<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04391
Description |
Mediator of RNA polymerase II transcription subunit 21 |
Sequence | MADILTQLQTCLDQVPHPSTSIPQFKTTNLTLNSQLATQFYATIGYLSTYHDNSPAIPPADVPDAAPALAKIPKNSTAPPVPAGAPVPAQFQASPPAQNPAHGAAGAGTSVGEGGQTPGPAADPNLPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQEKCIRELESELRRVEEERELKMRELKRLRRTLENVLRAVETGIYGDRALLERYS |
Length | 224 |
Position | Middle |
Organism | Aspergillus udagawae |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.471 |
Instability index | 59.10 |
Isoelectric point | 5.19 |
Molecular weight | 24270.03 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 ARBA:ARBA00003669
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP04391
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 56.78| 21| 21| 53| 73| 1
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64- 86 (29.31/11.04) DAAPALAKIP........kNSTAPPvPAGAP
103- 132 (27.47/ 9.96) GAAGAGTSVGeggqtpgpaADPNLP.APDSP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 45.43| 14| 15| 169| 183| 2
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169- 183 (20.90/21.64) EQEKCIRELEsELRR
187- 200 (24.53/19.12) ERELKMRELK.RLRR
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