<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04405

Description 70 kDa heat shock protein
SequenceMAVKGEGPAIGIDLGTTYSCVGVWQHDRVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPNNTVFDAKRLIGRKFNDSTVQADLKLWPFKLTSGPAKKPMITVQYKGEQKTFSAEEISSMVLIKMREVAEAYLGSSIKNAVVTVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKKTTSVGEKNVLIFDLGGGTFDVSLLTIEEGIFEVKSTAGDTHLGGEDFDNRMLNHFVQEFKRKNKKDIAGNARSLRRLRTACERAKRTLSSTAQTTIEIDSLYEGIDFYSTITRARFEELNMDLFRKCMEPVEKCLRDAKMDKSSIHDVVLVGGSTRIPKVQQLLQDFFNGKELCKNINPDEAVAYGAAVQAAILSGEGNKKVQDLLLLDVTPLSLGLETAGGVMTALIPRNTTIPTKKEQIFSTYADNQPGVLIQVYEGERARTRDNNHLGKFELSGIPPAPRGVPQITVCFDIDANGILNVSAEDKTTGQKNKITITNDKGRLSKEDIEKMVEEADRYKSEDEEHKKKVESKNALENYAYNMRNTIRDDKIASKLDVADKKKIMDSIDETIQWLDKNQLGEADEFDDKMKELESLCNPIIAKMYQGGAGGGSAMDQAGAGAGPKIEEVD
Length642
PositionUnknown
OrganismZostera marina (Eelgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Zosteraceae> Zostera.
Aromaticity0.06
Grand average of hydropathy-0.438
Instability index33.37
Isoelectric point5.50
Molecular weight70652.31
Publications
PubMed=26814964

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04405
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.59|      19|      74|     448|     466|       1
---------------------------------------------------------------------------
  448-  466 (33.81/22.84)	VYEGERARTRDNNHLGKFE
  525-  543 (31.77/21.03)	VEEADRYKSEDEEHKKKVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.65|      36|     189|     121|     218|       2
---------------------------------------------------------------------------
   81-  119 (59.99/17.08)	FNDSTVQA..D....LKLWPFKLTSGPAkkpMITVQYKGEQKTFS
  154-  195 (50.66/139.64)	FNDSQRQAtkDagviAGLNVLRIINEPT...AAAIAYGLDKKTTS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.42|      18|      21|      38|      55|       3
---------------------------------------------------------------------------
   16-   33 (19.09/10.88)	....TTYSCVGVWQHDRveIIA
   38-   55 (32.56/23.82)	NR..TTPSYVAFTDSER..LIG
   60-   78 (24.77/16.33)	NQvaMNPNNTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.26|      13|      75|     342|     359|       4
---------------------------------------------------------------------------
  342-  356 (17.61/22.81)	LVGGSTRipKVQQLL
  386-  398 (22.65/ 8.77)	LSGEGNK..KVQDLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.06|      11|      25|     206|     216|       9
---------------------------------------------------------------------------
  206-  216 (20.32/10.50)	LGGGTFDVSLL
  234-  244 (21.74/11.68)	LGGEDFDNRML
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04405 with Med37 domain of Kingdom Viridiplantae
Unable to open file!