<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04421

Description Pre-mRNA-processing protein 40A (Fragment)
SequenceYFYNKITKQSKWTIPEEVKLAREKMDKISQTIPETVVTSPIKTSVTSNELPSPLAMPSTTAAMVILEGSISDLVTGNDSCIHPDGASGSPSVSTVTLTAVPSNSAIGGTSSLCPTIKHLGPFESTSSTPLSVHVDTTITNFSDIQDRSPAEDVNKSVDSSCKDANKAVPITSPTKSTPLLSKVIDEDQSSYANKQEAKDAFKSLLQSTNIQSDWTWEQAMRLIINDKRYGALKTLGERKQAFNQYLSQKKKKETEERRNKQKKSREEFLNMLEESKELKSSTRWSKAILMFEGDERFNNVEHHRDREDLFEAYIIDLEKMERAKILEEYKRNVAEYKVFLRSCDFIKPNSQWRKIQDHLEKDESCFRLDKFDRLKYFQEYLKDLEKEEEEQRKIQKEQVKREERKNRDDFRKLMQEHVSDGIITAKTHWRDYCMKIKDLPIYVAVASNASGATPKDLFEDVIEELQKQYKEDRMELKDAMKMGKFFLTSKSTFEDLKIIISMDDNLQCISKINLKLVYDELLERVKEKEAKQAKKRQRLAENFSNLLSTIKEISSLSKWEECKPFFEDSEEYKSISEECFGREVFDGYVLHLFENAKEIERKRDDDKLKKEREKEERDRRKDKERKEKEKEWDREKGRERHRKDDIAHEGDCIVDANVTREERKRERERKYRRHHHKTIDDSSSDRDEREGGSNKKSRRHSSGRTRSRSTKQHGFTTESDTDSKPKKQKKEANSHRSIYYGDLEDGEVGEDGEIRVI
Length757
PositionUnknown
OrganismZostera marina (Eelgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Zosteraceae> Zostera.
Aromaticity0.07
Grand average of hydropathy-1.087
Instability index52.36
Isoelectric point7.34
Molecular weight88413.22
Publications
PubMed=26814964

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04421
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.15|      24|      24|     617|     640|       2
---------------------------------------------------------------------------
  617-  640 (39.66/18.37)	RDRRKDKE..RKE...KEKEWDREKGRER
  650-  675 (35.62/15.76)	GDCIVDANvtREE...RKRERERKYRRHH
  680-  706 (32.88/13.99)	DDSSSDRD..EREggsNKKSRRHSSGRTR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     421.15|      63|      65|     194|     256|       3
---------------------------------------------------------------------------
  194-  256 (94.58/54.25)	KQEAK..DAFKSLL.Q...S.TN.IQSDWT.W..........EQAMRLIIN.DKRYGALKT..LGE.RKQAFNQYLSQKKKKETEE
  261-  324 (80.92/45.38)	QKKSR..EEFLNMLeE...S.KE.LKSSTR.W..........SKAILMFEG.DERFNNVEH..HRD.REDLFEAYIIDLEKMERAK
  336-  391 (50.95/25.91)	.........YKVFL.R...S.CDfIKPNSQ.WrkiqdhlekdESCFRL....DK.FDRLKY..........FQEYLKDLEKEEEEQ
  401-  472 (62.63/33.50)	REERKnrDDFRKLM.QehvS.DG.IITAKThW..........RDYCMKIKD.LPIYVAVASnaSGAtPKDLFEDVIEELQKQYKED
  473-  532 (70.19/38.41)	RMELK..DAMK..M.G...K.FF.LTSKST.F..........ED.LKIIISmDDNLQCISK..I.N.LKLVYDELLERVKEKEAKQ
  536-  588 (61.88/33.01)	RQRLA..ENFSNLL.S...TiKE.ISSLSK.W..........EECKPFFED.SEEYKSISE..ECF.GREVFDGY...........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.13|      44|      47|      92|     135|       4
---------------------------------------------------------------------------
   45-   89 (26.73/12.51)	...VTSNELPSPLAMPSTTAamviLEGSISDLvtgndsciHPDGA.SGS.........
   92-  135 (74.04/46.87)	VSTVTLTAVPSNSAIGGTSS....LCPTIKHL........GPFES.TSSTP.LSVHVD
  141-  185 (58.36/35.48)	FSDIQ.DRSPAEDVNKSVDS....SCKDANKA........VPITSpTKSTPlLSKVID
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.90|      14|      16|       4|      18|       5
---------------------------------------------------------------------------
    4-   18 (20.44/19.89)	NKITKQSKwTIPEEV
   23-   36 (25.46/16.89)	EKMDKISQ.TIPETV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04421 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FSDIQDRSPAEDVNKSVDSSCKDANKAVPITSPTKSTPL
2) RDDDKLKKEREKEERDRRKDKERKEKEKEWDREKGRERHRKDDIAHEGDCIVDANVTREERKRERERKYRRHHHKTIDDSSSDRDEREGGSNKKSRRHSSGRTRSRSTKQHGFTTESDTDSKPKKQKKEANSHRSIYYGDLEDGEVGEDGEIRVI
141
603
179
757










Molecular Recognition Features






MoRF SequenceStartStop




1) KEANSHRSIYYGDLEDGEVGEDGEIRVI
730
757