<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04445

Description Pre-mRNA-processing protein 40A
SequenceMANNPQAPGGSQFIPVAPSSQSQQFIPANSQPFRPVGNGMSMPVSNMGMPSGQLPPHYHQMSQQYPPRPGQQALQGPSSTQGGIPMPYIPPNVATSYGSLQHSSTSQTINNHTYQNAPAVSGSSEIWGLSSGAQSIPPIAPSVHSVQPPSSVSASTMPSNLFQQSSDWQEHTASDGKRYYYNKKTSQSSWEKPFDLMTPLEKADASTVWKEFTTPEGRKYYYNKLTKQSKWTIPDELRLAREQAEKEAVHTGEIVVPSVPSNLVNIPPSEKTATTGSITGGIVPISANSASFTALPVVSSTSIPTSSTLGGLPNLNSPATADSTFEHASPPVFINALKDASATITEDNTLDPKRLPDVVSHLENKSHEVKGSVLVTGKASEILLEEKSNSDGLYVYASKQEAKNAFKELLESANVESDWSWEQAMKLIVNDKRYDALRTIGERKQAFNEYLRQRKKTEVEERRIKYKKAREDFIKMLEECEQLTPLMQWRKVESLFEDDERLKAIERLRDREDLFDTYLKDLQKKEKLKAFEDHKRITTEYRSFLESCDFIKVNTRWRKVHNLRDDDERCSSLDKIEQLEIFQGYIHDLEKEEEEQKKIEMQQLRRQERKNRDEFRRLMEDHISAGTLTAKTHWGDYCMKVRGLSPYLDVASNTSGSTPKDLFDDTTKELETQYHDDKTQIKDALKMGKITLASRSTFEDFKSSISMDNSLEKISEINMKLVFEELLERLREKLQKLGDNFADLLYSIKDINASSYWDECKLLFEECQEYISLNDESYAREVFEEYIAHLQEKAKLKAKREKGREEKEKEKERREREKEADRSQKDDVEIENFDFNNIKEEKKREREKDRKHRKRHHIILTNDGSPERGDEPKKSKRDSDHKRSRNFLHGYTTDSDSEHRHRKHKKYHDGSHTSGMHEELEDGELGEDSKTR
Length932
PositionUnknown
OrganismZostera marina (Eelgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Zosteraceae> Zostera.
Aromaticity0.07
Grand average of hydropathy-0.986
Instability index60.34
Isoelectric point6.08
Molecular weight106858.90
Publications
PubMed=26814964

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04445
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.98|      37|      38|     168|     204|       1
---------------------------------------------------------------------------
  168-  204 (72.79/42.53)	WQEHTASDGKRYYYNKKTSQSSWEKPFDLMTPLEKAD
  209-  245 (71.19/41.45)	WKEFTTPEGRKYYYNKLTKQSKWTIPDELRLAREQAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     153.01|      29|      29|     840|     868|       2
---------------------------------------------------------------------------
  785-  807 (29.50/14.55)	EYIAHLQEKAKLKAKRE..K.......GREEK
  810-  839 (33.28/17.41)	EKERREREKEADRSQKD..DVEIENfDFNNIK
  840-  868 (52.29/31.80)	EEKKREREKDRKHRKRH..HIILTN.DGSPER
  871-  900 (37.95/20.95)	EPKKSKRDSDHK.RSRNflHGYTTD.SDSEHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     395.79|      66|      66|     461|     526|       3
---------------------------------------------------------------------------
  400-  458 (72.82/49.78)	................QEAKNAF.KELLE...SANVESDWSW....EQA....MKL..IVN.......DKRYDALRTIGERKQAFNEYLRQRKKTE
  461-  526 (106.23/76.56)	ER.RI..KY.......KKAREDFIKMLEE...CEQLTPLMQW....RKV....ESL..FED.......DERLKAIERLRDREDLFDTYLKDLQKKE
  534-  593 (85.32/59.79)	HK.RIttEY.......RS.......FLES...CDFIKVNTRW....RKV....HNL..RDD.......DERCSSLDKIEQLE.IFQGYIHDLEKEE
  596-  674 (67.09/45.18)	QK.KI..EMqqlrrqeRKNRDEFRRLMEDhisAGTLTAKTHWgdycMKV....RGLspYLD..........VASNTSGSTPKDLFDDTTKELETQY
  676-  725 (31.61/16.75)	DD.KT..QI.......K....DALKM....................GKItlasRST..FEDfkssismDNSLEKISEI.NMKLVFEE.........
  728-  766 (32.72/17.64)	ERlRE..KL.......QKLGDNFADLLYS...IKDINASSYW....DEC....KLL..FEE...................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     109.64|      25|      25|     320|     344|       4
---------------------------------------------------------------------------
  290-  316 (32.20/21.01)	ASFTALPVVSSTSIPTssTLGGLPNLN
  317-  341 (39.19/27.34)	SPATADSTFEHASPPV..FINALKDAS
  342-  366 (38.25/26.48)	ATITEDNTLDPKRLPD..VVSHLENKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      85.81|      21|      25|      88|     109|       5
---------------------------------------------------------------------------
   88-  108 (39.35/19.14)	Y.IPPNVATSYGSLQ..HSSTSQT
  114-  134 (23.99/ 8.10)	YqNAPAVSGSSEIWG..LSSGAQ.
  136-  156 (22.47/ 9.61)	..IPP.IAPSVHSVQppSSVSAST
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.26|      15|      25|     246|     261|       6
---------------------------------------------------------------------------
  246-  261 (23.88/22.06)	KEAvHTGEI...VVP.SVPS
  271-  289 (17.38/ 9.76)	KTA.TTGSItggIVPiSANS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.50|      18|      57|      10|      27|       7
---------------------------------------------------------------------------
   10-   27 (35.45/19.11)	GSQFIPVA....PSSQ........SQQFIP
   38-   67 (22.83/ 9.93)	NGMSMPVSnmgmPSGQlpphyhqmSQQYPP
   70-   85 (29.22/14.58)	GQQALQ.G....PSS.........TQGGIP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04445 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KAKREKGREEKEKEKERREREKEADRSQKDDVEIENFDFNNIKEEKKREREKDRKHRKRHHIILTNDGSPERGDEPKKSKRDSDHKRSRNFLHGYTTDSDSEHRHRKHKKYHDGSHTSGMHEELEDGELGEDSKTR
2) MANNPQAPGGSQFIPVAPSSQSQQFIPANSQPFRPVGNGMSMPVSNMGMPSGQLPPHYHQMSQQYPPRPGQQALQGPSSTQGGIPMPYIPPNVATSYGSLQHSSTSQTINNHTYQNA
3) PPIAPSVHSVQPPSSVSASTMPSNLFQQSSDWQ
797
1
137
932
117
169










Molecular Recognition Features






MoRF SequenceStartStop




1) EHRHRKHKKYHDGSHTSGMHEELEDGEL
2) HHIIL
3) IPMPYI
898
856
84
925
860
89