<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04555

Description Mediator of RNA polymerase II transcription subunit 25 (Fragment)
SequenceDKLNCVELHCTQKMEMESLADVVFLVEGSAANGAYINELKTNYIVPTLEHFSQGPIEDREYLISERYSTQYCVVLYRTTANLLEPMCTTFGPYSSPQKVMDLFERLPLTGGGMESCANLAEGLATAHICFDDMKEHRARYNKDGNLSTQKHCILMCNSSPYSMPVMECWKYTGKTVEQLAGLFHERKINLSIIAPRKIPILFKIFMKADGDQPLTAKKYAKNIRHLVLLKGYHLKERPQSPNSAAAAMGNQANQVVGGPNQQQQQQQQQQQKSAQQQNSGLPMDNTHASPQQQQLQQQQVSQMGGMNPNQQPGNALNQQLLQQQQQQQQQQQQQFGGQNPMQNPNFQGQGNRWVFNPNQQQQQARPQFLPNAPGGPMVSMGGPVNQGGMPVQNSALISQLSAPPNQNVNPMMQQQQQIRMQMLNQQQQQQMQQLQQQQQQQQQQQNVMNSNMSGPGGPNPQQQQVPVVANNQPNTSMANQQNPGPSSDQAVMRDKIWSGTLEWVEKSKPDQQKIPRTLQCTVTANIKDGEPEIKAINWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFKPQPCEALDALAKNMTTIFAGCVHFTTPPNMPACDIKVLILLYTAEKNAFLGFIPNNQSMFVERLRKVIQQKQSMGMQQTAGGGPNSMQQQQQQQQQQGQQQLQNPMAGQISGNMNPQQQQQQQDPNQQQQQHFNQYNPQQQMNMQMAGGPMNQQMMGGPPMSGGPDQMVGNNPMQQQQMTMMQHQRMPMMAGGNPNNPQQQQMPPQQMQQRMVRPMMNNNPGLRHLLQQQSTPGQQFRPQMGGVGGGPGGVPMGGGGMPNPNQMTGGPGGPGGGPNRPFDDNFEYM
Length855
PositionUnknown
OrganismLucilia cuprina (Green bottle fly) (Australian sheep blowfly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Oestroidea> Calliphoridae> Luciliinae> Lucilia.
Aromaticity0.05
Grand average of hydropathy-0.853
Instability index57.29
Isoelectric point8.94
Molecular weight95334.16
Publications
PubMed=26108605

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04555
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             9|     646.05|      62|      62|     706|     767|       1
---------------------------------------------------------------------------
  269-  315 (62.38/10.58)	............QQQKS...........AQQ.QNSGL.P.........M........D.N.THA....SPQQQQ....LQQQQVSQMGGMNP.....NqqpgNA
  316-  376 (75.28/14.45)	L..........NQQLLQQQQ...QQQQQQQQ.QFGGQnP.........MQ.N....PNfQGQGNrwvfNPNQQQQQA..RPQFLPNAPGG.P............
  379-  431 (58.54/ 9.43)	..................SM....GGPVN.Q...GGM.PvqnsalisqLSAP....PN.QNV......NPMMQQQ....QQIRMQMLNQQQQ.....Q....QM
  435-  476 (73.22/13.83)	Q..........QQQQQQQQQ...QN.VMNSN..MSGP.............GG....P...........NPQQQQ.........VPVVANNQP.....N....TS
  479-  539 (65.16/11.41)	N..........QQN..........PGPSSDQaVMRDK.I.........WSGT....LE.WVEKS....KPDQQKIPRTLQCTVTANIKDGEPeikaiN....WP
  610-  656 (62.28/10.55)	L..........YTAEKNAFL...GFIPNNQS.MF......................VE.RL..R....KVIQQKQSMGMQQ.....TAGGGP.....N....SM
  661-  697 (64.53/11.23)	Q..........QQQQ.........QG...QQ.QLQNP...........MAG........QISGN...mNPQQQQQQQD.............P.....N....QQ
  706-  764 (123.86/29.02)	N..........PQQQMNMQM...AGGPMNQQ.MMGGP.P.........MSGG....PD.QMVGN....NPMQQQQMTMMQHQRMPMMAGGNP............
  791-  847 (60.79/10.10)	GlrhllqqqstPGQQFRPQMggvGGGP.......GGV.P.........MGGGgmpnPN.QMTG....................GPGGPGGGP.....N....RP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.33|      21|      27|     551|     574|       4
---------------------------------------------------------------------------
  549-  572 (32.67/29.24)	KH....LVGNIGGQFlkdSKMVVFKPQP
  573-  597 (34.67/22.05)	CEaldaLAKNMTTIF...AGCVHFTTPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.33|      22|      96|      16|      40|       6
---------------------------------------------------------------------------
   16-   40 (32.03/36.35)	MESLADvvfLVEGSAANGAYINELK
  113-  134 (41.30/34.99)	MESCAN...LAEGLATAHICFDDMK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.23|      17|      25|     200|     216|      10
---------------------------------------------------------------------------
  200-  216 (29.49/15.21)	ILFKIF.MKADGDQPLTA
  227-  244 (24.74/11.62)	VLLKGYhLKERPQSPNSA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04555 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KGYHLKERPQSPNSAAAAMGNQANQVVGGPNQQQQQQQQQQQKSAQQQNSGLPMDNTHASPQQQQLQQQQVSQMGGMNPNQQPGNALNQQLLQQQQQQQQQQQQQFGGQNPMQNPNFQGQGNRWVFNPNQQQQQARPQFLPNAPGGPMVSMGGPVNQGGMPVQNSALISQLSAPPNQNVNPMMQQQQQIRMQMLNQQQQQQMQQLQQQQQQQQQQQNVMNSNMSGPGGPNPQQQQVPVVANNQPNTSMANQQNPGPSSDQAVMRDKIWSGTLEWVEKSKPD
2) KQSMGMQQTAGGGPNSMQQQQQQQQQQGQQQLQNPMAGQISGNMNPQQQQQQQDPNQQQQQHFNQYNPQQQMNMQMAGGPMNQQMMGGPPMSGGPDQMVGNNPMQQQQMTMMQHQRMPMMAGGNPNNPQQQQMPPQQMQQRMVRPMMNNNPGLRHLLQQQSTPGQQFRPQMGGVGGGPGGVPMGGGGMPNPNQMTGGPGGPGGGPNRPFDDNFEYM
230
640
510
855










Molecular Recognition Features






MoRF SequenceStartStop




NANANA