<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04521

Description Uncharacterized protein
SequenceMQRYHAASCTSAVNNNNSLGGISNRDANARSDSSSLSANFSLNSRRASSLAPYRLKCEKEPLNSRLGPPDFHPQTVSCPEETLTKEYVQSGYRETVEGLEEAKEISVTQVNTFTKPVVLKCKEAIRKRLRAINESRAQKRKAGQVYGEPLSGSLLSKPGLFPEQKSCGEEFKKRWIEGLSQYHKSLRSLADHVPHGYRKKSLFDVLIKNNVPLLRATWFIKVTYLNQIRPGSSSVSSGSPDRIQLSRTEIWTKDVTDFLQCLLDELFSRNNSHSIPQNRERTQHMLYSGSVQQKSDPASLALDSEEPSLHFKWWYGVRILHWHHAEGLILSSQVIDWVFLQFQDKDLLKVMQFLLPIIYGLLETITSCQTYVRKLVDVTLRFLKEPSVGGSDIADNSRRAYTCSALAEMLQYLILSVPDTFVGLDCFPLPQCLMTFTENDGSLHSQLPVYCEQLKKDSEGVSQVTSNKNLDIKYPSSWFRRVVSSIQKRATCLTKAASPGYSGQNVAKAVQALDKALLQGDVQEAYTFLFEGLSDSSVHEGWIAEVSPCLRSSLKWIRSVGPPLIYSVFLLCEWCTCDFRDIRTSLLHDVKFTGRKDFSQLYVAARLMKQKVRKIQRSEKEKTGYDNQISWKKVEKGCIEMSDFFESPSPLHDIIVCWMDQHEAQKGEGSKRVQLLLTELTRCGIFSPLAYARQLLVSGIMDKDGPVVNPDRRKRHYRILKQLSVSCMHDVFDEAQSADRSFLVEAIHIYANERRLLLRGLLGDEHKQIRSSNNASKKQKNLPVSQRDHSLPPSVYQLKMIQSLSYVSHSKSKKNGPDLEKLKLSILELLLLPKCVADAGVDDSQVNLKRPVGLISSKLDIAEGTPGCEECRRAKRQKLGEEKFPYLQGPLSSNPLDDDDNWWVRKEPKSLDSLKVEQPIKPSKQGSRGRQKSVRKTQSLAQLAASRIEGSQGASTSHVCDNKVGCPHHRPVPEGDAPKSADGNRVTNATDIVSIGKMLKRLKFAEKRSISAWLVSSVKQVIEETERMSPKSGQLNRTISSVDEKSSARWKLGEDELSIILYLMDMCTEVPMAIRFLIWLLPKALGNLNTPIHGGRNMMMQPRNVESHACEVKEPFLLSAIRRYENIIVAVDLLPEILSSTMHRAATVLASNGRLSGSPTFLYARYLLKKYGNVSSVIEWEKIFKTTCDKRLLSELESVKSQNGECGFSFSVPSGVEDLDDLIRQKVSCNRLSRTGMNMREIVQRYVDDAVHHLFGKERKLFGSGAQKNAGIEKWGDGYQIAQQIVVGLMDCIRQTGGAAQEGDPSLVASAVSAIVGNVGPAIAKMPDFTAVPCHLNSPSPTGSLSFARRVLRIHINCLCLLKEALGERHSRAFEIALATEASSALAVVLLPGKGARGQFQLSPDAHESSMNMSNDVPNNPSKIAVGRATKIAAAVSALIIGAIIHGVSSLERMVTVFRLREGLDLIQFVRNSRSHSNGNARSAGALKIENALEVYIHWFRLLIGNCRTVSDGVIVELLGEASVMALSRMQRTLPLNLVLPPAYALFAFMIWKPFIFSITPGSREEIPQLLQSLTLAIGDAIKHAPFRDICLRNTNGFFNIVTSDSTDAEFASILELNGSDRHLKAKAFIPLRARLFLNALVDCKLPHSLQDDSSRLSGTNDPKVQYGESETKISDRLVSALDTLQPAKFHWQWVELRLFLSELTLIGKFDSSDTQSVAEAIRSLTPNSDKGGSLENENNFIPIVLTRLLVRPDAAPLLSEVVHLFGRSLEDSMLLHVKWFLEGHDVLFGRKSIRQRLVNFADSKGFSTKVQFWKPWGWCNSSSDSIGNRGDKRRLETPSVEEGEVVEEDYKRLARGVSKLSDREDPNQQFVTERALIELVLPCIDRSSDDSRSRFASELIKQMNNIEQQVSGVASGTSKQTGSSLSGSEGFTNKASTRKSLKGSSPGLSRRAAAVAIDSTPSSPAALRASVSLRLQLLVRLLPTICTDG
Length1990
PositionKinase
OrganismSpinacia oleracea (Spinach)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> Caryophyllales> Chenopodiaceae> Chenopodioideae> Anserineae> Spinacia.
Aromaticity0.07
Grand average of hydropathy-0.300
Instability index48.62
Isoelectric point9.07
Molecular weight221612.08
Publications
PubMed=24352233

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04521
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     193.38|      58|     170|     876|     941|       1
---------------------------------------------------------------------------
  876-  941 (89.46/79.81)	RQKLGEEKFP...YLQGPLSSNPLDDDDNWWVrkEPKSLDSLKVeqPIkpskQGSRGRQKSVRKTQSLA
 1049- 1109 (103.92/68.66)	RWKLGEDELSiilYLMDMCTEVPMAIRFLIWL..LPKALGNLNT..PI....HGGRNMMMQPRNVESHA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.09|      38|     261|    1132|    1178|       4
---------------------------------------------------------------------------
  570-  610 (61.25/34.81)	LLCEWCTCDFRDIRTSLLHDVKFTGRKDFsqLYvAARLMKQ
 1133- 1170 (63.84/51.39)	LLPEILSSTMHRAATVLASNGRLSGSPTF..LY.ARYLLKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     193.14|      58|     428|     238|     296|       5
---------------------------------------------------------------------------
  238-  296 (97.47/69.82)	GSpDRIQLSRTEIWTKDVTDFL....QCLLDELFSRNNSHSIPQNRERTQHMLYSGSVQQKSD
  669-  730 (95.67/63.23)	GS.KRVQLLLTELTRCGIFSPLayarQLLVSGIMDKDGPVVNPDRRKRHYRILKQLSVSCMHD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     298.81|      78|     428|      21|     101|       9
---------------------------------------------------------------------------
   21-  101 (125.06/105.58)	GISNRDANARSDSSSLSANFslNSRRA...SSLAPY.RLKCEKEPlNSRLGPPDFH.PQTVSCPEETLTKE..YVQSGYRETVEGLEE
  396-  456 (60.34/39.55)	......................NSRRAytcSALAEMlQYLILSVP.DTFVGLDCFPlPQ...C.LMTFTENdgSLHSQLPVYCEQLKK
  460-  531 (113.41/84.36)	GVSQVTSNKNLDIKYPSSWF....RRV...VSSIQK.RATCL.....TKAASPGYS.GQNVAKAVQALDKA..LLQGDVQEAYTFLFE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.01|      49|     428|     973|    1028|      14
---------------------------------------------------------------------------
  973- 1028 (67.94/67.44)	PegDAPKSA..DGNRVTNATDIVSIGKMlkrLKFAEkrSISAWLVSSVKQVIEETERM
 1404- 1454 (75.06/51.46)	P..DAHESSmnMSNDVPNNPSKIAVGRA...TKIAA..AVSALIIGAIIHGVSSLERM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04521 with Med12 domain of Kingdom Viridiplantae
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