<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP04359

Description Mediator of RNA polymerase II transcription subunit 6
SequenceMMQAGGPSRSVMMGQTQGSYMGVPNVVSQSGSSYQQIVSLLHQSFKNPNWPPNFITPDNVLDYFCDPGNVFYDVSSCNQHIRMQNLNRPLHECLQSMQGIQYTVVGTFPPLYVIMKQRRNSPTNVTPLAYYYIVNGTVYQCPDIYTYIQSKLISIVDPLRQALEQARNFNRFNIAKGYYWEFKDSDGETVKKATEEEEKPQLARSTFYQRTRTDQILRELFAKFPPPDDVQFNFGGNEISVENDTSGVVEKSVQSSSVNNQNLTATEDPTSGISQQTAFTSPSSVPLIPAHRSTAESSSGPLSFPGTIPVLGVSSTDSQHETDTKRFKTN
Length330
PositionHead
OrganismBrugia malayi (Filarial nematode worm)
KingdomMetazoa
Lineage
Aromaticity0.10
Grand average of hydropathy-0.536
Instability index54.05
Isoelectric point5.77
Molecular weight36922.76
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP04359
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.32|      45|      46|      87|     132|       1
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   87-  132 (79.27/58.74)	NRPLHECLQSMQGIQYTVVGTFPPLYVIMKQRRN.SPTNVTPlAYYY
  135-  180 (77.06/52.46)	NGTVYQCPDIYTYIQSKLISIVDPLRQALEQARNfNRFNIAK.GYYW
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP04359 with Med6 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NDTSGVVEKSVQSSSVNNQNLTATEDPTSGISQQTAFTSPSSVPLIPAHRSTAESSSGPLSFPGTIPVLGVSSTDSQHETDTKRFKTN
243
330










Molecular Recognition Features






MoRF SequenceStartStop




1) LRELF
217
221