<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04416

Description ATP-dependent DNA helicase Q-like 4A
SequenceMSKEAISRRENQIKGSVFDNGVPRVNWTHHIKARENFSCQEKFLSEHFLYSLSKQKPNGGDTSYIRPIACNVQHNQKLQTSDIDNAWNTLHSLQKVKNDYVRPGFTEPSQNHETSIPKQIFDSSKNKGKSLDHYNSTIDVLNKPGNLICDNLGTYHYFSYPEAECLKKNDPSSSCITNSLEKNTETSLMGANDLKVSLPINSTSVAKNSQISNNVETKTTVQNFLDDLDDDEIMKNIDVDQIILEYYRASGTTESSKGRGSLFTCPVPGHYNTDFNDDIVPTELSQKCTHGVKLEECSEVGSRKPFAGYLIVLSNQLIDNVYVFGSQHREDILKRRILLNNKILNIMDNLRNKCRVENTITPQFLAEESSTIIQSETLECTSSVNQTTTQNWNASISFSKSEPEITSPQLKHLNIEYTDGSIDKKWKDAEFPWNQKLEFYNKEVFGNHSFRRNQREVINATMSGCDVFVLMPTGGGKSLTYQIPALISTGVTLVISPLVSLIEDQIMHLLQANIPATFLSASIEWCEQQEILRDLNSKTCKYKLLSDVLIRQLEMMNTHRSLARIVIDEAHCVSQWGHDFRPDYQGLGILKQKFPSIPVLALTATATASVREDIVQALGLKDCIVFRQSFNRPNLWYTVIPKTNKCLDDIDKFINENHFDECGIIYCLSRMDCEKVAEKLQACGHKVSFYHGSMDHRQRTFVQKQWSKNEINIICATVAFGMGINKPNVRFVIHHSLPKSIEGYHQECGRAGRDGQQSSCLLYYTYSDYIRVKNMLSRPNEQDSCSFVYMQVTPSRTGKVLEANLENVLRMVDYCENNADCRRHLQLVHLGEKFDPKNCLGTCDNCSKSWTWIEKDVTNLAKQLVDLVKTTGQRHSSSYILELYKGSLSHVVKKYGHDGLILHGVGKHLAKGVASRVLHHLVVQDFVVESVKRSDTYGSISSILKVNQSRVDSLLSGKETIMLRFPISDKDDFENGRYESAPAKAPYVPNFRSNSDKNKTLDIKTNVLQTKKCNTASSSSHSVSNSNYKSKKRKKASTDIRKNAKIDDYFTESSVHSTKRSKRQGEIVKKTESRPRRQRTDFTGCYLNAIKAFCQWTYGPPSSLPHWVFYLQ
Length1112
PositionUnknown
OrganismZostera marina (Eelgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Zosteraceae> Zostera.
Aromaticity0.08
Grand average of hydropathy-0.538
Instability index49.10
Isoelectric point8.61
Molecular weight126300.54
Publications
PubMed=26814964

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04416
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.00|      20|      23|     864|     886|       1
---------------------------------------------------------------------------
  864-  886 (26.35/24.31)	LVDLVKTTGqrHsSSYIL.....ELYKG
  888-  912 (30.65/16.54)	LSHVVKKYG..H.DGLILhgvgkHLAKG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.70|      12|      23|     753|     764|       2
---------------------------------------------------------------------------
  753-  764 (23.55/12.94)	RDGQQSSCLLYY
  778-  789 (24.15/13.45)	RPNEQDSCSFVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     165.47|      52|     608|      17|      99|       3
---------------------------------------------------------------------------
   41-   99 (82.02/85.02)	EKFLSE.HF.....LYSLSKQkpnggDTSYI..RPIACNvqHNQKLQTSDIDNAWNTLHSLQKVKND
  651-  710 (83.45/34.49)	DKFINEnHFdecgiIYCLSRM.....DCEKVaeKLQACG..HKVSFYHGSMDHRQRTFVQKQWSKNE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      75.58|      18|      24|    1025|    1042|       4
---------------------------------------------------------------------------
  990- 1005 (19.10/ 7.94)	..NFRSNSDKNKTLDIKT
 1025- 1042 (29.25/15.94)	NSNYKSKKRKKASTDIRK
 1052- 1069 (27.22/14.34)	ESSVHSTKRSKRQGEIVK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.37|      23|      23|     486|     508|       5
---------------------------------------------------------------------------
  483-  505 (35.81/24.79)	IPALISTGV.TLVISPLVSLIEDQ
  506-  529 (35.56/24.56)	IMHLLQANIpATFLSASIEWCEQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.80|      19|     414|     409|     436|       6
---------------------------------------------------------------------------
  415-  436 (30.89/34.68)	IEYTDGSIdkkWKDAEFPWNQK
  437-  455 (33.91/14.80)	LEFYNKEV...FGNHSFRRNQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.00|      16|      23|     815|     835|      14
---------------------------------------------------------------------------
  815-  833 (24.62/23.08)	CENNAD.CRRHLQLVhlgEK
  839-  855 (29.38/11.37)	CLGTCDnCSKSWTWI...EK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04416 with Med34 domain of Kingdom Viridiplantae
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