<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04436

Description Heat shock cognate 70 kDa protein
SequenceMEGKAEGPAIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPINTVFDAKRLIGRRVGDVSVQSDMKLWPFKITPGPAQKPLITVQYKGEQKSFSAEEISSMVLTKMREIAEAYIGVSVKNAVVTVPAYFNDSQRQATKDSGVIAGLNVLRIINEPTAAAIAYGLDKKKSTSGEKDVLIFDLGGGTFDVSILSIDEGIFEVKATAGDTHLGGEDFDSRLVNHFVQEFRRKNKKDISGNARPLRRLRTACERAKRTLSSTAQTTIEIDSLYQGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKNSIDDVVLVGGSTRIPKVQQLLQELLNGKELCKSINPDEAVAYGASVQGAILSGEGTKKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKDQIFSTYSDNQPGVLIQVFEGERSRTRDNNLLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGKKNKITITNDKGRLSKDDIEKMIHEAEKYKTEDEVHKKKIEAKNALENYAYSMRNTIKDDKIASKLDASDKKKIEDAIDSAISWLDNNQLAEVDEFEDKMKDLESLCNPIIAKMYQGEGGGDMPGAGMSEGASSGKGPKIEEVD
Length646
PositionUnknown
OrganismZostera marina (Eelgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Zosteraceae> Zostera.
Aromaticity0.06
Grand average of hydropathy-0.414
Instability index36.19
Isoelectric point5.35
Molecular weight70816.57
Publications
PubMed=26814964

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04436
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.05|      23|      26|      33|      55|       1
---------------------------------------------------------------------------
   13-   31 (27.34/16.54)	..DLG..TTYSCVGVWQNDRVEI
   33-   55 (40.66/28.00)	ANDQGNRTTPSYVAFTDTERLIG
   57-   78 (34.06/22.32)	AAKNQVAMNPINTVF.DAKRLIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.79|      45|      74|     412|     459|       2
---------------------------------------------------------------------------
  412-  459 (67.86/56.72)	AGGVMTVLIPRNTTipTKKDQIFSTySD....NQPGVLIQVFEGERSRTRDN
  488-  536 (68.93/45.29)	ANGILNVSAEDKTT..GKKNKITIT.NDkgrlSKDDIEKMIHEAEKYKTEDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.95|      13|      39|     351|     365|       3
---------------------------------------------------------------------------
  351-  365 (17.41/18.58)	KVQQLLqeLLNGKEL
  393-  405 (22.54/15.49)	KVQDLL..LLDVTPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.43|      21|     241|     366|     390|       7
---------------------------------------------------------------------------
  366-  390 (30.15/30.31)	CksiNPDEAVAY....GASVQGAILSgEG
  609-  633 (38.27/23.47)	C...NPIIAKMYqgegGGDMPGAGMS.EG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04436 with Med37 domain of Kingdom Viridiplantae
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