<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04444

Description U-box domain-containing protein 35
SequenceMEHEVDDPTIVAVAVNESNNSEYAVKWALKKFIPIGINLIKLIYVQPETIPNDRADANNKDMEWKSGSTVLLPYIQMCLNRKVEAEPHIIEGNDIPAAISEEITNCAINKLVIGCSSHSALSRKFKGSESSKIAEMVPSFCTVYTISKGETPLVRSSTSYSKESIRNDTSIYPSISSCESSVHPEITDRESSSPKNSDYPDSLKNRHIRELTSFNPDFTDTTSKTEISQTTIFHSGNLISNFEESSRYSSSSETEYLTVDFDDVSSYGNFGNSILDNEADDLDLLGVKLGHLRGICEKTQNEIFEASQKMNELRALCMEDNRKIEQLYIQEEKIRDIVKKEHKSCDMAKKKFEQMRDFIESEKLTGKNALDRVKYEVEEKQSIEKALKNCQLQDYKKLEWEEIISSTSGLSESLLIGIGENGKVYKGRLHQTTVAIKILQLNEIRQTKKFLQELEVLGRIHHPHLMLLVAACPEHGCLVYEYMENGNLSDRLNCKNNAMPLEWFHRYRIAWEIASALVFLHNSKPKPIVHRDLKPANIFLDRNLVAKIGDFGLSTLLPADLSSSTVFKNTAPVGTLFYVDPEYHRTGMVSPKSDIYSFGMVILQLLTAKLPKRLTFLVEKAIGDGCLEDVLDSRAGKWPSVETEELARMALGCLELTSIDRPDLQTKIVPLLEKLKKVADTALNAALPVHDLIIPNHFNCPILKKVMEEPYVASDGYTYDLKAIKEWFSMNDKSPVTNLDLPNKQLIPNLSLRHAIEDWLSFVCK
Length765
PositionTail
OrganismZostera marina (Eelgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Zosteraceae> Zostera.
Aromaticity0.07
Grand average of hydropathy-0.354
Instability index41.25
Isoelectric point5.63
Molecular weight86444.74
Publications
PubMed=26814964

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04444
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.77|      38|      40|     143|     180|       1
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  143-  180 (64.28/42.75)	VY.TISKGETPLVRSS...TSYSKESIRNDTSIYPSISSCES
  182-  223 (55.49/35.90)	VHpEITDRESSSPKNSdypDSLKNRHIRELTSFNPDFTDTTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.76|      35|      46|     675|     709|       2
---------------------------------------------------------------------------
  675-  709 (60.41/50.09)	LKKVAD.TALNAALPVHDLIIPNHFNCP..ILKKVMEE
  721-  758 (50.35/40.27)	LKAIKEwFSMNDKSPVTNLDLPNKQLIPnlSLRHAIED
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     117.83|      40|      46|     518|     561|       3
---------------------------------------------------------------------------
  518-  561 (56.40/49.23)	VFlHNSKPKPIVHRdLKPAniFLDRNLV...AKIGDFGLS..TLLPADL
  566-  610 (61.43/37.89)	VF.KNTAPVGTLFY.VDPE..YHRTGMVspkSDIYSFGMVilQLLTAKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.31|      13|      20|     360|     379|       4
---------------------------------------------------------------------------
  360-  379 (16.20/27.12)	EsekltgkNAL......DRVKYEVEE
  384-  402 (18.11/10.35)	E.......KALkncqlqDYKKLEWEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.29|      30|      40|     285|     314|       6
---------------------------------------------------------------------------
  285-  314 (49.84/32.74)	LGVKLGHLRGICEKTQNEIFEASQKMNELR
  327-  356 (50.45/33.22)	LYIQEEKIRDIVKKEHKSCDMAKKKFEQMR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.69|      37|      39|      17|      53|       7
---------------------------------------------------------------------------
   17-   53 (63.76/45.84)	ESNNSEYAVKWALKKFIP.IGINLIKLIYVQPETI.PND
   56-   94 (56.93/40.13)	DANNKDMEWKSGSTVLLPyIQMCLNRKVEAEPHIIeGND
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04444 with Med32 domain of Kingdom Viridiplantae
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