.40)	NTSRANnsSSSSSANASSNNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.58|      17|      23|     156|     173|       5
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  156-  173 (33.66/18.38)	GSGGN..NGQLGGGnSGGGS
  176-  194 (31.93/13.15)	GGGGNtsSGGLGSS.SGGGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      99.96|      22|      23|    1247|    1268|       6
---------------------------------------------------------------------------
 1238- 1257 (27.60/13.86)	..SAS..............PTKSIS..LPQFTTTYMGN
 1258- 1280 (23.30/10.15)	ERSNS..............SNVACSppIPRVPTVQLA.
 1297- 1315 (24.09/10.83)	..SAS...............SSSTS..SSTVNTNKFRN
 1316- 1351 (24.97/11.60)	SKSASavmlteraggtsssGGQSGS..FEHLPTLRVRN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     283.64|      81|     146|     535|     620|       7
---------------------------------------------------------------------------
  272-  341 (58.12/23.13)	.....QQHHQQQLRRTPSPLgagA..SP..AtrrkrlrkssNNGSGertnSEDHNT..SLDAATAGGL....TLSQMSQMSF.........GGA...............................
  547-  620 (96.86/56.53)	PsPNdGNMVQSVYSQGPTPT...Q..SP..V..........GNASG....SVGGNNMASINSANNANIKRKRSVNPQGDENFIRAleAVRSGGIG..............................
  663-  699 (22.81/ 6.74)	.................SPS...P..TP..P..........ANATD....DTNEN..................................................ydhmAAAVAAAQtaalNMqI
  700-  790 (105.85/50.70)	P.PT.........SETPTPS...LmcTPhhA..........GTAAG....ATTHPTMGVMSFLDTRHLDFPASLHSMSRQRYIDA..SAGGGGAGagtinnsmstssahSATVVATE....TV.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.57|      21|      30|    1377|    1402|       9
---------------------------------------------------------------------------
 1377- 1402 (32.52/35.56)	HCPVIRPGpaLgCNF.CWNtiDGHGRI
 1410- 1431 (40.05/23.21)	HCPECQTN..L.CIVpCFQ..EYHERL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.99|      11|      30|     875|     886|      10
---------------------------------------------------------------------------
  875-  886 (16.28/10.24)	QQTTLSCDTQtP
  892-  902 (18.71/ 7.14)	HHHSLVAAPQ.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.15|      22|     287|     797|     819|      11
---------------------------------------------------------------------------
  797-  819 (42.44/23.31)	HLHQHHHQSQHPhSHTSSHSHEP
 1087- 1108 (44.70/20.38)	HGHGHHHLLTVP.PRIERHSSEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.88|      12|      29|     368|     380|      12
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  368-  380 (17.39/13.10)	DLETNPQdSDSLD
  395-  406 (22.49/12.18)	DMSGVPQ.SMPLD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04566 with Med12 domain of Kingdom Metazoa
Unable to open file!