Description | Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MTSPAPAQAAHPTDQQRLANKIRFETELEFVSCLANPFYLQSLAQQGLFDSEPFLNYLTYLLYFRQPTYSRFLQYPQSLHHLTLLTSSSSFRKAMKEQPLLAQEWAGKMGEGGKKEDGAGAGEAAAAGGAAERNGGDETKQAAAAS |
Length | 146 |
Position | Middle |
Organism | Rhodosporidium toruloides (Yeast) (Rhodotorula gracilis) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Microbotryomycetes> Sporidiobolales> Sporidiobolaceae> Rhodotorula. |
Aromaticity | 0.10 |
Grand average of hydropathy | -0.477 |
Instability index | 59.48 |
Isoelectric point | 5.90 |
Molecular weight | 15905.59 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro |
Binary Interactions |
Repeats | >MDP04367 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 46.18| 14| 15| 114| 127| 1 --------------------------------------------------------------------------- 114- 127 (22.66/11.57) KKEDGAGAGEAAAA 132- 145 (23.52/12.23) ERNGGDETKQAAAA --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) KAMKEQPLLAQEWAGKMGEGGKKEDGAGAGEAAAAGGAAERNGGDETKQAAAAS 2) TYLLYF | 93 59 | 146 64 |
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